Detailed information of TA system TA030806

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-RHH
• Location: 776807..777345
• Replicon: chromosome
• Accession: NZ_AP014636
• Organism: Vibrio tritonius strain AM2

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: JCM16456_RS18720
• Protein ID: WP_068717361.1
• Coordinates: 776807..777106 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: JCM16456_RS18725
• Protein ID: WP_068717363.1
• Coordinates: 777103..777345 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JCM16456_RS18695	772186..773028	+	843	WP_068717353.1	hypothetical protein	-
JCM16456_RS18700	773630..774097	+	468	WP_068717355.1	hypothetical protein	-
JCM16456_RS23855	774081..774248	+	168	WP_156430600.1	hypothetical protein	-
JCM16456_RS18705	774719..776038	+	1320	WP_068717357.1	group II intron reverse transcriptase/maturase	-
JCM16456_RS18710	776125..776415	-	291	WP_068717358.1	type II toxin-antitoxin system RelE/ParE family toxin	-
JCM16456_RS18715	776405..776653	-	249	WP_068717359.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
JCM16456_RS18720	776807..777106	-	300	WP_068717361.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
JCM16456_RS18725	777103..777345	-	243	WP_068717363.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
JCM16456_RS18730	777506..777796	-	291	WP_068717366.1	type II toxin-antitoxin system RelE/ParE family toxin	-
JCM16456_RS18735	777786..778034	-	249	WP_068717367.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
JCM16456_RS18740	778236..778744	+	509	Protein_698	rod shape-determining protein	-
JCM16456_RS18745	778855..779145	-	291	WP_068717369.1	type II toxin-antitoxin system RelE/ParE family toxin	-
JCM16456_RS18750	779138..779359	-	222	WP_068717371.1	hypothetical protein	-
JCM16456_RS18755	779622..780041	+	420	WP_068719041.1	GNAT family N-acetyltransferase	-
JCM16456_RS18760	780157..780789	+	633	WP_068719043.1	class I SAM-dependent methyltransferase	-
JCM16456_RS23860	781003..781128	+	126	WP_156430644.1	aspartate/glutamate racemase family protein	-
JCM16456_RS18770	781746..782096	+	351	WP_068719045.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integron	-	-	772186..779145	6959

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-92)

Antitoxin

• Antitoxin ParD (1-78)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11626.39 Da
• Isoelectric Point: 10.2950

>T30806 WP_068717361.1 NZ_AP014636:c777106-776807 [Vibrio tritonius]
MKPFQLTNKAKSDLKDIALFTSRRWGREQRNVYLKQFDESFWLLAENPDIGKACDDIRKGYRKFPQGSHVIFYQQIGSQN
IQIIRILHKSMDVHPIFGG

Nucleotide

• Length: 300 bp

>T30806 NZ_AP014636:c777106-776807 [Vibrio tritonius]
ATGAAACCATTCCAACTCACCAATAAGGCGAAGTCCGATTTAAAAGACATAGCCCTCTTTACTTCTCGACGCTGGGGCAG
AGAACAGCGTAACGTTTATCTTAAACAATTTGACGAATCTTTTTGGCTACTTGCTGAAAATCCCGATATTGGTAAAGCAT
GTGACGATATCAGAAAAGGATACCGGAAATTTCCTCAAGGAAGTCACGTTATTTTTTATCAACAAATTGGCAGTCAAAAC
ATTCAAATTATCAGGATATTGCACAAAAGCATGGATGTTCATCCGATCTTTGGCGGATAA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9027.03 Da
• Isoelectric Point: 4.3566

>AT30806 WP_068717363.1 NZ_AP014636:c777345-777103 [Vibrio tritonius]
MAKNTSITLGEHFDGFIANQIKSGRYGSASEVIRSALRLLETQETKMNTLRQLLVEGEESGMADYDLDSFINELDNEERK

Nucleotide

• Length: 243 bp

>AT30806 NZ_AP014636:c777345-777103 [Vibrio tritonius]
ATGGCTAAAAATACTAGTATTACTTTAGGCGAACACTTCGATGGTTTCATTGCGAACCAAATCAAAAGTGGGCGCTACGG
TTCTGCAAGTGAAGTAATTCGTTCTGCTTTGCGCTTGCTTGAAACCCAAGAAACAAAAATGAATACACTACGCCAACTTC
TGGTTGAAGGCGAAGAAAGTGGCATGGCCGACTATGACCTTGATTCGTTTATCAATGAACTCGATAACGAAGAAAGAAAA
TGA