Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | phd-doc/HTH_IclR(antitoxin) |
Location | 1790016..1791711 | Replicon | chromosome |
Accession | NZ_AP014862 | ||
Organism | Pseudomonas furukawaii strain KF707 |
Toxin (Protein)
Gene name | doc | Uniprot ID | L8MJB4 |
Locus tag | KF707C_RS08390 | Protein ID | WP_003452766.1 |
Coordinates | 1790016..1790891 (+) | Length | 292 a.a. |
Antitoxin (Protein)
Gene name | phd | Uniprot ID | - |
Locus tag | KF707C_RS08395 | Protein ID | WP_003452765.1 |
Coordinates | 1790878..1791711 (+) | Length | 278 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KF707C_RS08365 | 1786024..1786875 | + | 852 | WP_081608092.1 | ABC transporter ATP-binding protein | - |
KF707C_RS08370 | 1786913..1787908 | + | 996 | WP_003452777.1 | ABC transporter substrate-binding protein | - |
KF707C_RS08375 | 1787918..1788694 | + | 777 | WP_003452773.1 | ABC transporter permease | - |
KF707C_RS08380 | 1788700..1789461 | + | 762 | WP_085986665.1 | SDR family oxidoreductase | - |
KF707C_RS08385 | 1789477..1790007 | + | 531 | WP_003452768.1 | cupin domain-containing protein | - |
KF707C_RS08390 | 1790016..1790891 | + | 876 | WP_003452766.1 | alpha/beta hydrolase | Toxin |
KF707C_RS08395 | 1790878..1791711 | + | 834 | WP_003452765.1 | IclR family transcriptional regulator | Antitoxin |
KF707C_RS08400 | 1791698..1792495 | + | 798 | WP_003452763.1 | SDR family oxidoreductase | - |
KF707C_RS08405 | 1792488..1794170 | + | 1683 | WP_003452760.1 | thiamine pyrophosphate-binding protein | - |
KF707C_RS08410 | 1794181..1794984 | + | 804 | WP_003452759.1 | aspartate dehydrogenase | - |
KF707C_RS08415 | 1794995..1796479 | + | 1485 | WP_003452757.1 | aldehyde dehydrogenase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 292 a.a. Molecular weight: 30818.33 Da Isoelectric Point: 7.8794
>T30984 WP_003452766.1 NZ_AP014862:1790016-1790891 [Pseudomonas furukawaii]
MNMAQTRIPTPRLQQCFPERLVTVADGARVAIRECGQGPVVVLLHGIGSGSASWLHCAQRLAEGNRVIAWDAPGYGLSTP
LPQARPKAVDYAARLEALLVALGVERCLLVGHSLGALMATAYAAGQGAQRVARLVLISPARGYGAEALRETGLRVRQQRL
DNLERLGIDGMASERTSRLLGRNPSEDALAWVRWNMARLNPAGYRQAVELLCGDDLLGNGRPAMPCEVHCGEDDAITSPE
ACGAIARGLDAPFSLIPAAGHASPIEQPDVVAGRIGHAQRLTLEGSAHGKA
MNMAQTRIPTPRLQQCFPERLVTVADGARVAIRECGQGPVVVLLHGIGSGSASWLHCAQRLAEGNRVIAWDAPGYGLSTP
LPQARPKAVDYAARLEALLVALGVERCLLVGHSLGALMATAYAAGQGAQRVARLVLISPARGYGAEALRETGLRVRQQRL
