31028

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 253782..254320 Replicon chromosome
Accession NZ_AP014946
Organism Variibacter gotjawalensis strain GJW-30

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag GJW30_RS01175 Protein ID WP_096350673.1
Coordinates 254030..254320 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag GJW30_RS01170 Protein ID WP_096350670.1
Coordinates 253782..254033 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GJW30_RS01140 248992..249366 + 375 WP_096350658.1 DUF423 domain-containing protein -
GJW30_RS01145 249345..250907 - 1563 WP_197703759.1 alkaline phosphatase family protein -
GJW30_RS01150 251430..252056 + 627 WP_096350662.1 TetR/AcrR family transcriptional regulator -
GJW30_RS01155 252146..253033 + 888 WP_096350664.1 acetylglutamate kinase -
GJW30_RS01160 253056..253313 + 258 WP_096350666.1 hypothetical protein -
GJW30_RS01165 253279..253719 - 441 WP_096350668.1 gamma-glutamylcyclotransferase -
GJW30_RS01170 253782..254033 + 252 WP_096350670.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
GJW30_RS01175 254030..254320 + 291 WP_096350673.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GJW30_RS01180 254326..256740 - 2415 WP_096350675.1 PBP1A family penicillin-binding protein -
GJW30_RS01185 256887..257285 - 399 WP_096350677.1 5-carboxymethyl-2-hydroxymuconate Delta-isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(5-72)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11195.81 Da        Isoelectric Point: 9.6860

>T31028 WP_096350673.1 NZ_AP014946:254030-254320 [Variibacter gotjawalensis]
MKLYVLSPRARDDLRAIWKFTAERWSVDQAERYTRQIQQAIETVSADPAAGRSCDLIRAGYRKFPAGSNVIFFRETPDAI
DIVRILHARMDFERHL

Download         Length: 291 bp

>T31028 NZ_AP014946:254030-254320 [Variibacter gotjawalensis]
ATGAAACTGTACGTTTTATCGCCGCGAGCACGCGACGATTTGCGAGCGATTTGGAAATTTACAGCCGAGCGATGGAGCGT
CGATCAAGCCGAGCGCTACACGCGACAGATTCAACAAGCGATTGAAACAGTCTCCGCAGACCCGGCTGCAGGCCGTTCAT
GCGACCTCATTCGGGCCGGCTACCGAAAATTTCCGGCTGGATCTAACGTGATCTTCTTTCGCGAGACGCCCGATGCGATC
GACATCGTACGCATACTGCACGCACGGATGGATTTCGAACGTCATCTTTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9162.14 Da        Isoelectric Point: 5.6939

>AT31028 WP_096350670.1 NZ_AP014946:253782-254033 [Variibacter gotjawalensis]
MGKHTSFSLGDHFATFIDEQIAQGRYSNASDVVRAGLRLLEEQEAKLASLRSALIEGENSGASTPFDFDEFIAGQRKGET
RRK

Download         Length: 252 bp

>AT31028 NZ_AP014946:253782-254033 [Variibacter gotjawalensis]
ATGGGCAAACACACGTCTTTCAGCCTTGGTGACCATTTCGCCACCTTCATCGACGAGCAAATTGCGCAGGGTCGTTATAG
CAACGCGAGCGACGTCGTTCGCGCCGGCCTGCGCCTGTTGGAAGAGCAAGAAGCAAAACTTGCTAGTCTCCGAAGCGCAT
TGATCGAAGGCGAGAATAGCGGAGCATCGACACCGTTCGATTTCGACGAATTCATCGCCGGACAGCGCAAGGGTGAAACG
CGCCGCAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References