Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 1518756..1519263 Replicon chromosome
Accession NZ_AP017369
Organism Corynebacterium suranareeae strain N24

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag N24_RS07175 Protein ID WP_096455613.1
Coordinates 1519009..1519263 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N24_RS07170 Protein ID WP_096455611.1
Coordinates 1518756..1519004 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N24_RS07130 1514229..1514747 - 519 WP_167382170.1 WHG domain-containing protein -
N24_RS07135 1514783..1515304 - 522 WP_167382053.1 SRPBCC domain-containing protein -
N24_RS07165 1517002..1518105 + 1104 WP_096455609.1 NERD domain-containing protein -
N24_RS07170 1518756..1519004 + 249 WP_096455611.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
N24_RS07175 1519009..1519263 + 255 WP_096455613.1 Txe/YoeB family addiction module toxin Toxin
N24_RS07180 1519369..1519740 + 372 WP_096455615.1 carboxymuconolactone decarboxylase family protein -
N24_RS07185 1519789..1520094 - 306 WP_096459903.1 hypothetical protein -
N24_RS07190 1520465..1520647 - 183 WP_096455617.1 hypothetical protein -
N24_RS07195 1520789..1521127 + 339 WP_096459907.1 META domain-containing protein -
N24_RS07200 1521127..1521687 + 561 WP_096455619.1 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase -
N24_RS07205 1521670..1522377 - 708 WP_077311966.1 IclR family transcriptional regulator -
N24_RS07210 1522631..1524076 + 1446 WP_096455621.1 3-isopropylmalate dehydratase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1508274..1521687 13413


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-67)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10137.67 Da        Isoelectric Point: 9.7996

>T31093 WP_096455613.1 NZ_AP017369:1519009-1519263 [Corynebacterium suranareeae]
MRLVWDRAGWEDYIFWQTTDRKVLKRINTLIEACLRDPFGGIGKPEQLRYGARGAWSRRITEEHRLVYIVKNDDLVILQA
RYHY

Download         Length: 255 bp

>T31093 NZ_AP017369:1519009-1519263 [Corynebacterium suranareeae]
ATGCGACTCGTATGGGATCGTGCTGGATGGGAAGACTATATTTTCTGGCAGACTACGGATCGCAAGGTGCTCAAGCGTAT
AAATACGCTCATTGAGGCATGTCTGCGTGATCCTTTTGGAGGGATAGGAAAGCCTGAGCAATTAAGGTATGGGGCACGAG
GGGCGTGGTCACGTCGGATCACTGAGGAACACCGTCTGGTTTATATTGTTAAAAACGATGATTTAGTAATCCTTCAAGCC
CGTTACCACTACTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9302.42 Da        Isoelectric Point: 4.4929

>AT31093 WP_096455611.1 NZ_AP017369:1518756-1519004 [Corynebacterium suranareeae]
MSISASEARKTLFPLIEKVNNDREAIEIVSRKGNAVLMPADDYAAWQETAYLFRSPANARRLLDAYERATEGVFEVHELD
TE

Download         Length: 249 bp

>AT31093 NZ_AP017369:1518756-1519004 [Corynebacterium suranareeae]
ATGTCCATTAGTGCAAGTGAGGCACGTAAGACCTTGTTTCCGCTGATAGAGAAAGTAAATAACGACCGTGAAGCAATTGA
GATAGTTTCCCGAAAAGGAAATGCTGTATTAATGCCTGCCGATGATTACGCTGCATGGCAGGAAACAGCTTATCTATTCC
GTTCGCCGGCGAATGCACGCCGGCTGTTAGATGCATATGAGCGCGCTACCGAAGGAGTCTTTGAAGTCCACGAGCTTGAT
ACGGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References