DNLERLGIDGMASERTSRLLGRNPSEDALAWVRWNMARLNPAGYRQAVELLCGDDLLGNGRPAMPCEVHCGEDDAITSPE
ACGAIARGLDAPFSLIPAAGHASPIEQPDVVAGRIGHAQRLTLEGSAHGKA
Download Length: 876 bp
>T30984 NZ_AP014862:1790016-1790891 [Pseudomonas furukawaii]
ATGAACATGGCGCAGACCCGCATCCCCACGCCGCGCTTGCAGCAGTGCTTCCCGGAGCGCCTGGTGACCGTCGCCGACGG
TGCCCGGGTGGCCATCCGCGAGTGCGGCCAGGGCCCGGTGGTGGTGCTCCTGCACGGTATCGGCTCCGGCTCGGCGTCCT
GGCTGCATTGCGCCCAGCGCCTGGCCGAGGGCAACCGCGTGATCGCCTGGGACGCCCCCGGCTACGGCCTGTCCACGCCG
CTGCCGCAGGCAAGACCGAAAGCGGTCGACTACGCCGCCCGGCTGGAGGCGCTGCTGGTGGCCCTGGGCGTCGAGCGTTG
CCTGCTGGTGGGGCACTCCCTGGGCGCGCTGATGGCCACCGCCTACGCCGCAGGCCAGGGCGCCCAGCGCGTCGCCCGCC
TGGTGCTGATCAGCCCGGCGCGAGGCTACGGCGCCGAGGCCCTGCGGGAAACCGGGCTGCGGGTGCGCCAGCAGCGCCTG
GACAACCTCGAGCGGCTGGGCATCGACGGCATGGCCAGCGAGCGCACCAGCCGGCTGCTGGGGCGCAACCCCAGCGAGGA
CGCCCTGGCCTGGGTGCGCTGGAACATGGCGCGGCTGAACCCGGCCGGCTACCGCCAGGCGGTGGAGCTGCTCTGCGGCG
ACGACCTGCTGGGCAACGGCCGGCCGGCGATGCCCTGCGAGGTGCATTGCGGCGAGGACGACGCCATCACCTCGCCGGAG
GCCTGCGGCGCCATCGCCCGGGGGCTGGACGCTCCCTTCTCGCTGATCCCCGCAGCCGGCCACGCCAGCCCCATCGAACA
ACCCGACGTGGTCGCAGGACGCATTGGTCACGCGCAACGCCTCACTCTTGAAGGATCCGCCCATGGAAAAGCCTGA
ATGAACATGGCGCAGACCCGCATCCCCACGCCGCGCTTGCAGCAGTGCTTCCCGGAGCGCCTGGTGACCGTCGCCGACGG
TGCCCGGGTGGCCATCCGCGAGTGCGGCCAGGGCCCGGTGGTGGTGCTCCTGCACGGTATCGGCTCCGGCTCGGCGTCCT
GGCTGCATTGCGCCCAGCGCCTGGCCGAGGGCAACCGCGTGATCGCCTGGGACGCCCCCGGCTACGGCCTGTCCACGCCG
CTGCCGCAGGCAAGACCGAAAGCGGTCGACTACGCCGCCCGGCTGGAGGCGCTGCTGGTGGCCCTGGGCGTCGAGCGTTG
CCTGCTGGTGGGGCACTCCCTGGGCGCGCTGATGGCCACCGCCTACGCCGCAGGCCAGGGCGCCCAGCGCGTCGCCCGCC
TGGTGCTGATCAGCCCGGCGCGAGGCTACGGCGCCGAGGCCCTGCGGGAAACCGGGCTGCGGGTGCGCCAGCAGCGCCTG
GACAACCTCGAGCGGCTGGGCATCGACGGCATGGCCAGCGAGCGCACCAGCCGGCTGCTGGGGCGCAACCCCAGCGAGGA
CGCCCTGGCCTGGGTGCGCTGGAACATGGCGCGGCTGAACCCGGCCGGCTACCGCCAGGCGGTGGAGCTGCTCTGCGGCG
ACGACCTGCTGGGCAACGGCCGGCCGGCGATGCCCTGCGAGGTGCATTGCGGCGAGGACGACGCCATCACCTCGCCGGAG
GCCTGCGGCGCCATCGCCCGGGGGCTGGACGCTCCCTTCTCGCTGATCCCCGCAGCCGGCCACGCCAGCCCCATCGAACA
ACCCGACGTGGTCGCAGGACGCATTGGTCACGCGCAACGCCTCACTCTTGAAGGATCCGCCCATGGAAAAGCCTGA
Antitoxin
Download Length: 278 a.a. Molecular weight: 30918.42 Da Isoelectric Point: 6.6960
>AT30984 WP_003452765.1 NZ_AP014862:1790878-1791711 [Pseudomonas furukawaii]
MEKPDDQQDKYIVPGLERGLLLLCEFSRKNRTLTAPELARRLKLPRSTIFRLLTTLETMGFVNRNGNEYRLGMAVLRLGF
