Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 5980134..5980795 Replicon chromosome
Accession NZ_AP014637
Organism Pseudomonas sp. StFLB209

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PSCI_RS26540 Protein ID WP_045492837.1
Coordinates 5980388..5980795 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A077LPQ7
Locus tag PSCI_RS26535 Protein ID WP_045492834.1
Coordinates 5980134..5980376 (+) Length 81 a.a.

Genomic Context

PSCI_RS26525PSCI_RS26535PSCI_RS26540PSCI_RS26545PSCI_RS26550PSCI_RS26555PSCI_RS26560PSCI_RS26565PSCI_RS26530
Location: 5975587..5976375 (789 bp)
Type: Others
Protein ID: WP_045492831.1
Location: 5980134..5980376 (243 bp)
Type: Antitoxin
Protein ID: WP_045492834.1
Location: 5980388..5980795 (408 bp)
Type: Toxin
Protein ID: WP_045492837.1
Location: 5980970..5981791 (822 bp)
Type: Others
Protein ID: WP_045492840.1
Location: 5981793..5982683 (891 bp)
Type: Others
Protein ID: WP_045492843.1
Location: 5982749..5983357 (609 bp)
Type: Others
Protein ID: WP_084710151.1
Location: 5983357..5984010 (654 bp)
Type: Others
Protein ID: WP_045492846.1
Location: 5984497..5985009 (513 bp)
Type: Others
Protein ID: Protein_5283
Location: 5976513..5979710 (3198 bp)
Type: Others
Protein ID: WP_084710149.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PSCI_RS265255975587..5976375+789WP_045492831.1substrate-binding domain-containing protein-
PSCI_RS265305976513..5979710-3198WP_084710149.1glycosyltransferase-
PSCI_RS265355980134..5980376+243WP_045492834.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
PSCI_RS265405980388..5980795+408WP_045492837.1type II toxin-antitoxin system VapC family toxinToxin
PSCI_RS265455980970..5981791+822WP_045492840.1NAD(P)-dependent oxidoreductase-
PSCI_RS265505981793..5982683+891WP_045492843.1SMP-30/gluconolactonase/LRE family protein-
PSCI_RS265555982749..5983357+609WP_084710151.1sigma-70 family RNA polymerase sigma factor-
PSCI_RS265605983357..5984010+654WP_045492846.1ChrR family anti-sigma-E factor-
PSCI_RS265655984497..5985009+513Protein_5283transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--5984611..5985009398


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15034.53 Da        Isoelectric Point: 8.5149

>T30812 WP_045492837.1 NZ_AP014637:5980388-5980795 [Pseudomonas sp. StFLB209]
MSPLYMLDTNMVSHIIKGTYPGVQKHLLNTPMDHICISAVTLGELRYGLAKRPDATRLHALVQAFLVRIDVLPWDSHVAN
CYGDLRASMERVGKPLGNLDMMIAAHAKATNVALISNDQAFRQIKGLHTLDWTKD

Download         Length: 408 bp

>T30812 NZ_AP014637:5980388-5980795 [Pseudomonas sp. StFLB209]
ATGAGTCCGCTGTATATGCTCGATACAAACATGGTCAGCCATATCATCAAGGGCACTTACCCTGGCGTGCAGAAGCATCT
GCTCAATACGCCCATGGATCACATATGCATCTCGGCGGTTACTCTGGGTGAATTACGCTATGGCCTGGCCAAGCGACCTG
ACGCGACGCGCCTGCACGCACTCGTGCAGGCGTTTCTGGTTCGCATAGATGTTTTGCCTTGGGACAGCCATGTCGCCAAC
TGCTATGGCGACCTGCGGGCCTCTATGGAACGCGTTGGCAAACCGCTCGGCAATCTGGACATGATGATTGCCGCTCATGC
CAAAGCGACCAATGTTGCGCTGATCAGCAATGACCAGGCATTCAGACAGATCAAGGGTCTGCATACGCTCGACTGGACCA
AGGATTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9311.50 Da        Isoelectric Point: 6.4564

>AT30812 WP_045492834.1 NZ_AP014637:5980134-5980376 [Pseudomonas sp. StFLB209]
MHHVAKLFNNGRSQAVRLPASFRFDCKEVYIRQDPTTGDVILSRKPGTWDGFFELLKDSKVPDDFMSDRQDLPPQERDPF

Download         Length: 243 bp

>AT30812 NZ_AP014637:5980134-5980376 [Pseudomonas sp. StFLB209]
ATGCACCACGTTGCCAAACTGTTCAACAACGGCAGAAGTCAGGCTGTGCGTCTCCCGGCGTCGTTTCGATTCGATTGCAA
GGAAGTCTATATCCGCCAGGACCCCACAACAGGTGACGTCATTCTTTCGCGAAAGCCGGGTACCTGGGACGGTTTTTTTG
AACTCTTGAAAGACAGCAAGGTGCCCGACGACTTCATGTCTGATCGCCAGGATCTGCCACCTCAAGAACGCGATCCATTT
TGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A077LPQ7

References