Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 3673205..3673733 Replicon chromosome
Accession NZ_AP014854
Organism Blastochloris viridis strain DSM 133

Toxin (Protein)


Gene name stbE Uniprot ID A0A0H5BJ02
Locus tag BV133_RS16010 Protein ID WP_055036861.1
Coordinates 3673205..3673495 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0H5BFZ2
Locus tag BV133_RS16015 Protein ID WP_055036860.1
Coordinates 3673485..3673733 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BV133_RS15985 3668330..3669856 + 1527 WP_055036866.1 phage portal protein -
BV133_RS15990 3669874..3671832 + 1959 WP_055036865.1 HK97 family phage prohead protease -
BV133_RS15995 3671917..3672255 + 339 WP_055036864.1 DUF2190 family protein -
BV133_RS16000 3672252..3672566 + 315 WP_055036863.1 hypothetical protein -
BV133_RS16005 3672568..3673197 + 630 WP_055036862.1 hypothetical protein -
BV133_RS16010 3673205..3673495 - 291 WP_055036861.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BV133_RS16015 3673485..3673733 - 249 WP_055036860.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BV133_RS16020 3673818..3674252 + 435 WP_055036859.1 hypothetical protein -
BV133_RS17190 3674269..3674544 + 276 Protein_3218 hypothetical protein -
BV133_RS16030 3675795..3676235 + 441 WP_055036856.1 hypothetical protein -
BV133_RS16035 3676232..3676456 + 225 WP_055036855.1 hypothetical protein -
BV133_RS16040 3676461..3678713 + 2253 WP_055036854.1 phage tail length tape measure family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3630480..3695441 64961


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11310.14 Da        Isoelectric Point: 10.3633

>T30908 WP_055036861.1 NZ_AP014854:c3673495-3673205 [Blastochloris viridis]
MSYELAFLDEALKEWRKLDSTMRDQFKAKLAERLENPNIPSARLHGAKERYKIKLRSAGYRLVYEVRDLELLVLVVAVGK
RERNEIYKTAARRKAD

Download         Length: 291 bp

>T30908 NZ_AP014854:c3673495-3673205 [Blastochloris viridis]
ATGAGCTATGAGCTCGCCTTCCTCGACGAGGCGTTGAAGGAATGGCGCAAGCTCGACAGCACCATGCGAGACCAGTTCAA
GGCCAAGCTCGCCGAGAGATTGGAAAACCCGAATATTCCCTCCGCGCGTCTCCATGGCGCAAAGGAACGCTACAAGATTA
AGCTGCGCAGCGCCGGTTATCGGCTGGTCTATGAGGTTCGGGACCTGGAGCTGCTGGTTCTCGTTGTCGCCGTCGGCAAG
CGGGAACGCAACGAAATCTACAAGACGGCAGCCCGGCGGAAAGCGGATTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8860.09 Da        Isoelectric Point: 4.5778

>AT30908 WP_055036860.1 NZ_AP014854:c3673733-3673485 [Blastochloris viridis]
MAHAVHATTVASISDLKKNPMGTVAAGEGFPVAILNRNEPAFYCIPAKAYEELLERLEDLELNAIADAREGQAIHKVSLD
EL

Download         Length: 249 bp

>AT30908 NZ_AP014854:c3673733-3673485 [Blastochloris viridis]
ATGGCGCATGCCGTTCACGCCACTACGGTCGCCAGCATTTCGGACCTGAAGAAAAATCCCATGGGCACGGTCGCTGCCGG
CGAAGGCTTCCCCGTCGCGATCCTCAACCGCAACGAACCGGCCTTCTATTGCATCCCGGCCAAGGCTTACGAGGAACTGC
TGGAGCGGCTCGAAGACCTTGAGTTGAACGCCATCGCGGACGCTCGCGAGGGTCAGGCGATCCACAAGGTTTCGCTCGAT
GAGCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H5BJ02

Antitoxin

Source ID Structure
AlphaFold DB A0A0H5BFZ2

References