Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 3224681..3225336 Replicon chromosome
Accession NZ_AP014946
Organism Variibacter gotjawalensis strain GJW-30

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GJW30_RS15690 Protein ID WP_096356949.1
Coordinates 3224681..3225100 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GJW30_RS15695 Protein ID WP_096356951.1
Coordinates 3225097..3225336 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GJW30_RS15660 3219839..3220726 - 888 Protein_3104 DMT family transporter -
GJW30_RS15670 3221023..3221409 - 387 WP_096356943.1 hypothetical protein -
GJW30_RS15675 3221406..3222641 - 1236 WP_096356945.1 hypothetical protein -
GJW30_RS15680 3222638..3223669 - 1032 WP_096356947.1 AAA family ATPase -
GJW30_RS15685 3223747..3224649 - 903 WP_096358862.1 DMT family transporter -
GJW30_RS15690 3224681..3225100 - 420 WP_096356949.1 type II toxin-antitoxin system VapC family toxin Toxin
GJW30_RS15695 3225097..3225336 - 240 WP_096356951.1 plasmid stability protein Antitoxin
GJW30_RS15700 3225450..3227879 - 2430 WP_096356953.1 endopeptidase La -
GJW30_RS15705 3228279..3228968 - 690 WP_096356955.1 hypothetical protein -
GJW30_RS15710 3229043..3229726 + 684 WP_130364517.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14715.13 Da        Isoelectric Point: 8.4447

>T31035 WP_096356949.1 NZ_AP014946:c3225100-3224681 [Variibacter gotjawalensis]
MILIDTNVISEPLRKAPAAPVVAWLDAQAIETLYLSAISLAELRYGVAALPAGKRKSALNRDLEARIVALFGQRILPFDT
DAVDAYAAIRARAKSSGLAIGTTDGYIAATAMAHGLIVATRDVKPFKAAGLSVIDPWDL

Download         Length: 420 bp

>T31035 NZ_AP014946:c3225100-3224681 [Variibacter gotjawalensis]
ATGATCCTGATCGATACGAACGTGATTTCGGAACCGTTGCGAAAAGCGCCAGCCGCGCCGGTCGTGGCTTGGCTCGATGC
CCAAGCGATTGAGACGCTTTATCTTAGTGCTATCAGTTTGGCAGAGCTACGATATGGGGTTGCAGCGCTTCCGGCCGGCA
AGCGGAAGTCTGCGCTCAACCGCGATCTAGAAGCCCGTATTGTTGCATTGTTCGGGCAACGCATTCTTCCATTCGATACC
GATGCTGTCGATGCCTATGCTGCAATCCGGGCGCGCGCCAAGTCGTCCGGCCTCGCAATTGGCACAACCGACGGATATAT
CGCTGCAACTGCGATGGCACATGGCCTCATCGTTGCGACCCGAGATGTGAAGCCGTTTAAGGCCGCAGGTCTCAGCGTGA
TTGATCCTTGGGACTTGTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8453.67 Da        Isoelectric Point: 11.1842

>AT31035 WP_096356951.1 NZ_AP014946:c3225336-3225097 [Variibacter gotjawalensis]
MAAVTIRNLSTATHRALKQRAAESGRSTEAEIRSILDAAVRPKGRIKLGSELASIGRKAGGVDLDITRDKTPARTIDLE

Download         Length: 240 bp

>AT31035 NZ_AP014946:c3225336-3225097 [Variibacter gotjawalensis]
ATGGCTGCTGTGACGATCAGAAATCTTTCCACCGCCACGCACCGCGCATTGAAGCAACGGGCTGCAGAGAGCGGACGTAG
TACCGAGGCGGAAATTCGTTCGATCCTCGATGCGGCTGTGCGCCCGAAAGGACGGATCAAGTTAGGCTCTGAGCTTGCCT
CTATCGGCCGCAAAGCGGGTGGCGTAGATCTCGACATTACGCGCGACAAAACACCAGCTCGCACTATCGATCTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References