Detailed information of TA system TA030881

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): virT-relB/YafQ-RelB
• Location: 1923054..1923574
• Replicon: chromosome
• Accession: NZ_AP014724
• Organism: Sulfurospirillum cavolei strain UCH003

Toxin (Protein)

• Gene name: virT
• Uniprot ID: -
• Locus tag: UCH003_RS09670
• Protein ID: WP_060826360.1
• Coordinates: 1923054..1923326 (-)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: UCH003_RS09675
• Protein ID: WP_060826361.1
• Coordinates: 1923323..1923574 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
UCH003_RS09650	1919894..1920337	+	444	WP_060826356.1	NUDIX domain-containing protein	-
UCH003_RS09655	1920413..1921777	-	1365	WP_060826357.1	OprD family outer membrane porin	-
UCH003_RS09660	1921911..1922372	-	462	WP_144441007.1	hypothetical protein	-
UCH003_RS09665	1922635..1922961	+	327	WP_060826359.1	hypothetical protein	-
UCH003_RS09670	1923054..1923326	-	273	WP_060826360.1	type II toxin-antitoxin system YafQ family toxin	Toxin
UCH003_RS09675	1923323..1923574	-	252	WP_060826361.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
UCH003_RS09680	1923629..1924762	-	1134	WP_060826362.1	hypothetical protein	-
UCH003_RS09685	1924907..1925767	+	861	WP_060826363.1	EamA family transporter	-
UCH003_RS09690	1926251..1926904	+	654	WP_060826364.1	4Fe-4S dicluster domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (5-89)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (6-69)

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10465.30 Da
• Isoelectric Point: 9.3596

>T30881 WP_060826360.1 NZ_AP014724:c1923326-1923054 [Sulfurospirillum cavolei]
MKYAIFRTSSFKKAYKKLSSSEQELVLTIVLKLAQGESLDEKYKDHFLIGNYKGCRECHIKPDLLLIYKINNDEVELVLV
EVGKHSKLFK

Nucleotide

• Length: 273 bp

>T30881 NZ_AP014724:c1923326-1923054 [Sulfurospirillum cavolei]
ATGAAATACGCCATCTTTCGTACATCTTCTTTCAAAAAAGCCTATAAAAAGCTCTCATCCTCTGAGCAAGAACTTGTTTT
AACGATTGTTCTTAAACTTGCTCAGGGTGAAAGTTTGGATGAAAAATACAAAGATCATTTTCTGATAGGCAACTATAAAG
GATGCAGGGAGTGTCACATTAAACCTGATTTACTGCTCATCTACAAAATCAATAACGATGAAGTGGAATTAGTTTTGGTG
GAAGTTGGTAAGCATTCTAAATTGTTTAAATAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9443.97 Da
• Isoelectric Point: 6.3501

>AT30881 WP_060826361.1 NZ_AP014724:c1923574-1923323 [Sulfurospirillum cavolei]
MRTGTSVRIDEETKIIASEVLKQYGMNLSEGINLFCKQVAMTYSIPFELKVPTERMKKALKELEKREGKSFDSIEALKAD
LES

Nucleotide

• Length: 252 bp

>AT30881 NZ_AP014724:c1923574-1923323 [Sulfurospirillum cavolei]
ATGAGAACAGGAACCAGTGTTCGTATTGATGAAGAGACTAAGATTATTGCTTCAGAAGTGTTAAAACAGTATGGTATGAA
CCTCAGTGAAGGCATTAACCTTTTTTGTAAGCAAGTTGCTATGACGTATTCCATCCCTTTTGAGTTAAAAGTGCCAACGG
AGAGAATGAAAAAAGCACTGAAAGAACTAGAAAAAAGAGAAGGAAAATCCTTTGATTCCATCGAAGCACTCAAAGCCGAT
CTTGAGTCATGA