Detailed information of TA system TA030998

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/LOTUS_5_Limkain_b1-VagC
• Location: 20929..21593
• Replicon: plasmid plasmid1 DNA
• Accession: NZ_AP014882
• Organism: Acetobacter pasteurianus NBRC 101655

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: A0A2G4REI9
• Locus tag: APT_RS13450
• Protein ID: WP_035362716.1
• Coordinates: 21183..21593 (+)
• Length: 137 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: APT_RS13445
• Protein ID: WP_035362726.1
• Coordinates: 20929..21186 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
APT_RS13405	16161..16736	-	576	WP_003626726.1	MucR family transcriptional regulator	-
APT_RS13410	16860..17138	-	279	WP_003626728.1	hypothetical protein	-
APT_RS13415	17168..17428	+	261	WP_040133426.1	hypothetical protein	-
APT_RS13420	17580..17888	-	309	WP_035362714.1	hypothetical protein	-
APT_RS13425	18121..18423	+	303	WP_003626733.1	hypothetical protein	-
APT_RS13430	19437..19925	+	489	Protein_14	single-stranded DNA-binding protein	-
APT_RS13435	19988..20428	+	441	WP_003626739.1	hypothetical protein	-
APT_RS13440	20425..20841	+	417	WP_003626740.1	hypothetical protein	-
APT_RS13445	20929..21186	+	258	WP_035362726.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
APT_RS13450	21183..21593	+	411	WP_035362716.1	type II toxin-antitoxin system VapC family toxin	Toxin
APT_RS13455	21730..22194	+	465	WP_020936773.1	hypothetical protein	-
APT_RS13460	22191..22391	+	201	WP_006560470.1	hypothetical protein	-
APT_RS14575	22519..22731	+	213	WP_003626743.1	hypothetical protein	-
APT_RS13465	22981..23334	-	354	WP_003626745.1	hypothetical protein	-
APT_RS13470	23394..24197	-	804	WP_003626746.1	hypothetical protein	-
APT_RS13475	24294..24758	-	465	WP_020936768.1	hypothetical protein	-
APT_RS13480	24761..25609	-	849	WP_035362718.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..187193	187193

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Protein of unknown function DUF1474 (1-100)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 137 a.a.
• Molecular weight: 17577.87 Da
• Isoelectric Point: 12.9335

>T30998 WP_035362716.1 NZ_AP014882:21183-21593 [Acetobacter pasteurianus NBRC 101655]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 411 bp

>T30998 NZ_AP014882:21183-21593 [Acetobacter pasteurianus NBRC 101655]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 11040.99 Da
• Isoelectric Point: 12.7294

>AT30998 WP_035362726.1 NZ_AP014882:20929-21186 [Acetobacter pasteurianus NBRC 101655]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKK

Nucleotide

• Length: 258 bp

>AT30998 NZ_AP014882:20929-21186 [Acetobacter pasteurianus NBRC 101655]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAA

Structures

Toxin

• AlphaFold DB: A0A2G4REI9