Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-PHD
Location 5960962..5961605 Replicon chromosome
Accession NZ_AP017295
Organism Nostoc sp. NIES-3756

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NOS3756_RS24765 Protein ID WP_067774083.1
Coordinates 5961204..5961605 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NOS3756_RS24760 Protein ID WP_067774080.1
Coordinates 5960962..5961207 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NOS3756_RS24730 5957128..5958621 + 1494 WP_067774062.1 insulinase family protein -
NOS3756_RS31285 5958724..5958864 - 141 WP_171843546.1 hypothetical protein -
NOS3756_RS24735 5958858..5959175 + 318 WP_067774065.1 hypothetical protein -
NOS3756_RS24740 5959172..5959540 + 369 WP_067774068.1 aspartyl protease -
NOS3756_RS24745 5959632..5959874 - 243 WP_067774071.1 hypothetical protein -
NOS3756_RS24750 5959855..5960133 - 279 WP_067774074.1 BrnT family toxin -
NOS3756_RS24755 5960141..5960719 - 579 WP_067774077.1 hypothetical protein -
NOS3756_RS24760 5960962..5961207 + 246 WP_067774080.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NOS3756_RS24765 5961204..5961605 + 402 WP_067774083.1 type II toxin-antitoxin system VapC family toxin Toxin
NOS3756_RS24770 5961805..5962659 + 855 WP_067774086.1 mechanosensitive ion channel family protein -
NOS3756_RS24775 5962934..5963788 + 855 WP_067774089.1 mechanosensitive ion channel family protein -
NOS3756_RS24780 5963827..5964024 + 198 WP_067774092.1 hypothetical protein -
NOS3756_RS24785 5964067..5964705 - 639 WP_067774095.1 histidine phosphatase family protein -
NOS3756_RS24790 5965252..5965488 + 237 WP_067774098.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-122)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-41)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 15166.43 Da        Isoelectric Point: 4.8783

>T31049 WP_067774083.1 NZ_AP017295:5961204-5961605 [Nostoc sp. NIES-3756]
VKLLLDTQCWLWWFAQPERLSEEAITHIADETNELWFSVASIWEIGIKVAIAKLPLPEPPDSYISSRMRQLGMRSLEITA
THALRAASLPLHHRDPFDRMLIAQAQLEDITLVSADAIFRQYNDVAIVWAANS

Download         Length: 402 bp

>T31049 NZ_AP017295:5961204-5961605 [Nostoc sp. NIES-3756]
GTGAAGTTGTTGTTGGATACTCAATGTTGGTTGTGGTGGTTTGCTCAACCAGAGAGGTTGAGTGAGGAGGCAATTACACA
CATTGCTGATGAAACCAACGAATTGTGGTTTTCGGTTGCTAGTATCTGGGAAATCGGTATTAAAGTTGCGATCGCAAAGC
TACCATTGCCAGAACCACCAGATAGCTACATTTCTAGCCGTATGAGGCAGTTGGGTATGCGATCATTAGAAATTACAGCA
ACTCACGCTTTACGAGCAGCTTCATTGCCCTTGCATCACCGAGATCCGTTTGACAGAATGTTGATTGCACAGGCACAGCT
AGAAGACATAACGCTCGTCAGTGCTGATGCAATATTCAGGCAGTACAACGATGTGGCAATTGTTTGGGCAGCTAACTCGT
GA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8938.09 Da        Isoelectric Point: 4.5659

>AT31049 WP_067774080.1 NZ_AP017295:5960962-5961207 [Nostoc sp. NIES-3756]
METVNIHQAKTNLSRLLSRVELGEEIIISNRGIPIAKLVPFHNPSNRRASLGLDQGRFTVPDDFDAPLPEDILAAFEGGE
E

Download         Length: 246 bp

>AT31049 NZ_AP017295:5960962-5961207 [Nostoc sp. NIES-3756]
ATGGAAACCGTAAATATCCATCAAGCTAAAACAAACCTCTCACGCTTGCTATCTCGTGTGGAACTTGGAGAAGAAATTAT
TATTTCAAACCGAGGTATCCCAATTGCAAAGTTGGTTCCGTTTCATAACCCATCTAATCGGCGAGCTAGTTTAGGGTTAG
ATCAGGGGCGTTTCACAGTACCAGACGACTTTGATGCTCCTTTGCCAGAAGATATCTTGGCAGCATTTGAGGGTGGTGAA
GAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References