Detailed information of TA system TA030811

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/-
• Location: 5402330..5402898
• Replicon: chromosome
• Accession: NZ_AP014637
• Organism: Pseudomonas sp. StFLB209

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: PSCI_RS24030
• Protein ID: WP_173426700.1
• Coordinates: 5402527..5402898 (+)
• Length: 124 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A0A077LMJ3
• Locus tag: PSCI_RS24025
• Protein ID: WP_045494840.1
• Coordinates: 5402330..5402530 (+)
• Length: 67 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PSCI_RS24010	5398433..5399866	-	1434	WP_045491843.1	cytosine permease	-
PSCI_RS24015	5400525..5401010	+	486	WP_045491844.1	flavin reductase family protein	-
PSCI_RS24020	5401101..5402138	+	1038	WP_045491846.1	LLM class flavin-dependent oxidoreductase	-
PSCI_RS24025	5402330..5402530	+	201	WP_045494840.1	type II toxin-antitoxin system VapB family antitoxin	Antitoxin
PSCI_RS24030	5402527..5402898	+	372	WP_173426700.1	PIN domain-containing protein	Toxin
PSCI_RS24035	5403059..5404384	-	1326	WP_052483507.1	ammonium transporter	-
PSCI_RS24040	5404541..5405878	-	1338	WP_045491848.1	FMN-binding glutamate synthase family protein	-
PSCI_RS24045	5405894..5406577	-	684	WP_045491850.1	protein glxC	-
PSCI_RS24050	5406590..5407495	-	906	WP_045491852.1	glutamine amidotransferase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	5397735..5398148	413

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-113)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 124 a.a.
• Molecular weight: 13894.18 Da
• Isoelectric Point: 7.0376

>T30811 WP_173426700.1 NZ_AP014637:5402527-5402898 [Pseudomonas sp. StFLB209]
MMDVLIDTSIWVAHFRSYNPGLSNLLQQDRVLIHPMVMGELACGTPPERTRTLADLSSLKHCQQPTWTEVMTFVEQHKLY
GLGCGLVDMTLLASALITRAHLWTLDKRLASLATRLQINHQPD

Nucleotide

• Length: 372 bp

>T30811 NZ_AP014637:5402527-5402898 [Pseudomonas sp. StFLB209]
ATGATGGATGTGCTTATCGATACCTCTATCTGGGTGGCTCACTTTCGCAGCTACAACCCGGGCCTTTCGAACTTGCTTCA
ACAGGACCGGGTGCTGATCCACCCCATGGTTATGGGTGAACTGGCGTGCGGTACACCACCTGAGCGGACTCGAACGCTGG
CAGATCTGTCCAGTTTGAAGCACTGCCAGCAACCCACATGGACCGAAGTAATGACTTTCGTGGAGCAGCACAAGCTCTAC
GGTTTGGGGTGCGGGCTGGTGGACATGACACTGCTGGCATCAGCCTTGATCACTCGGGCGCATTTGTGGACGCTGGACAA
ACGACTGGCCAGCCTGGCCACACGCTTGCAGATCAACCACCAGCCCGACTGA

Antitoxin

Protein

• Length: 67 a.a.
• Molecular weight: 7400.46 Da
• Isoelectric Point: 4.5045

>AT30811 WP_045494840.1 NZ_AP014637:5402330-5402530 [Pseudomonas sp. StFLB209]
MRTTVTIDDALYERALEVADPNMDKAELFREAVQMFVRIQAAKRLAALGSAMPSMEDIPRRSDASE

Nucleotide

• Length: 201 bp

>AT30811 NZ_AP014637:5402330-5402530 [Pseudomonas sp. StFLB209]
ATGAGAACGACCGTTACGATTGATGACGCCTTGTATGAACGTGCCCTTGAAGTCGCAGACCCTAATATGGACAAGGCCGA
GCTTTTTCGTGAGGCCGTGCAGATGTTTGTCCGTATTCAGGCAGCAAAGCGTTTGGCAGCCCTTGGCTCTGCAATGCCCT
CAATGGAGGATATCCCCCGTCGAAGTGATGCATCCGAATGA

Structures

Antitoxin

• AlphaFold DB: A0A077LMJ3