Detailed information of TA system TA031029

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-Xre
• Location: 288684..289534
• Replicon: chromosome
• Accession: NZ_AP014946
• Organism: Variibacter gotjawalensis strain GJW-30

Toxin (Protein)

• Gene name: slvT
• Uniprot ID: -
• Locus tag: GJW30_RS01310
• Protein ID: WP_096350727.1
• Coordinates: 288684..289202 (-)
• Length: 173 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: GJW30_RS01315
• Protein ID: WP_165391634.1
• Coordinates: 289199..289534 (-)
• Length: 112 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GJW30_RS01280	284220..285200	+	981	WP_096350719.1	alpha/beta hydrolase	-
GJW30_RS01285	285347..286126	-	780	WP_096350721.1	histidinol-phosphatase	-
GJW30_RS01290	286602..287492	-	891	WP_096350723.1	N-formylglutamate amidohydrolase	-
GJW30_RS01295	287654..288013	+	360	WP_096350725.1	response regulator	-
GJW30_RS01305	288353..288676	+	324	WP_096358587.1	quaternary ammonium compound efflux SMR transporter SugE	-
GJW30_RS01310	288684..289202	-	519	WP_096350727.1	RES family NAD+ phosphorylase	Toxin
GJW30_RS01315	289199..289534	-	336	WP_165391634.1	DUF2384 domain-containing protein	Antitoxin
GJW30_RS01320	289785..289910	+	126	WP_096350731.1	type B 50S ribosomal protein L36	-
GJW30_RS01325	290019..290645	+	627	WP_096350733.1	hypothetical protein	-
GJW30_RS01330	290789..292225	-	1437	WP_096350735.1	pyruvate kinase	-
GJW30_RS01335	292222..292731	-	510	WP_096350737.1	DUF1036 domain-containing protein	-
GJW30_RS01340	292747..294045	-	1299	WP_096350740.1	glycerate kinase	-
GJW30_RS01345	294209..294505	+	297	WP_096350743.1	DUF1244 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (7-167)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (8-41)

Sequences

Toxin

Protein

• Length: 173 a.a.
• Molecular weight: 18853.55 Da
• Isoelectric Point: 7.7009

>T31029 WP_096350727.1 NZ_AP014946:c289202-288684 [Variibacter gotjawalensis]
MRFVGVCYRAHDPRWAFSPTSGSGAAIRGARFNPKGVPALYLALNIVTAVKEASQGLAHRIDPLTLCAYEVDCDPIADLT
AEEQRALYGVEANDMKCAWAAELAEGKRPASWSIHDQLVAQGVAGIRVPSFAPGADANDVNLVLWMWGPALPRQVRVIDP
RFRLPRDQSSWR

Nucleotide

• Length: 519 bp

>T31029 NZ_AP014946:c289202-288684 [Variibacter gotjawalensis]
TTGAGGTTCGTCGGCGTTTGCTACCGAGCGCACGATCCTCGATGGGCATTCAGCCCGACTTCTGGATCCGGAGCCGCAAT
CAGGGGCGCGCGCTTCAATCCCAAAGGAGTGCCCGCACTCTATCTGGCGCTGAACATAGTCACGGCGGTGAAGGAAGCGA
GCCAGGGGTTGGCACACCGCATCGATCCGCTGACGCTGTGCGCTTACGAAGTCGACTGCGATCCCATCGCTGACCTAACA
GCCGAGGAGCAGCGAGCGCTCTACGGCGTCGAAGCCAACGATATGAAATGTGCCTGGGCTGCCGAGCTTGCCGAGGGCAA
GCGTCCGGCTTCTTGGTCTATTCACGACCAGCTCGTTGCACAGGGAGTTGCTGGAATTCGCGTGCCAAGTTTCGCGCCTG
GAGCCGACGCCAATGACGTCAATCTCGTGCTCTGGATGTGGGGACCGGCCTTGCCGCGCCAGGTCAGGGTCATCGACCCG
CGTTTTCGACTACCACGCGACCAATCTTCCTGGCGCTAG

Antitoxin

Protein

• Length: 112 a.a.
• Molecular weight: 11974.64 Da
• Isoelectric Point: 9.6205

>AT31029 WP_165391634.1 NZ_AP014946:c289534-289199 [Variibacter gotjawalensis]
MDSSGQIAATRVVDRFGISKTQLAETIGLPRETLYRAERSGATKAQARLREVLEILSLVSEWAGGPQQALAWYRAQPIPA
FGERTAAAVVKEGKASAVRDYLDHMALGGFA

Nucleotide

• Length: 336 bp

>AT31029 NZ_AP014946:c289534-289199 [Variibacter gotjawalensis]
ATGGACAGCAGCGGGCAAATCGCCGCTACCCGCGTCGTTGACCGCTTCGGCATCTCCAAGACGCAACTGGCTGAAACGAT
CGGCTTGCCGCGGGAGACGCTTTACCGGGCCGAGCGCAGTGGCGCGACCAAAGCGCAGGCGCGCTTGCGCGAAGTGCTGG
AGATTCTTTCGCTTGTGTCTGAGTGGGCAGGCGGGCCGCAACAAGCCTTGGCTTGGTATCGCGCTCAGCCGATCCCGGCT
TTCGGCGAGCGTACGGCGGCGGCGGTCGTCAAAGAGGGCAAGGCGTCAGCCGTCCGAGACTATTTAGATCATATGGCTCT
CGGCGGGTTTGCTTGA