Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-VagC |
Location | 1340249..1340910 | Replicon | chromosome |
Accession | NZ_AP014946 | ||
Organism | Variibacter gotjawalensis strain GJW-30 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | GJW30_RS06475 | Protein ID | WP_096353179.1 |
Coordinates | 1340503..1340910 (+) | Length | 136 a.a. |
Antitoxin (Protein)
Gene name | VapB1 | Uniprot ID | - |
Locus tag | GJW30_RS06470 | Protein ID | WP_096358694.1 |
Coordinates | 1340249..1340506 (+) | Length | 86 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GJW30_RS06450 | 1336117..1336761 | - | 645 | WP_130364777.1 | hypothetical protein | - |
GJW30_RS06455 | 1336859..1337446 | - | 588 | WP_096353172.1 | GNAT family N-acetyltransferase | - |
GJW30_RS06460 | 1337459..1338730 | - | 1272 | WP_096353174.1 | insulinase family protein | - |
GJW30_RS06465 | 1338727..1340139 | - | 1413 | WP_096353176.1 | threonine synthase | - |
GJW30_RS06470 | 1340249..1340506 | + | 258 | WP_096358694.1 | antitoxin | Antitoxin |
GJW30_RS06475 | 1340503..1340910 | + | 408 | WP_096353179.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
GJW30_RS06480 | 1340907..1341644 | - | 738 | WP_096353182.1 | SURF1 family protein | - |
GJW30_RS06485 | 1341644..1342030 | - | 387 | WP_096353185.1 | DUF983 domain-containing protein | - |
GJW30_RS06490 | 1342114..1342971 | - | 858 | WP_096353187.1 | cytochrome c oxidase subunit 3 | - |
GJW30_RS06495 | 1342995..1343591 | - | 597 | WP_096353190.1 | cytochrome c oxidase assembly protein | - |
GJW30_RS06500 | 1343602..1343769 | - | 168 | WP_172887556.1 | hypothetical protein | - |
GJW30_RS06505 | 1343781..1344719 | - | 939 | WP_096353196.1 | heme o synthase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 136 a.a. Molecular weight: 14860.28 Da Isoelectric Point: 10.0298
>T31033 WP_096353179.1 NZ_AP014946:1340503-1340910 [Variibacter gotjawalensis]
MIQHFLDTNAAITLMNYRPGRLFARVAAAPEKSVAVSALVVHELLYGAMRSAKIELNLKRIRLFLTDIPVFPFDAEDARV
AGEVRAVLAARGTPIGPYDALIAAQAKVRNLTVITNNVREFSRVDGLRIEDWSAA
MIQHFLDTNAAITLMNYRPGRLFARVAAAPEKSVAVSALVVHELLYGAMRSAKIELNLKRIRLFLTDIPVFPFDAEDARV
AGEVRAVLAARGTPIGPYDALIAAQAKVRNLTVITNNVREFSRVDGLRIEDWSAA
Download Length: 408 bp
>T31033 NZ_AP014946:1340503-1340910 [Variibacter gotjawalensis]
ATGATCCAGCATTTTCTCGATACGAACGCCGCCATCACGCTCATGAACTATCGACCTGGTCGATTGTTTGCTCGCGTTGC
CGCCGCTCCCGAAAAATCCGTCGCCGTATCCGCGCTCGTCGTGCACGAACTTCTCTATGGCGCGATGCGGAGCGCGAAGA
TCGAGCTGAACCTTAAGCGCATTCGGCTTTTCTTGACCGACATCCCTGTCTTCCCGTTCGATGCCGAGGATGCGCGTGTC
GCTGGCGAGGTCCGTGCGGTTTTGGCGGCGCGCGGCACGCCAATAGGACCCTACGACGCGCTCATCGCGGCGCAAGCAAA
GGTCCGCAATCTCACCGTCATCACCAACAACGTCCGCGAATTCTCACGCGTCGACGGTTTGCGCATCGAAGACTGGAGCG
CGGCTTAA
ATGATCCAGCATTTTCTCGATACGAACGCCGCCATCACGCTCATGAACTATCGACCTGGTCGATTGTTTGCTCGCGTTGC
CGCCGCTCCCGAAAAATCCGTCGCCGTATCCGCGCTCGTCGTGCACGAACTTCTCTATGGCGCGATGCGGAGCGCGAAGA
TCGAGCTGAACCTTAAGCGCATTCGGCTTTTCTTGACCGACATCCCTGTCTTCCCGTTCGATGCCGAGGATGCGCGTGTC
GCTGGCGAGGTCCGTGCGGTTTTGGCGGCGCGCGGCACGCCAATAGGACCCTACGACGCGCTCATCGCGGCGCAAGCAAA
GGTCCGCAATCTCACCGTCATCACCAACAACGTCCGCGAATTCTCACGCGTCGACGGTTTGCGCATCGAAGACTGGAGCG
CGGCTTAA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9637.67 Da Isoelectric Point: 4.5098
>AT31033 WP_096358694.1 NZ_AP014946:1340249-1340506 [Variibacter gotjawalensis]
VPRTAKIFQSGNSQAVRLPKDFRFDVSEVEISRDGDAVILRPVQTREPWAGLKAAQALGFDETFSPNGREQPEEQHRPEL
DDLFE
VPRTAKIFQSGNSQAVRLPKDFRFDVSEVEISRDGDAVILRPVQTREPWAGLKAAQALGFDETFSPNGREQPEEQHRPEL
DDLFE
Download Length: 258 bp
>AT31033 NZ_AP014946:1340249-1340506 [Variibacter gotjawalensis]
GTGCCGCGTACCGCCAAAATCTTCCAATCCGGCAATTCGCAAGCCGTCCGTCTGCCGAAGGATTTTCGCTTCGACGTCAG
CGAAGTCGAGATCTCGCGCGATGGCGACGCTGTGATTCTGCGCCCGGTGCAGACACGCGAGCCATGGGCTGGACTTAAAG
CCGCGCAAGCGCTTGGATTTGACGAAACCTTTTCCCCCAATGGACGCGAACAGCCGGAAGAGCAGCATCGTCCCGAGCTC
GACGACCTGTTTGAATGA
GTGCCGCGTACCGCCAAAATCTTCCAATCCGGCAATTCGCAAGCCGTCCGTCTGCCGAAGGATTTTCGCTTCGACGTCAG
CGAAGTCGAGATCTCGCGCGATGGCGACGCTGTGATTCTGCGCCCGGTGCAGACACGCGAGCCATGGGCTGGACTTAAAG
CCGCGCAAGCGCTTGGATTTGACGAAACCTTTTCCCCCAATGGACGCGAACAGCCGGAAGAGCAGCATCGTCCCGAGCTC
GACGACCTGTTTGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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