Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 1322647..1324064 Replicon chromosome
Accession NZ_AP014862
Organism Pseudomonas furukawaii strain KF707

Toxin (Protein)


Gene name - Uniprot ID L8MIQ2
Locus tag KF707C_RS06145 Protein ID WP_003451691.1
Coordinates 1322647..1323216 (+) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID L8MFK6
Locus tag KF707C_RS06150 Protein ID WP_003451694.1
Coordinates 1323222..1324064 (+) Length 281 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KF707C_RS06140 1318916..1322395 - 3480 WP_003451688.1 hybrid sensor histidine kinase/response regulator -
KF707C_RS06145 1322647..1323216 + 570 WP_003451691.1 GNAT family N-acetyltransferase Toxin
KF707C_RS06150 1323222..1324064 + 843 WP_003451694.1 AraC family transcriptional regulator Antitoxin
KF707C_RS06155 1324101..1324832 + 732 WP_003451697.1 AzlC family ABC transporter permease -
KF707C_RS06160 1324814..1325143 + 330 WP_003451701.1 AzlD domain-containing protein -
KF707C_RS06165 1325241..1327115 + 1875 WP_003451704.1 MFS transporter -
KF707C_RS06170 1327167..1327481 - 315 WP_003451706.1 quaternary ammonium compound efflux SMR transporter SugE -
KF707C_RS06175 1327631..1328572 - 942 WP_003451708.1 bile acid:sodium symporter family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-145)

Antitoxin

DNA binding HTH domain, AraC-type

(194-271)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21077.14 Da        Isoelectric Point: 7.3196

>T30983 WP_003451691.1 NZ_AP014862:1322647-1323216 [Pseudomonas furukawaii]
MFNPQPVALQRGALRLDPLAEADIPALVTLAEANREALVYMSGPLRPDWYRQGLAAQREGDALVFAIRLGDNLVGTTRFA
DFMPSLPAAEIGWTWLAGSEHGSGLNASIKYLMLRHAFEDWQLVRVQLKTAASNLRAQRAIEKLGALREGVLRNHRRLAD
GRLDDSVLYSITDKDWPEVKQRLEALFSA

Download         Length: 570 bp

>T30983 NZ_AP014862:1322647-1323216 [Pseudomonas furukawaii]
ATGTTCAATCCACAACCGGTCGCACTGCAGCGAGGCGCCTTGCGCCTGGACCCGCTGGCAGAGGCCGACATCCCGGCCCT
GGTGACCCTGGCCGAAGCCAACCGCGAGGCCCTGGTCTACATGAGCGGCCCCTTGCGTCCCGACTGGTATCGCCAGGGCC
TGGCCGCCCAGCGGGAGGGCGACGCCCTGGTCTTCGCCATTCGCCTGGGCGACAACCTGGTGGGCACCACGCGCTTCGCC
GACTTCATGCCCAGCCTGCCGGCCGCCGAGATCGGCTGGACCTGGCTGGCCGGCAGCGAACACGGCAGTGGCCTCAACGC
CTCGATCAAGTACCTGATGTTGCGCCATGCCTTCGAGGACTGGCAGCTGGTGCGGGTGCAACTGAAGACGGCCGCCAGCA
ACCTGCGTGCCCAGCGCGCCATCGAGAAACTCGGTGCCCTGCGCGAAGGCGTGTTGCGCAACCATCGACGGCTGGCCGAC
GGCCGCCTGGATGACAGCGTGTTGTACAGCATCACCGACAAGGACTGGCCGGAGGTGAAGCAACGCCTGGAGGCGCTGTT
CAGCGCCTGA

Antitoxin


Download         Length: 281 a.a.        Molecular weight: 31159.35 Da        Isoelectric Point: 7.6335

>AT30983 WP_003451694.1 NZ_AP014862:1323222-1324064 [Pseudomonas furukawaii]
MGEPRENVHFWQAGHLGGLELLSARYIDHRFAPHAHDGYAIAVIESGAERYRYRGVEHLAPAGSLALINPDEVHTGSKGD
DDGWRYRVFYPEAEQVRAVLDELELPIAGLPALRGSVHRDADLVDGFLCLHRLLESPSSALEQQTAWRDALLALFRRHAR
LPDPAMPGREPLAVLRAKDLLRERLAEPPSLEALAAEVNLSPFHFARTFRRATGLPPHAWLKQQRLDQARALLKAGCAPV
NVAAQLGFADQSHLTRQFKQAYGVGPGEYRNACARSFKTH

Download         Length: 843 bp

>AT30983 NZ_AP014862:1323222-1324064 [Pseudomonas furukawaii]
ATGGGCGAGCCGCGGGAGAACGTGCATTTCTGGCAGGCCGGCCATCTGGGTGGGCTGGAACTGCTGTCCGCGCGCTACAT
CGATCACCGCTTCGCGCCCCACGCTCACGATGGCTACGCGATCGCTGTGATCGAGAGTGGGGCGGAGCGCTATCGCTACC
GGGGTGTCGAGCACCTGGCGCCCGCCGGCAGCCTGGCGCTGATCAACCCGGATGAGGTGCATACCGGCTCCAAGGGTGAT
GACGACGGCTGGCGCTACCGGGTGTTCTATCCCGAAGCGGAGCAGGTCCGTGCCGTGCTCGACGAGCTGGAGCTGCCGAT
TGCCGGTCTGCCGGCGCTGCGGGGCAGCGTGCACCGCGACGCCGACCTGGTGGACGGTTTCCTGTGCCTGCATCGCCTGC
TGGAATCCCCGTCCAGCGCGCTGGAGCAGCAGACCGCCTGGCGCGATGCCTTGCTGGCGCTGTTCCGCCGTCACGCCCGG
CTGCCTGATCCGGCCATGCCCGGACGGGAGCCCCTGGCCGTGCTGCGGGCCAAGGATCTGTTGCGGGAGCGCCTGGCGGA
GCCGCCTTCCCTGGAGGCGCTGGCGGCCGAGGTGAACCTGTCGCCGTTTCATTTCGCCCGTACCTTCCGCCGTGCCACGG
GCCTGCCACCCCATGCCTGGCTCAAGCAGCAGCGCCTGGACCAGGCCCGGGCCCTGCTCAAGGCCGGGTGCGCGCCGGTG
AACGTGGCGGCGCAGTTGGGTTTCGCAGACCAGAGCCACCTGACCCGCCAGTTCAAGCAGGCCTATGGCGTCGGGCCGGG
CGAATACCGCAACGCCTGCGCAAGATCGTTCAAGACCCACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB L8MIQ2

Antitoxin

Source ID Structure
AlphaFold DB L8MFK6

References