Detailed information of TA system TA030992

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pasABC/RelE-HTH
• Location: 5478699..5479176
• Replicon: chromosome
• Accession: NZ_AP014862
• Organism: Pseudomonas furukawaii strain KF707

Toxin (Protein)

• Gene name: pasB
• Uniprot ID: -
• Locus tag: KF707C_RS25460
• Protein ID: WP_081608072.1
• Coordinates: 5478910..5479176 (+)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: L8MHY4
• Locus tag: KF707C_RS25455
• Protein ID: WP_004421422.1
• Coordinates: 5478699..5478926 (+)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KF707C_RS25430	5473987..5474184	-	198	WP_004421431.1	cation transporter	-
KF707C_RS25435	5474293..5474658	+	366	WP_004421429.1	hypothetical protein	-
KF707C_RS25440	5474723..5477164	+	2442	WP_004421427.1	heavy metal translocating P-type ATPase	-
KF707C_RS25445	5477161..5477562	+	402	WP_004421425.1	Cu(I)-responsive transcriptional regulator	-
KF707C_RS25450	5477528..5478430	-	903	WP_004421424.1	EamA family transporter	-
KF707C_RS25455	5478699..5478926	+	228	WP_004421422.1	ribbon-helix-helix protein, CopG family	Antitoxin
KF707C_RS25460	5478910..5479176	+	267	WP_081608072.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
KF707C_RS25465	5479386..5479850	-	465	WP_004421420.1	bacterioferritin	-
KF707C_RS25470	5479916..5480809	-	894	WP_004421417.1	serine protein kinase RIO	-
KF707C_RS25475	5481134..5481472	+	339	WP_003451119.1	hypothetical protein	-
KF707C_RS25480	5481581..5482858	-	1278	WP_003451118.1	acetyl-CoA C-acetyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-87)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10084.61 Da
• Isoelectric Point: 10.3398

>T30992 WP_081608072.1 NZ_AP014862:5478910-5479176 [Pseudomonas furukawaii]
MVWTIDYTDTARTQLRKLDKQTAKRILDFLDERVAGRADPRSTGKALTGPLGGLWRYRIGDVRVICDIQDGSLHILVVQL
GNRRDVYR

Nucleotide

• Length: 267 bp

>T30992 NZ_AP014862:5478910-5479176 [Pseudomonas furukawaii]
TTGGTCTGGACGATTGATTACACCGACACCGCCAGAACTCAGTTACGTAAGCTCGACAAGCAAACTGCCAAACGCATTCT
TGATTTCTTGGACGAGCGTGTCGCCGGCAGGGCTGACCCGCGCAGTACGGGAAAAGCTCTCACCGGCCCACTGGGTGGCT
TGTGGCGGTATCGAATAGGGGATGTTCGCGTGATATGCGACATTCAGGATGGCTCGCTACACATCCTGGTTGTCCAGCTA
GGCAACCGCCGAGACGTATACCGCTGA

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 8530.55 Da
• Isoelectric Point: 4.8182

>AT30992 WP_004421422.1 NZ_AP014862:5478699-5478926 [Pseudomonas furukawaii]
MATSIRLSPETERRLEFLAASTGRTKAYYLREIIDHGLTDMEDYYLAADVLERVRKGQESVHSAADVRKDLGLDD

Nucleotide

• Length: 228 bp

>AT30992 NZ_AP014862:5478699-5478926 [Pseudomonas furukawaii]
ATGGCTACTTCAATTCGACTTTCCCCTGAAACCGAACGGCGGTTGGAGTTCTTGGCGGCTAGCACCGGGCGTACCAAGGC
CTATTACCTCCGGGAAATCATCGACCACGGCCTAACCGATATGGAGGACTACTACCTCGCGGCTGACGTTCTTGAGCGGG
TACGCAAAGGTCAGGAATCAGTCCATTCGGCAGCGGACGTGAGGAAAGACCTTGGTCTGGACGATTGA

Structures

Antitoxin

• AlphaFold DB: L8MHY4