Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1676675..1677210 Replicon chromosome
Accession NZ_AP014809
Organism Methylorubrum populi strain P-1M

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag MPPM_RS07700 Protein ID WP_096484549.1
Coordinates 1676920..1677210 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag MPPM_RS07695 Protein ID WP_162296259.1
Coordinates 1676675..1676923 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPPM_RS07680 1671888..1673471 - 1584 WP_096484545.1 hypothetical protein -
MPPM_RS07685 1673471..1674859 - 1389 WP_096484546.1 SWIM zinc finger family protein -
MPPM_RS07690 1675055..1676542 - 1488 WP_096484547.1 glucose-6-phosphate dehydrogenase -
MPPM_RS07695 1676675..1676923 + 249 WP_162296259.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
MPPM_RS07700 1676920..1677210 + 291 WP_096484549.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MPPM_RS07705 1677303..1677941 + 639 WP_096484550.1 uracil-DNA glycosylase family protein -
MPPM_RS07710 1678201..1678899 + 699 WP_096484551.1 orotidine-5'-phosphate decarboxylase -
MPPM_RS07715 1678901..1679245 + 345 WP_096484552.1 DUF1330 domain-containing protein -
MPPM_RS07720 1679271..1679897 - 627 WP_096484553.1 TetR/AcrR family transcriptional regulator -
MPPM_RS07725 1680136..1680918 + 783 WP_096484554.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Antitoxin ParD

(4-72)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11181.60 Da        Isoelectric Point: 10.2198

>T30885 WP_096484549.1 NZ_AP014809:1676920-1677210 [Methylorubrum populi]
MSVRLSPRARADLSRIWDDSAERWGADQADRYTRLLAEGFDRLAEDPARGRRADEIRSGYFRFSVGSHVLFYRLSTDGGI
EIIRILHGRMDFKRHL

Download         Length: 291 bp

>T30885 NZ_AP014809:1676920-1677210 [Methylorubrum populi]
ATGAGCGTCCGCCTCTCGCCGAGGGCGCGGGCGGATCTCAGCCGGATATGGGACGATTCGGCCGAGCGCTGGGGGGCGGA
TCAGGCCGACCGCTATACCCGCCTTCTGGCCGAGGGTTTCGATCGACTGGCCGAGGATCCGGCTCGGGGTCGGAGGGCGG
ACGAGATCCGCAGCGGGTATTTCCGCTTCTCCGTGGGCTCGCACGTCCTGTTCTACCGCCTGAGCACCGACGGCGGCATC
GAGATCATCCGCATCCTTCACGGGCGGATGGATTTCAAACGCCATCTTTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9119.03 Da        Isoelectric Point: 4.7105

>AT30885 WP_162296259.1 NZ_AP014809:1676675-1676923 [Methylorubrum populi]
MSRNTSVSLGEHFAQFIDRQVERGRYGSASEVVRAGLRLLEEQEAALDTLRAALIEGEESGSPEPFDTEAFLREKREGAH
RG

Download         Length: 249 bp

>AT30885 NZ_AP014809:1676675-1676923 [Methylorubrum populi]
ATGTCGCGCAACACGTCCGTCTCACTCGGCGAGCACTTTGCACAGTTCATCGACCGTCAGGTCGAGAGGGGACGTTACGG
CTCCGCCAGCGAAGTGGTCCGGGCCGGGCTTCGTCTCCTGGAGGAGCAGGAGGCCGCCCTCGACACGCTCCGGGCCGCAC
TGATCGAGGGGGAGGAGAGCGGCTCGCCCGAGCCGTTCGACACGGAGGCCTTCCTCCGGGAGAAGCGTGAGGGCGCGCAC
CGCGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References