Detailed information of TA system TA030907

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): hicAB/HicA-HicB
• Location: 97768..98243
• Replicon: chromosome
• Accession: NZ_AP014854
• Organism: Blastochloris viridis strain DSM 133

Toxin (Protein)

• Gene name: hicA
• Uniprot ID: -
• Locus tag: BV133_RS00405
• Protein ID: WP_055038701.1
• Coordinates: 98052..98243 (-)
• Length: 64 a.a.

Antitoxin (Protein)

• Gene name: hicB
• Uniprot ID: A0A0P0ID03
• Locus tag: BV133_RS00400
• Protein ID: WP_055036760.1
• Coordinates: 97768..98055 (-)
• Length: 96 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BV133_RS16545	95723..96235	+	513	WP_145911849.1	hypothetical protein	-
BV133_RS00395	96547..96795	+	249	WP_055036761.1	DUF2442 domain-containing protein	-
BV133_RS16550	96854..97297	+	444	WP_145911850.1	hypothetical protein	-
BV133_RS00400	97768..98055	-	288	WP_055036760.1	type II toxin-antitoxin system HicB family antitoxin	Antitoxin
BV133_RS00405	98052..98243	-	192	WP_055038701.1	type II toxin-antitoxin system HicA family toxin	Toxin
BV133_RS00410	98348..98695	-	348	WP_055036759.1	ArsC family reductase	-
BV133_RS00415	98940..99269	+	330	WP_058124826.1	hypothetical protein	-
BV133_RS00420	99322..99762	-	441	WP_055036757.1	isoprenylcysteine carboxylmethyltransferase family protein	-
BV133_RS00425	99922..100212	+	291	WP_055036756.1	hypothetical protein	-
BV133_RS00430	100278..100493	-	216	WP_055036755.1	hypothetical protein	-
BV133_RS00435	101147..102202	+	1056	WP_082417334.1	polysaccharide deacetylase family protein	-
BV133_RS00440	102436..102738	+	303	WP_055038700.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• HicA mRNA interferase family (3-59)

Antitoxin

• HicB-like antitoxin of toxin-antitoxin system (5-86)

Sequences

Toxin

Protein

• Length: 64 a.a.
• Molecular weight: 7255.39 Da
• Isoelectric Point: 10.9847

>T30907 WP_055038701.1 NZ_AP014854:c98243-98052 [Blastochloris viridis]
IDSRDIIRLLEQDGWIYVGATGSHYHFRHPAKPGKVTVPHPRKDLHPKTARSIFRMAGLKEPR

Nucleotide

• Length: 192 bp

>T30907 NZ_AP014854:c98243-98052 [Blastochloris viridis]
ATCGATTCACGCGATATCATCCGCCTGTTGGAGCAGGACGGGTGGATTTATGTGGGCGCCACCGGCAGCCACTACCACTT
CAGGCATCCGGCAAAGCCCGGCAAGGTCACCGTGCCTCACCCGCGCAAGGACTTGCATCCGAAGACCGCGCGATCGATCT
TTCGGATGGCGGGCTTGAAGGAGCCGCGATGA

Antitoxin

Protein

• Length: 96 a.a.
• Molecular weight: 9564.56 Da
• Isoelectric Point: 3.9005

>AT30907 WP_055036760.1 NZ_AP014854:c98055-97768 [Blastochloris viridis]
MMAGYLALVHKDAGTSYGVSFPDVPGCVSAGDTLEEALANAAEALGGHLALLATDGDSVPSPRSFEALRADASLADEFED
AVVSFVQPHATASAA

Nucleotide

• Length: 288 bp

>AT30907 NZ_AP014854:c98055-97768 [Blastochloris viridis]
ATGATGGCCGGTTATCTCGCATTGGTGCACAAGGACGCGGGCACGAGCTACGGCGTCAGCTTTCCGGACGTTCCGGGCTG
CGTGTCGGCTGGCGATACGCTGGAGGAAGCGCTGGCCAATGCGGCGGAGGCGCTTGGCGGACACCTCGCTTTGCTCGCCA
CCGATGGCGACTCGGTGCCGTCCCCGCGCAGCTTCGAAGCCTTGCGGGCGGATGCCAGCCTCGCCGACGAGTTTGAGGAT
GCGGTGGTGAGCTTCGTTCAGCCGCACGCCACCGCCTCGGCGGCCTGA

Structures

Antitoxin

• AlphaFold DB: A0A0P0ID03