Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1295812..1296325 Replicon chromosome
Accession NZ_AP017295
Organism Nostoc sp. NIES-3756

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag NOS3756_RS05330 Protein ID WP_067765540.1
Coordinates 1296059..1296325 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NOS3756_RS05325 Protein ID WP_067765537.1
Coordinates 1295812..1296066 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NOS3756_RS29405 1291171..1291584 - 414 WP_082727158.1 GFA family protein -
NOS3756_RS05305 1291783..1293039 - 1257 WP_148649981.1 hypothetical protein -
NOS3756_RS05310 1293103..1293780 - 678 WP_067765531.1 hypothetical protein -
NOS3756_RS05320 1295135..1295662 + 528 WP_067765535.1 GNAT family N-acetyltransferase -
NOS3756_RS05325 1295812..1296066 + 255 WP_067765537.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NOS3756_RS05330 1296059..1296325 + 267 WP_067765540.1 Txe/YoeB family addiction module toxin Toxin
NOS3756_RS05335 1296609..1297856 - 1248 WP_067765542.1 pentapeptide repeat-containing protein -
NOS3756_RS05340 1297995..1298942 - 948 WP_067765545.1 F0F1 ATP synthase subunit gamma -
NOS3756_RS05345 1299084..1300604 - 1521 WP_067765548.1 F0F1 ATP synthase subunit alpha -
NOS3756_RS05350 1300727..1301281 - 555 WP_067765551.1 F0F1 ATP synthase subunit delta -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10593.05 Da        Isoelectric Point: 5.8603

>T31045 WP_067765540.1 NZ_AP017295:1296059-1296325 [Nostoc sp. NIES-3756]
MSRKLVWTDEAWSDYLYWQEQDKKTLKRINKLIEATMRLPFEGIGKPEALKENLAGFWSRRIDDTNRLVYAVDDEYLTII
ACRYHYSD

Download         Length: 267 bp

>T31045 NZ_AP017295:1296059-1296325 [Nostoc sp. NIES-3756]
ATGAGTAGAAAGTTAGTATGGACAGATGAGGCTTGGAGCGATTATTTATATTGGCAAGAGCAAGACAAGAAAACTTTAAA
ACGCATTAACAAGCTGATTGAGGCAACAATGCGACTACCGTTTGAAGGGATAGGTAAGCCAGAAGCTTTGAAAGAAAACC
TAGCTGGCTTTTGGTCGCGGCGCATTGATGATACTAATCGGTTAGTTTATGCAGTGGATGATGAGTATTTAACGATTATT
GCTTGTCGGTATCACTATTCTGATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9516.87 Da        Isoelectric Point: 4.8047

>AT31045 WP_067765537.1 NZ_AP017295:1295812-1296066 [Nostoc sp. NIES-3756]
MKVVSFSEARNNLKAVLDQVVEDADYTIITRRDAEDAVVMSLELFNSLLETVHLLKSPANAAHLERSITQFKQGKVMERN
LLDE

Download         Length: 255 bp

>AT31045 NZ_AP017295:1295812-1296066 [Nostoc sp. NIES-3756]
ATGAAAGTCGTCTCTTTTAGCGAAGCGAGAAATAACCTCAAGGCTGTTTTAGACCAAGTGGTGGAAGATGCAGACTATAC
CATCATTACTAGACGGGATGCGGAGGATGCTGTGGTTATGTCGCTAGAGTTATTTAATAGTTTGCTGGAGACTGTTCATT
TACTCAAGTCACCTGCTAATGCTGCTCATTTGGAGCGTTCTATTACTCAGTTTAAGCAGGGGAAAGTAATGGAGCGCAAT
TTGTTAGATGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References