Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-CC2985
Location 13489..14041 Replicon plasmid pMPPM05
Accession NZ_AP014814
Organism Methylorubrum populi strain P-1M

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag MPPM_RS27600 Protein ID WP_096488141.1
Coordinates 13489..13779 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag MPPM_RS27605 Protein ID WP_096488142.1
Coordinates 13772..14041 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPPM_RS27580 9191..9772 + 582 WP_096488138.1 hypothetical protein -
MPPM_RS27585 9828..11531 - 1704 WP_096488139.1 type IV secretory system conjugative DNA transfer family protein -
MPPM_RS27590 11778..12116 + 339 WP_197705086.1 hypothetical protein -
MPPM_RS27595 12204..12947 - 744 WP_096488140.1 GntR family transcriptional regulator -
MPPM_RS27600 13489..13779 - 291 WP_096488141.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MPPM_RS27605 13772..14041 - 270 WP_096488142.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
MPPM_RS27610 14301..14987 + 687 WP_096488143.1 ParA family protein -
MPPM_RS27615 14987..15352 + 366 WP_096488144.1 stability/partitioning determinant -
MPPM_RS27620 16089..16670 - 582 WP_096488145.1 recombinase family protein -
MPPM_RS27625 16938..17867 - 930 WP_096488146.1 IS110 family transposase -
MPPM_RS27630 18162..18404 - 243 WP_096488147.1 hypothetical protein -
MPPM_RS27635 18453..18650 - 198 Protein_20 DUF411 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..29506 29506


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin

Antitoxin ParD

(6-67)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10604.15 Da        Isoelectric Point: 6.0642

>T30888 WP_096488141.1 NZ_AP014814:c13779-13489 [Methylorubrum populi]
VGSYQLTGRADADILDVFLYGLTEFGMFQAERYQGILEHAFQLLADNPRMGRAAEMIGARVRRHECGAHVILYEEAADGV
LILAVVHGSSVRRLSL

Download         Length: 291 bp

>T30888 NZ_AP014814:c13779-13489 [Methylorubrum populi]
GTGGGTAGCTACCAGCTCACTGGCCGCGCCGACGCCGACATCCTCGACGTGTTCCTCTACGGCCTCACCGAATTTGGGAT
GTTCCAGGCCGAACGCTATCAGGGCATTCTGGAGCACGCCTTTCAGCTCTTGGCCGACAATCCTCGTATGGGCCGGGCTG
CAGAGATGATCGGAGCAAGGGTTCGGCGCCACGAATGCGGCGCACACGTCATCCTCTACGAGGAGGCAGCGGACGGCGTC
CTGATCCTCGCGGTCGTCCACGGCAGCAGCGTCCGGCGGCTTTCACTGTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10118.39 Da        Isoelectric Point: 8.6002

>AT30888 WP_096488142.1 NZ_AP014814:c14041-13772 [Methylorubrum populi]
MATMTISLPDPMKEWIEAQIQQGDYASTSDYVRDLVRRDRERRAHPELTIDDLRRIVDESRASGISRRSVPDIMSEAKKV
ASARGTTRG

Download         Length: 270 bp

>AT30888 NZ_AP014814:c14041-13772 [Methylorubrum populi]
ATGGCGACGATGACAATTTCCCTGCCCGATCCCATGAAGGAATGGATCGAAGCTCAGATCCAGCAGGGCGACTACGCCAG
CACGAGCGACTATGTGCGCGACCTCGTGCGCCGCGACCGCGAGCGCCGGGCCCACCCCGAACTGACGATTGACGATCTCC
GCCGCATCGTGGACGAATCCCGCGCCAGCGGCATCAGCCGCCGCAGCGTCCCTGACATCATGTCCGAGGCCAAGAAGGTT
GCGAGCGCTCGCGGCACGACGCGTGGGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References