Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 792948..793544 Replicon chromosome
Accession NZ_AP014703
Organism Pseudomonas sp. St290

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PBDP_RS03385 Protein ID WP_109752224.1
Coordinates 793242..793544 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PBDP_RS03380 Protein ID WP_109752223.1
Coordinates 792948..793238 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PBDP_RS03360 (PBDP_0665) 789191..791317 - 2127 WP_212801811.1 TonB-dependent copper receptor -
PBDP_RS03365 (PBDP_0666) 791402..791806 - 405 WP_163858909.1 DUF2946 domain-containing protein -
PBDP_RS03370 (PBDP_0667) 791864..792343 - 480 WP_109752221.1 copper chaperone PCu(A)C -
PBDP_RS03375 (PBDP_0668) 792391..792789 - 399 WP_116834073.1 DUF2946 domain-containing protein -
PBDP_RS03380 (PBDP_0669) 792948..793238 - 291 WP_109752223.1 putative addiction module antidote protein Antitoxin
PBDP_RS03385 (PBDP_0670) 793242..793544 - 303 WP_109752224.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PBDP_RS03390 (PBDP_0671) 793737..794465 - 729 WP_109752225.1 cobalt-precorrin-6A reductase -
PBDP_RS03395 (PBDP_0672) 794462..795559 - 1098 WP_212801812.1 cobalt-precorrin-5B (C(1))-methyltransferase -
PBDP_RS03400 (PBDP_0673) 795552..796763 - 1212 WP_212801813.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(5-94)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11268.84 Da        Isoelectric Point: 9.5454

>T30872 WP_109752224.1 NZ_AP014703:c793544-793242 [Pseudomonas sp. St290]
MIEFEHSRVFSSWLSGLKDISGKARIIARLRSAEHGNFGDCEPVGSAVYEMRIHSGPGYRVYFSRRGPVFYLLLVGGDKS
TQKRDITRAIQMAQTMGNEE

Download         Length: 303 bp

>T30872 NZ_AP014703:c793544-793242 [Pseudomonas sp. St290]
ATGATCGAATTTGAACACTCCCGAGTATTTTCAAGCTGGCTTAGCGGGTTGAAGGACATCTCTGGGAAGGCTCGCATCAT
CGCCAGGCTTCGATCTGCAGAGCATGGAAATTTTGGTGATTGCGAACCGGTGGGCAGCGCAGTATATGAGATGCGTATTC
ACTCGGGTCCGGGCTACAGAGTGTACTTCTCCCGTCGAGGGCCCGTGTTTTATTTACTGCTTGTGGGAGGTGACAAATCG
ACTCAGAAACGGGATATCACACGCGCTATTCAAATGGCGCAAACCATGGGCAATGAGGAGTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10431.98 Da        Isoelectric Point: 4.8096

>AT30872 WP_109752223.1 NZ_AP014703:c793238-792948 [Pseudomonas sp. St290]
MTEEFTRFDAATYLKTPEEMAAYLDACFEEDAGDGVLVRAALNDIARAKGMTQIARDAGLGRESLYKALGSAGNPEFTTI
MKVMKVLGLRLHATTI

Download         Length: 291 bp

>AT30872 NZ_AP014703:c793238-792948 [Pseudomonas sp. St290]
ATGACCGAGGAATTCACACGTTTCGATGCAGCCACCTACCTCAAGACGCCTGAGGAAATGGCCGCATATCTGGATGCCTG
TTTTGAAGAAGATGCGGGTGACGGCGTACTGGTTCGAGCAGCTCTTAACGATATCGCCAGGGCAAAAGGCATGACGCAAA
TTGCCCGTGATGCGGGCCTGGGGCGAGAGAGTCTTTACAAAGCACTGGGAAGTGCGGGTAATCCAGAGTTCACAACTATC
ATGAAAGTCATGAAAGTTTTGGGCTTGAGGTTACATGCTACAACCATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References