Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT_toxin-BrnA
Location 994138..994687 Replicon chromosome
Accession NZ_AP014946
Organism Variibacter gotjawalensis strain GJW-30

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag GJW30_RS04770 Protein ID WP_096352324.1
Coordinates 994430..994687 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag GJW30_RS04765 Protein ID WP_096352322.1
Coordinates 994138..994446 (-) Length 103 a.a.

Genomic Context

GJW30_RS04750GJW30_RS04755GJW30_RS04760GJW30_RS04775GJW30_RS04780GJW30_RS04785GJW30_RS04740GJW30_RS04745GJW30_RS04765GJW30_RS04770GJW30_RS04790GJW30_RS04795GJW30_RS04800
Location: 992499..993188 (690 bp)
Type: Others
Protein ID: WP_096352313.1
Location: 993288..993836 (549 bp)
Type: Others
Protein ID: WP_096352316.1
Location: 993742..994131 (390 bp)
Type: Others
Protein ID: WP_096352319.1
Location: 994823..995176 (354 bp)
Type: Others
Protein ID: WP_096352328.1
Location: 995277..996647 (1371 bp)
Type: Others
Protein ID: WP_096352331.1
Location: 996815..997393 (579 bp)
Type: Others
Protein ID: WP_096352334.1
Location: 989175..991742 (2568 bp)
Type: Others
Protein ID: WP_096352308.1
Location: 991739..992449 (711 bp)
Type: Others
Protein ID: WP_096352310.1
Location: 994138..994446 (309 bp)
Type: Antitoxin
Protein ID: WP_096352322.1
Location: 994430..994687 (258 bp)
Type: Toxin
Protein ID: WP_096352324.1
Location: 997395..998828 (1434 bp)
Type: Others
Protein ID: WP_096352337.1
Location: 998761..999123 (363 bp)
Type: Others
Protein ID: WP_096358658.1
Location: 999216..999449 (234 bp)
Type: Others
Protein ID: WP_096352340.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GJW30_RS04740989175..991742-2568WP_096352308.1FtsX-like permease family protein-
GJW30_RS04745991739..992449-711WP_096352310.1ABC transporter ATP-binding protein-
GJW30_RS04750992499..993188+690WP_096352313.1arylesterase-
GJW30_RS04755993288..993836+549WP_096352316.1RNA 2',3'-cyclic phosphodiesterase-
GJW30_RS04760993742..994131+390WP_096352319.14a-hydroxytetrahydrobiopterin dehydratase-
GJW30_RS04765994138..994446-309WP_096352322.1BrnA antitoxin family proteinAntitoxin
GJW30_RS04770994430..994687-258WP_096352324.1BrnT family toxinToxin
GJW30_RS04775994823..995176+354WP_096352328.1DUF1232 domain-containing protein-
GJW30_RS04780995277..996647+1371WP_096352331.1glutamate--cysteine ligase-
GJW30_RS04785996815..997393+579WP_096352334.1LysE family transporter-
GJW30_RS04790997395..998828-1434WP_096352337.1chromate transporter-
GJW30_RS04795998761..999123-363WP_096358658.1metallopeptidase family protein-
GJW30_RS04800999216..999449-234WP_096352340.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-77)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(28-100)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9861.38 Da        Isoelectric Point: 10.2126

>T31032 WP_096352324.1 NZ_AP014946:c994687-994430 [Variibacter gotjawalensis]
MQIVWDEPKRLKNLLTHRLDFADLRIDFFLTADIRPSYAGRATATGVFESTMITVVFSRLGSEAISLISMRHSSRKERRL
YEKEA

Download         Length: 258 bp

>T31032 NZ_AP014946:c994687-994430 [Variibacter gotjawalensis]
ATGCAGATCGTTTGGGACGAGCCGAAGCGGCTCAAGAATTTACTGACCCATAGGCTGGATTTTGCGGACCTGCGGATCGA
TTTTTTCCTTACCGCCGACATCCGGCCGAGCTACGCGGGTCGCGCCACAGCCACCGGCGTGTTTGAGAGCACGATGATCA
CGGTCGTGTTCTCGAGACTCGGGAGCGAGGCGATCTCGCTGATCTCGATGCGCCATTCGAGTAGGAAGGAGCGGAGGCTC
TATGAAAAAGAAGCTTGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11759.46 Da        Isoelectric Point: 10.4136

>AT31032 WP_096352322.1 NZ_AP014946:c994446-994138 [Variibacter gotjawalensis]
MKKKLDHLRPLTDAEEARIQRGIAEDPENPEWTEQDFKTARPFAEVFPELAESIRRARGRPPVETPRQQISIRLDPDVIA
KFKATGKGWQSRINDVLKKAKV

Download         Length: 309 bp

>AT31032 NZ_AP014946:c994446-994138 [Variibacter gotjawalensis]
ATGAAAAAGAAGCTTGATCATTTGAGGCCTCTCACCGACGCCGAAGAAGCACGCATCCAGCGCGGGATCGCGGAAGATCC
AGAGAATCCCGAGTGGACCGAGCAGGACTTCAAAACCGCGCGCCCATTCGCCGAAGTCTTCCCCGAGCTCGCCGAAAGCA
TCCGGCGCGCGCGCGGGAGGCCACCGGTCGAGACGCCGCGTCAGCAGATTTCGATCCGGCTCGATCCCGACGTCATCGCG
AAATTCAAGGCGACCGGCAAAGGCTGGCAGTCGCGCATCAACGATGTGCTGAAGAAGGCGAAGGTGTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References