Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1433551..1434122 Replicon chromosome
Accession NZ_AP014879
Organism Sulfuricaulis limicola strain HA5

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag SCL_RS07095 Protein ID WP_197702759.1
Coordinates 1433838..1434122 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag SCL_RS07090 Protein ID WP_096360570.1
Coordinates 1433551..1433841 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SCL_RS07055 1429167..1429502 + 336 WP_148665023.1 hypothetical protein -
SCL_RS07060 1429805..1430113 + 309 WP_197702742.1 hypothetical protein -
SCL_RS07065 1430263..1430673 - 411 WP_197702743.1 heat-shock protein -
SCL_RS07070 1430680..1431789 - 1110 WP_197702744.1 Fic family protein -
SCL_RS07075 1431931..1432155 - 225 WP_096360568.1 hypothetical protein -
SCL_RS07080 1432421..1432819 + 399 WP_096360569.1 hypothetical protein -
SCL_RS14260 1433007..1433168 - 162 WP_172425960.1 hypothetical protein -
SCL_RS07085 1433234..1433479 - 246 WP_096361889.1 DNA-binding transcriptional regulator -
SCL_RS07090 1433551..1433841 - 291 WP_096360570.1 putative addiction module antidote protein Antitoxin
SCL_RS07095 1433838..1434122 - 285 WP_197702759.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SCL_RS07100 1434604..1436091 - 1488 WP_096360572.1 YdiU family protein -
SCL_RS14030 1436278..1436811 - 534 WP_148665024.1 hypothetical protein -
SCL_RS07105 1436904..1437701 - 798 WP_096360573.1 putative phage abortive infection protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(7-84)

Antitoxin

Uncharacterized protein HI1420

(10-92)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10804.64 Da        Isoelectric Point: 10.1808

>T30997 WP_197702759.1 NZ_AP014879:c1434122-1433838 [Sulfuricaulis limicola]
IVPFDRWIAKLRDPRAKARILVQLNRLALGLPGDWKPVGEGVCELRIFVGMGYRVFFAHDGKTVVVLLCGGDKSTQDRDI
ELAKSYWREYRKQT

Download         Length: 285 bp

>T30997 NZ_AP014879:c1434122-1433838 [Sulfuricaulis limicola]
ATTGTTCCGTTTGATCGTTGGATTGCGAAACTGCGCGATCCACGCGCCAAGGCTCGGATTCTCGTACAACTTAACCGCCT
GGCGCTCGGTCTGCCCGGTGACTGGAAACCGGTGGGGGAAGGAGTGTGCGAGCTGCGGATATTCGTGGGCATGGGCTATC
GCGTCTTTTTCGCGCACGATGGCAAAACAGTAGTGGTCCTGCTTTGCGGCGGCGATAAATCCACGCAAGACCGGGATATC
GAACTGGCCAAGTCGTATTGGCGGGAGTACAGGAAGCAGACATGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10362.15 Da        Isoelectric Point: 10.9102

>AT30997 WP_096360570.1 NZ_AP014879:c1433841-1433551 [Sulfuricaulis limicola]
MKSVPFKTSDHLKTRKDIVAYLNAALEDGEPAVLLEALRNVAQAKGGIAALAKTAGVSRESLYRTLSRRGNPKIDTVMAL
LRAMGLKLSIDQRKAA

Download         Length: 291 bp

>AT30997 NZ_AP014879:c1433841-1433551 [Sulfuricaulis limicola]
ATGAAAAGCGTCCCTTTCAAGACCTCGGATCATCTCAAGACACGCAAGGACATCGTGGCGTATCTCAATGCTGCGCTTGA
AGATGGCGAACCGGCGGTGCTGCTGGAGGCGCTCCGCAACGTGGCGCAGGCCAAAGGTGGAATCGCAGCACTGGCGAAGA
CGGCGGGCGTGAGCCGAGAGAGCCTCTACCGCACGCTTTCGCGCCGGGGTAATCCGAAGATCGACACCGTGATGGCTCTG
CTGCGGGCCATGGGGCTTAAACTGAGCATCGATCAGCGTAAGGCGGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References