Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 470074..470662 Replicon chromosome
Accession NZ_AP014946
Organism Variibacter gotjawalensis strain GJW-30

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GJW30_RS02260 Protein ID WP_096351119.1
Coordinates 470372..470662 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GJW30_RS02255 Protein ID WP_197703795.1
Coordinates 470074..470361 (-) Length 96 a.a.

Genomic Context

GJW30_RS02250GJW30_RS02280GJW30_RS02285GJW30_RS02235GJW30_RS02240GJW30_RS02245GJW30_RS02255GJW30_RS02260GJW30_RS02265GJW30_RS02270GJW30_RS02275
Location: 468773..470077 (1305 bp)
Type: Others
Protein ID: WP_096351113.1
Location: 473502..474359 (858 bp)
Type: Others
Protein ID: WP_096351128.1
Location: 474390..475199 (810 bp)
Type: Others
Protein ID: WP_096351130.1
Location: 465198..466010 (813 bp)
Type: Others
Protein ID: WP_096351104.1
Location: 466123..467352 (1230 bp)
Type: Others
Protein ID: WP_096351107.1
Location: 467419..468597 (1179 bp)
Type: Others
Protein ID: WP_096351110.1
Location: 470074..470361 (288 bp)
Type: Antitoxin
Protein ID: WP_197703795.1
Location: 470372..470662 (291 bp)
Type: Toxin
Protein ID: WP_096351119.1
Location: 470715..471482 (768 bp)
Type: Others
Protein ID: WP_096358609.1
Location: 471491..472264 (774 bp)
Type: Others
Protein ID: WP_157746675.1
Location: 472254..473225 (972 bp)
Type: Others
Protein ID: WP_096351125.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GJW30_RS02235465198..466010-813WP_096351104.1transglycosylase SLT domain-containing protein-
GJW30_RS02240466123..467352-1230WP_096351107.1FAD-dependent oxidoreductase-
GJW30_RS02245467419..468597-1179WP_096351110.14-hydroxybenzoate 3-monooxygenase-
GJW30_RS02250468773..470077+1305WP_096351113.1nicotinate phosphoribosyltransferase-
GJW30_RS02255470074..470361-288WP_197703795.1putative addiction module antidote proteinAntitoxin
GJW30_RS02260470372..470662-291WP_096351119.1type II toxin-antitoxin system RelE/ParE family toxinToxin
GJW30_RS02265470715..471482-768WP_096358609.1ATP-binding cassette domain-containing protein-
GJW30_RS02270471491..472264-774WP_157746675.1ABC transporter permease subunit-
GJW30_RS02275472254..473225-972WP_096351125.1ABC transporter substrate-binding protein-
GJW30_RS02280473502..474359+858WP_096351128.1alpha/beta hydrolase-
GJW30_RS02285474390..475199+810WP_096351130.1SDR family NAD(P)-dependent oxidoreductase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-92)

Antitoxin

Uncharacterized protein HI1420

(2-89)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11096.86 Da        Isoelectric Point: 9.9208

>T31030 WP_096351119.1 NZ_AP014946:c470662-470372 [Variibacter gotjawalensis]
MFEVVQTERFTDWLDHLKEFTAAVRIITKLRRIELGNLGDAKSVGEGVSELRIDYGPGYRIYFTQRGRKLIVLLCGGDKK
SQRRDIELAQRIAKEI

Download         Length: 291 bp

>T31030 NZ_AP014946:c470662-470372 [Variibacter gotjawalensis]
ATGTTCGAGGTCGTCCAAACCGAGCGTTTCACGGATTGGCTCGACCACCTCAAGGAATTCACAGCAGCCGTTCGCATCAT
CACGAAGCTTCGTCGCATCGAACTCGGAAATCTGGGCGACGCGAAGTCAGTCGGCGAAGGTGTGAGCGAGCTTCGCATCG
ACTACGGGCCTGGCTATCGCATCTACTTCACACAGCGCGGCCGGAAGCTCATCGTTTTGCTCTGTGGCGGGGACAAAAAA
TCGCAGCGGCGCGATATCGAACTCGCTCAGCGCATCGCGAAGGAGATCTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10264.87 Da        Isoelectric Point: 10.4670

>AT31030 WP_197703795.1 NZ_AP014946:c470361-470074 [Variibacter gotjawalensis]
MKTTKFDVQHHLKTIKQQIAYLEAALDEDDATFIAAALGDVAKARGVTAFARETGLSREAIYKAFRPGGNPTIETVNKAL
RALGLRLKLAPARAA

Download         Length: 288 bp

>AT31030 NZ_AP014946:c470361-470074 [Variibacter gotjawalensis]
TTGAAGACCACGAAATTCGACGTTCAGCATCATCTTAAGACGATCAAACAACAGATCGCCTATCTCGAAGCGGCGCTGGA
CGAAGACGATGCGACCTTTATCGCTGCTGCGCTCGGCGACGTCGCGAAAGCGCGCGGCGTGACGGCCTTTGCGCGCGAGA
CGGGACTGAGCCGCGAGGCGATCTACAAAGCGTTTCGTCCCGGCGGAAATCCGACAATCGAGACTGTCAACAAAGCGCTG
CGGGCACTCGGCCTTCGGTTGAAGCTCGCGCCGGCTAGAGCGGCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References