Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-VagC |
Location | 495066..495730 | Replicon | chromosome |
Accession | NZ_AP014946 | ||
Organism | Variibacter gotjawalensis strain GJW-30 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | GJW30_RS02395 | Protein ID | WP_096351177.1 |
Coordinates | 495323..495730 (+) | Length | 136 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | GJW30_RS02390 | Protein ID | WP_197703761.1 |
Coordinates | 495066..495326 (+) | Length | 87 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GJW30_RS02360 | 490181..490831 | - | 651 | WP_096351165.1 | CoA transferase subunit B | - |
GJW30_RS02365 | 490844..491545 | - | 702 | WP_096351167.1 | CoA transferase subunit A | - |
GJW30_RS02370 | 491791..492183 | - | 393 | WP_096351168.1 | Co2+/Mg2+ efflux protein ApaG | - |
GJW30_RS02375 | 492297..493502 | + | 1206 | WP_096351170.1 | OpgC domain-containing protein | - |
GJW30_RS02380 | 493499..494248 | + | 750 | WP_096351171.1 | SGNH/GDSL hydrolase family protein | - |
GJW30_RS02385 | 494245..495021 | + | 777 | WP_096351173.1 | SGNH/GDSL hydrolase family protein | - |
GJW30_RS02390 | 495066..495326 | + | 261 | WP_197703761.1 | antitoxin | Antitoxin |
GJW30_RS02395 | 495323..495730 | + | 408 | WP_096351177.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
GJW30_RS02400 | 495731..496903 | - | 1173 | WP_096351180.1 | O-succinylhomoserine sulfhydrylase | - |
GJW30_RS02405 | 497274..498329 | + | 1056 | WP_197703797.1 | 2'-deoxycytidine 5'-triphosphate deaminase | - |
GJW30_RS02410 | 498378..499196 | - | 819 | WP_096351184.1 | ion transporter | - |
GJW30_RS02415 | 499313..500119 | - | 807 | WP_096358613.1 | ion transporter | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 136 a.a. Molecular weight: 14988.22 Da Isoelectric Point: 9.2587
>T31031 WP_096351177.1 NZ_AP014946:495323-495730 [Variibacter gotjawalensis]
MTAPRFVLDTNTVSDLVKNPQGRVAQRLAEIGADGICVSLIVAAELRYGCAKRASMRLTERVEGVLSRLHVLPLTAPVDR
EYAEIRTDAERTGRNIGPNDLWIAAHARSLGVPLVTANEREFRTVRGLNIENWLR
MTAPRFVLDTNTVSDLVKNPQGRVAQRLAEIGADGICVSLIVAAELRYGCAKRASMRLTERVEGVLSRLHVLPLTAPVDR
EYAEIRTDAERTGRNIGPNDLWIAAHARSLGVPLVTANEREFRTVRGLNIENWLR
Download Length: 408 bp
>T31031 NZ_AP014946:495323-495730 [Variibacter gotjawalensis]
TTGACGGCTCCTCGATTCGTTCTCGATACGAATACGGTTTCTGACCTCGTCAAAAACCCGCAGGGTCGTGTCGCTCAACG
ACTGGCAGAGATCGGAGCGGACGGCATTTGTGTAAGCCTCATCGTGGCCGCCGAATTAAGGTACGGCTGCGCAAAGCGCG
CATCAATGCGGTTGACCGAGCGTGTCGAAGGTGTGCTTAGCCGCCTACATGTACTCCCACTGACTGCGCCGGTTGATCGC
GAATATGCCGAGATCAGAACCGACGCCGAGCGAACAGGACGAAACATCGGCCCTAACGATCTTTGGATCGCTGCACATGC
ACGTTCCCTCGGTGTCCCATTGGTCACCGCAAACGAACGAGAGTTTCGAACCGTTCGCGGACTAAACATCGAAAATTGGC
TGCGCTGA
TTGACGGCTCCTCGATTCGTTCTCGATACGAATACGGTTTCTGACCTCGTCAAAAACCCGCAGGGTCGTGTCGCTCAACG
ACTGGCAGAGATCGGAGCGGACGGCATTTGTGTAAGCCTCATCGTGGCCGCCGAATTAAGGTACGGCTGCGCAAAGCGCG
CATCAATGCGGTTGACCGAGCGTGTCGAAGGTGTGCTTAGCCGCCTACATGTACTCCCACTGACTGCGCCGGTTGATCGC
GAATATGCCGAGATCAGAACCGACGCCGAGCGAACAGGACGAAACATCGGCCCTAACGATCTTTGGATCGCTGCACATGC
ACGTTCCCTCGGTGTCCCATTGGTCACCGCAAACGAACGAGAGTTTCGAACCGTTCGCGGACTAAACATCGAAAATTGGC
TGCGCTGA
Antitoxin
Download Length: 87 a.a. Molecular weight: 9785.27 Da Isoelectric Point: 4.4978
>AT31031 WP_197703761.1 NZ_AP014946:495066-495326 [Variibacter gotjawalensis]
MPNRCMANVQSRHVKLFRNNRNQAVRIPVEFELPGDEAIITRDGDKLIIEPVKKSGLLAYLATLEPLDEDFPDVDESLLP
LKDIEL
MPNRCMANVQSRHVKLFRNNRNQAVRIPVEFELPGDEAIITRDGDKLIIEPVKKSGLLAYLATLEPLDEDFPDVDESLLP
LKDIEL
Download Length: 261 bp
>AT31031 NZ_AP014946:495066-495326 [Variibacter gotjawalensis]
ATGCCAAACAGGTGTATGGCAAATGTCCAGAGTCGTCATGTCAAACTTTTCAGAAATAACCGCAATCAAGCGGTGCGGAT
TCCGGTTGAGTTCGAACTCCCGGGAGACGAGGCCATCATCACGCGCGACGGCGACAAGCTGATCATCGAGCCGGTGAAAA
AGTCTGGGTTGCTTGCCTATCTGGCAACACTCGAACCTCTCGATGAGGATTTTCCAGATGTCGACGAGAGTCTGCTACCG
CTCAAGGATATAGAGCTTTGA
ATGCCAAACAGGTGTATGGCAAATGTCCAGAGTCGTCATGTCAAACTTTTCAGAAATAACCGCAATCAAGCGGTGCGGAT
TCCGGTTGAGTTCGAACTCCCGGGAGACGAGGCCATCATCACGCGCGACGGCGACAAGCTGATCATCGAGCCGGTGAAAA
AGTCTGGGTTGCTTGCCTATCTGGCAACACTCGAACCTCTCGATGAGGATTTTCCAGATGTCGACGAGAGTCTGCTACCG
CTCAAGGATATAGAGCTTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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