31016

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 830432..830909 Replicon chromosome
Accession NZ_AP014942
Organism Staphylococcus aureus strain FDA209P

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag SAFDA_RS04000 Protein ID WP_000052076.1
Coordinates 830432..830620 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag SAFDA_RS04005 Protein ID WP_001059690.1
Coordinates 830649..830909 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAFDA_RS03970 826474..826944 + 471 WP_000824472.1 hypothetical protein -
SAFDA_RS03975 827285..827971 + 687 WP_001548082.1 thermonuclease family protein -
SAFDA_RS03980 828328..828528 + 201 WP_001059082.1 cold-shock protein -
SAFDA_RS03985 829023..829241 - 219 WP_000005884.1 hypothetical protein -
SAFDA_RS03990 829303..829587 - 285 WP_001004394.1 hypothetical protein -
SAFDA_RS03995 829675..830244 - 570 WP_001106653.1 hypothetical protein -
SAFDA_RS04000 830432..830620 - 189 WP_000052076.1 hypothetical protein Toxin
SAFDA_RS04005 830649..830909 - 261 WP_001059690.1 hypothetical protein Antitoxin
SAFDA_RS04010 831250..831453 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
SAFDA_RS04015 831450..831686 - 237 WP_000368687.1 hypothetical protein -
SAFDA_RS04020 831911..832492 + 582 WP_001140697.1 phosphoglycerate mutase family protein -
SAFDA_RS04025 832565..833182 - 618 WP_000255553.1 LysE/ArgO family amino acid transporter -
SAFDA_RS04030 833337..833831 - 495 WP_000569884.1 GNAT family N-acetyltransferase -
SAFDA_RS04035 834230..834652 - 423 WP_000974460.1 organic hydroperoxide resistance protein -
SAFDA_RS04040 834800..835516 + 717 WP_000150013.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - clfA / vWbp / selk / selq 812555..857509 44954


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T31016 WP_000052076.1 NZ_AP014942:c830620-830432 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

>T31016 NZ_AP014942:c830620-830432 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT31016 WP_001059690.1 NZ_AP014942:c830909-830649 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp

>AT31016 NZ_AP014942:c830909-830649 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATCGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTATATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References