Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1340249..1340910 Replicon chromosome
Accession NZ_AP014946
Organism Variibacter gotjawalensis strain GJW-30

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GJW30_RS06475 Protein ID WP_096353179.1
Coordinates 1340503..1340910 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag GJW30_RS06470 Protein ID WP_096358694.1
Coordinates 1340249..1340506 (+) Length 86 a.a.

Genomic Context

GJW30_RS06470GJW30_RS06475GJW30_RS06450GJW30_RS06455GJW30_RS06460GJW30_RS06465GJW30_RS06480GJW30_RS06485GJW30_RS06490GJW30_RS06495GJW30_RS06500GJW30_RS06505
Location: 1340249..1340506 (258 bp)
Type: Antitoxin
Protein ID: WP_096358694.1
Location: 1340503..1340910 (408 bp)
Type: Toxin
Protein ID: WP_096353179.1
Location: 1336117..1336761 (645 bp)
Type: Others
Protein ID: WP_130364777.1
Location: 1336859..1337446 (588 bp)
Type: Others
Protein ID: WP_096353172.1
Location: 1337459..1338730 (1272 bp)
Type: Others
Protein ID: WP_096353174.1
Location: 1338727..1340139 (1413 bp)
Type: Others
Protein ID: WP_096353176.1
Location: 1340907..1341644 (738 bp)
Type: Others
Protein ID: WP_096353182.1
Location: 1341644..1342030 (387 bp)
Type: Others
Protein ID: WP_096353185.1
Location: 1342114..1342971 (858 bp)
Type: Others
Protein ID: WP_096353187.1
Location: 1342995..1343591 (597 bp)
Type: Others
Protein ID: WP_096353190.1
Location: 1343602..1343769 (168 bp)
Type: Others
Protein ID: WP_172887556.1
Location: 1343781..1344719 (939 bp)
Type: Others
Protein ID: WP_096353196.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GJW30_RS064501336117..1336761-645WP_130364777.1hypothetical protein-
GJW30_RS064551336859..1337446-588WP_096353172.1GNAT family N-acetyltransferase-
GJW30_RS064601337459..1338730-1272WP_096353174.1insulinase family protein-
GJW30_RS064651338727..1340139-1413WP_096353176.1threonine synthase-
GJW30_RS064701340249..1340506+258WP_096358694.1antitoxinAntitoxin
GJW30_RS064751340503..1340910+408WP_096353179.1type II toxin-antitoxin system VapC family toxinToxin
GJW30_RS064801340907..1341644-738WP_096353182.1SURF1 family protein-
GJW30_RS064851341644..1342030-387WP_096353185.1DUF983 domain-containing protein-
GJW30_RS064901342114..1342971-858WP_096353187.1cytochrome c oxidase subunit 3-
GJW30_RS064951342995..1343591-597WP_096353190.1cytochrome c oxidase assembly protein-
GJW30_RS065001343602..1343769-168WP_172887556.1hypothetical protein-
GJW30_RS065051343781..1344719-939WP_096353196.1heme o synthase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-126)

Antitoxin

SpoVT-AbrB domain

(8-44)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14860.28 Da        Isoelectric Point: 10.0298

>T31033 WP_096353179.1 NZ_AP014946:1340503-1340910 [Variibacter gotjawalensis]
MIQHFLDTNAAITLMNYRPGRLFARVAAAPEKSVAVSALVVHELLYGAMRSAKIELNLKRIRLFLTDIPVFPFDAEDARV
AGEVRAVLAARGTPIGPYDALIAAQAKVRNLTVITNNVREFSRVDGLRIEDWSAA

Download         Length: 408 bp

>T31033 NZ_AP014946:1340503-1340910 [Variibacter gotjawalensis]
ATGATCCAGCATTTTCTCGATACGAACGCCGCCATCACGCTCATGAACTATCGACCTGGTCGATTGTTTGCTCGCGTTGC
CGCCGCTCCCGAAAAATCCGTCGCCGTATCCGCGCTCGTCGTGCACGAACTTCTCTATGGCGCGATGCGGAGCGCGAAGA
TCGAGCTGAACCTTAAGCGCATTCGGCTTTTCTTGACCGACATCCCTGTCTTCCCGTTCGATGCCGAGGATGCGCGTGTC
GCTGGCGAGGTCCGTGCGGTTTTGGCGGCGCGCGGCACGCCAATAGGACCCTACGACGCGCTCATCGCGGCGCAAGCAAA
GGTCCGCAATCTCACCGTCATCACCAACAACGTCCGCGAATTCTCACGCGTCGACGGTTTGCGCATCGAAGACTGGAGCG
CGGCTTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9637.67 Da        Isoelectric Point: 4.5098

>AT31033 WP_096358694.1 NZ_AP014946:1340249-1340506 [Variibacter gotjawalensis]
VPRTAKIFQSGNSQAVRLPKDFRFDVSEVEISRDGDAVILRPVQTREPWAGLKAAQALGFDETFSPNGREQPEEQHRPEL
DDLFE

Download         Length: 258 bp

>AT31033 NZ_AP014946:1340249-1340506 [Variibacter gotjawalensis]
GTGCCGCGTACCGCCAAAATCTTCCAATCCGGCAATTCGCAAGCCGTCCGTCTGCCGAAGGATTTTCGCTTCGACGTCAG
CGAAGTCGAGATCTCGCGCGATGGCGACGCTGTGATTCTGCGCCCGGTGCAGACACGCGAGCCATGGGCTGGACTTAAAG
CCGCGCAAGCGCTTGGATTTGACGAAACCTTTTCCCCCAATGGACGCGAACAGCCGGAAGAGCAGCATCGTCCCGAGCTC
GACGACCTGTTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References