Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 6005741..6006260 Replicon chromosome
Accession NZ_AP014637
Organism Pseudomonas sp. StFLB209

Toxin (Protein)


Gene name relE Uniprot ID A0A077LRM0
Locus tag PSCI_RS26660 Protein ID WP_045492887.1
Coordinates 6005741..6006031 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A077LSA9
Locus tag PSCI_RS26665 Protein ID WP_045492890.1
Coordinates 6006021..6006260 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSCI_RS26630 6001785..6002648 + 864 WP_045492873.1 curli production assembly/transporter CsgG -
PSCI_RS26635 6002667..6003173 + 507 WP_045492876.1 curlin-associated protein -
PSCI_RS26640 6003179..6003472 + 294 WP_045495061.1 hypothetical protein -
PSCI_RS26645 6003534..6003929 + 396 WP_045492879.1 DUF1311 domain-containing protein -
PSCI_RS29480 6003935..6004078 + 144 WP_158497600.1 hypothetical protein -
PSCI_RS26650 6004084..6004440 + 357 WP_045492882.1 GFA family protein -
PSCI_RS29365 6004603..6004824 + 222 WP_144403349.1 hypothetical protein -
PSCI_RS26655 6004899..6005453 - 555 WP_144403350.1 hypothetical protein -
PSCI_RS26660 6005741..6006031 - 291 WP_045492887.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSCI_RS26665 6006021..6006260 - 240 WP_045492890.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PSCI_RS26670 6006583..6007803 - 1221 WP_045495064.1 SGNH/GDSL hydrolase family protein -
PSCI_RS26675 6007847..6008968 - 1122 WP_045492894.1 DUF459 domain-containing protein -
PSCI_RS26680 6008955..6010358 - 1404 WP_045492897.1 MBOAT family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-65)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11181.03 Da        Isoelectric Point: 10.4613

>T30813 WP_045492887.1 NZ_AP014637:c6006031-6005741 [Pseudomonas sp. StFLB209]
MTFSLEFDARALKEWHKLGDTIRQQLKKKLAAVLVNPRVDANRLQGFADCYKIKLRSSGYRLVYQVIDHEVVVFVVAVDK
RERSQVYTKAAERLKN

Download         Length: 291 bp

>T30813 NZ_AP014637:c6006031-6005741 [Pseudomonas sp. StFLB209]
ATGACCTTTAGTCTTGAGTTTGATGCGAGGGCGTTGAAGGAGTGGCACAAGCTTGGCGATACCATTCGCCAGCAACTCAA
AAAGAAGCTCGCTGCAGTGCTGGTCAATCCACGTGTTGACGCCAACCGACTGCAGGGGTTTGCAGACTGCTACAAGATTA
AATTACGCAGCAGCGGATATCGCTTGGTCTACCAGGTTATTGACCATGAAGTGGTCGTGTTCGTGGTGGCAGTAGACAAG
CGTGAACGTAGCCAGGTTTATACCAAGGCGGCTGAACGCTTGAAAAACTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9164.55 Da        Isoelectric Point: 4.6437

>AT30813 WP_045492890.1 NZ_AP014637:c6006260-6006021 [Pseudomonas sp. StFLB209]
MASINIRIDDDLKLRAYRELERLGVTPSELMRQALQYVAERGQLPFRPVLVTEEDEALLTTLRERLAEPQRVKVSLDDL

Download         Length: 240 bp

>AT30813 NZ_AP014637:c6006260-6006021 [Pseudomonas sp. StFLB209]
ATGGCGTCCATCAACATCCGTATCGACGATGATCTGAAACTGCGGGCTTACCGGGAGCTGGAGAGGCTTGGCGTTACCCC
CTCCGAACTGATGCGTCAGGCGCTGCAATATGTGGCAGAACGGGGGCAGTTACCTTTCAGGCCGGTTTTGGTTACCGAAG
AGGATGAAGCGCTACTGACAACACTGCGTGAGCGGCTTGCTGAACCTCAGCGAGTAAAGGTTTCACTGGATGACCTTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A077LRM0

Antitoxin

Source ID Structure
AlphaFold DB A0A077LSA9

References