Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH_31
Location 4884981..4885630 Replicon chromosome
Accession NZ_AP014809
Organism Methylorubrum populi strain P-1M

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MPPM_RS22580 Protein ID WP_096486972.1
Coordinates 4885376..4885630 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MPPM_RS22575 Protein ID WP_096486971.1
Coordinates 4884981..4885355 (-) Length 125 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPPM_RS22555 4880631..4881161 - 531 WP_096486967.1 GNAT family N-acetyltransferase -
MPPM_RS22560 4881336..4881773 + 438 WP_096486968.1 DUF983 domain-containing protein -
MPPM_RS22565 4881965..4883704 - 1740 WP_096486969.1 L-lactate permease -
MPPM_RS22570 4884007..4884930 + 924 WP_096486970.1 manganese catalase family protein -
MPPM_RS22575 4884981..4885355 - 375 WP_096486971.1 helix-turn-helix domain-containing protein Antitoxin
MPPM_RS22580 4885376..4885630 - 255 WP_096486972.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MPPM_RS22585 4885719..4886615 - 897 WP_096486973.1 squalene/phytoene synthase family protein -
MPPM_RS22590 4886645..4887043 - 399 WP_096486974.1 hypothetical protein -
MPPM_RS22595 4887162..4888106 - 945 WP_096487984.1 protein translocase subunit SecF -
MPPM_RS22600 4888212..4889810 - 1599 WP_096486975.1 protein translocase subunit SecD -
MPPM_RS22605 4889878..4890210 - 333 WP_017483888.1 preprotein translocase subunit YajC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin

Cro/C1-type helix-turn-helix domain

(66-122)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9305.94 Da        Isoelectric Point: 10.5231

>T30887 WP_096486972.1 NZ_AP014809:c4885630-4885376 [Methylorubrum populi]
MAAVLYSKAALKALLRLPPDVTRKIRLKFEQYAAAPESLANNVKALRGEQGVLRLRVGDWRVLFTEDGIVVAVIRIAPRG
DAYD

Download         Length: 255 bp

>T30887 NZ_AP014809:c4885630-4885376 [Methylorubrum populi]
ATGGCCGCGGTCCTCTACAGCAAAGCTGCCTTGAAGGCCCTGCTTCGGCTCCCGCCCGACGTCACTCGAAAGATTCGCCT
TAAATTCGAGCAGTATGCGGCCGCACCCGAGTCACTCGCCAACAACGTGAAAGCGCTTCGAGGCGAGCAAGGTGTCCTGC
GTCTGCGCGTCGGGGATTGGCGCGTGCTCTTCACAGAGGACGGTATCGTGGTTGCGGTCATCAGGATCGCACCACGGGGT
GACGCTTATGACTGA

Antitoxin


Download         Length: 125 a.a.        Molecular weight: 13201.97 Da        Isoelectric Point: 4.6265

>AT30887 WP_096486971.1 NZ_AP014809:c4885355-4884981 [Methylorubrum populi]
MTRQIITTPGGERLVLMPEADFEALVAAAEDNADRTAVAEFRRKLAAGDEELLPAALVERLISGENRVRIWREHRGLSGA
ALAKQAGLAQAYLSQIETGAREGTVETYGKLAAALGVSLDDLVG

Download         Length: 375 bp

>AT30887 NZ_AP014809:c4885355-4884981 [Methylorubrum populi]
ATGACCAGGCAGATCATCACGACGCCCGGCGGCGAACGACTTGTGCTGATGCCCGAGGCGGATTTCGAGGCGCTGGTCGC
AGCCGCTGAAGACAATGCGGACCGGACCGCCGTCGCGGAGTTTCGGCGCAAGCTCGCTGCCGGCGATGAAGAGCTGCTTC
CGGCTGCTCTCGTCGAGCGTCTCATTTCCGGTGAGAACCGTGTCCGCATCTGGCGCGAGCACCGCGGCCTGAGCGGGGCC
GCACTCGCCAAACAGGCCGGTCTGGCACAGGCGTACCTGTCACAGATCGAGACGGGAGCACGGGAGGGTACCGTCGAAAC
CTACGGCAAGCTCGCCGCGGCTCTCGGGGTTTCCCTGGATGATCTCGTGGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References