EYLASLELTELGQPLLNQLCDEIRYPCNLVVRDGRSIVYVAKVSPSTLLTSTVNVGTRLPAHATVLGRILLQDLSLSELR
ELYPEEHLESFSPNTPKTVLELFDLVQSDRLRGFVQGEGFFESTISTVAAPVRDHSGRVVAAMGATIPSAHIDPSRIDGL
VSAVRHSADELSHLLNYTPDGHDKVTSIFRSKQHEPV
MEKPDDQQDKYIVPGLERGLLLLCEFSRKNRTLTAPELARRLKLPRSTIFRLLTTLETMGFVNRNGNEYRLGMAVLRLGF
EYLASLELTELGQPLLNQLCDEIRYPCNLVVRDGRSIVYVAKVSPSTLLTSTVNVGTRLPAHATVLGRILLQDLSLSELR
ELYPEEHLESFSPNTPKTVLELFDLVQSDRLRGFVQGEGFFESTISTVAAPVRDHSGRVVAAMGATIPSAHIDPSRIDGL
VSAVRHSADELSHLLNYTPDGHDKVTSIFRSKQHEPV
Download Length: 834 bp
>AT30984 NZ_AP014862:1790878-1791711 [Pseudomonas furukawaii]
ATGGAAAAGCCTGACGATCAACAAGACAAGTACATAGTGCCCGGCCTGGAGCGCGGCCTGCTGCTGCTCTGCGAGTTCAG
CCGGAAGAACCGCACCCTGACCGCCCCCGAGCTGGCCCGGCGCCTGAAGCTGCCGCGCTCGACGATCTTCCGGCTGCTGA
CGACGCTGGAAACCATGGGCTTCGTCAATCGCAACGGCAACGAGTACCGCCTGGGCATGGCCGTGCTGCGCCTGGGCTTC
GAGTACCTGGCCTCGCTGGAACTCACCGAACTGGGCCAGCCGCTGCTGAACCAGCTCTGCGACGAGATCCGCTACCCCTG
CAACCTGGTGGTCCGCGATGGCCGTTCCATCGTCTACGTGGCCAAGGTCTCGCCCTCGACCCTGCTCACCAGCACGGTCA
ACGTCGGCACCCGCCTGCCGGCCCACGCCACGGTGCTCGGCCGCATCCTGCTGCAGGACCTGTCCCTCTCCGAGCTGCGC
GAGCTGTACCCGGAAGAGCACCTGGAAAGCTTCTCGCCGAACACCCCGAAGACCGTGCTGGAGCTGTTCGACCTGGTGCA
GAGCGACCGCCTGCGCGGATTCGTCCAGGGCGAGGGCTTCTTCGAGTCGACCATCTCCACGGTCGCCGCGCCGGTGCGCG
ACCACAGCGGCCGGGTGGTGGCCGCCATGGGCGCCACCATTCCCTCGGCGCACATCGATCCGTCCCGCATCGATGGCCTG
GTGAGCGCCGTGCGCCACAGCGCCGATGAGCTGTCCCACCTGCTGAACTACACCCCGGACGGCCACGACAAGGTGACCTC
CATCTTCCGGAGCAAGCAGCATGAGCCTGTGTGA
ATGGAAAAGCCTGACGATCAACAAGACAAGTACATAGTGCCCGGCCTGGAGCGCGGCCTGCTGCTGCTCTGCGAGTTCAG
CCGGAAGAACCGCACCCTGACCGCCCCCGAGCTGGCCCGGCGCCTGAAGCTGCCGCGCTCGACGATCTTCCGGCTGCTGA
CGACGCTGGAAACCATGGGCTTCGTCAATCGCAACGGCAACGAGTACCGCCTGGGCATGGCCGTGCTGCGCCTGGGCTTC
GAGTACCTGGCCTCGCTGGAACTCACCGAACTGGGCCAGCCGCTGCTGAACCAGCTCTGCGACGAGATCCGCTACCCCTG
CAACCTGGTGGTCCGCGATGGCCGTTCCATCGTCTACGTGGCCAAGGTCTCGCCCTCGACCCTGCTCACCAGCACGGTCA
ACGTCGGCACCCGCCTGCCGGCCCACGCCACGGTGCTCGGCCGCATCCTGCTGCAGGACCTGTCCCTCTCCGAGCTGCGC
GAGCTGTACCCGGAAGAGCACCTGGAAAGCTTCTCGCCGAACACCCCGAAGACCGTGCTGGAGCTGTTCGACCTGGTGCA
GAGCGACCGCCTGCGCGGATTCGTCCAGGGCGAGGGCTTCTTCGAGTCGACCATCTCCACGGTCGCCGCGCCGGTGCGCG
ACCACAGCGGCCGGGTGGTGGCCGCCATGGGCGCCACCATTCCCTCGGCGCACATCGATCCGTCCCGCATCGATGGCCTG
GTGAGCGCCGTGCGCCACAGCGCCGATGAGCTGTCCCACCTGCTGAACTACACCCCGGACGGCCACGACAAGGTGACCTC
CATCTTCCGGAGCAAGCAGCATGAGCCTGTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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