Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-YafN |
| Location | 776125..776653 | Replicon | chromosome |
| Accession | NZ_AP014636 | ||
| Organism | Vibrio tritonius strain AM2 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | JCM16456_RS18710 | Protein ID | WP_068717358.1 |
| Coordinates | 776125..776415 (-) | Length | 97 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | JCM16456_RS18715 | Protein ID | WP_068717359.1 |
| Coordinates | 776405..776653 (-) | Length | 83 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JCM16456_RS18685 | 771351..771605 | + | 255 | WP_068717350.1 | hypothetical protein | - |
| JCM16456_RS18690 | 771607..772041 | + | 435 | WP_068717351.1 | hypothetical protein | - |
| JCM16456_RS18695 | 772186..773028 | + | 843 | WP_068717353.1 | hypothetical protein | - |
| JCM16456_RS18700 | 773630..774097 | + | 468 | WP_068717355.1 | hypothetical protein | - |
| JCM16456_RS23855 | 774081..774248 | + | 168 | WP_156430600.1 | hypothetical protein | - |
| JCM16456_RS18705 | 774719..776038 | + | 1320 | WP_068717357.1 | group II intron reverse transcriptase/maturase | - |
| JCM16456_RS18710 | 776125..776415 | - | 291 | WP_068717358.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| JCM16456_RS18715 | 776405..776653 | - | 249 | WP_068717359.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| JCM16456_RS18720 | 776807..777106 | - | 300 | WP_068717361.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| JCM16456_RS18725 | 777103..777345 | - | 243 | WP_068717363.1 | type II toxin-antitoxin system ParD family antitoxin | - |
| JCM16456_RS18730 | 777506..777796 | - | 291 | WP_068717366.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| JCM16456_RS18735 | 777786..778034 | - | 249 | WP_068717367.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| JCM16456_RS18740 | 778236..778744 | + | 509 | Protein_698 | rod shape-determining protein | - |
| JCM16456_RS18745 | 778855..779145 | - | 291 | WP_068717369.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| JCM16456_RS18750 | 779138..779359 | - | 222 | WP_068717371.1 | hypothetical protein | - |
| JCM16456_RS18755 | 779622..780041 | + | 420 | WP_068719041.1 | GNAT family N-acetyltransferase | - |
| JCM16456_RS18760 | 780157..780789 | + | 633 | WP_068719043.1 | class I SAM-dependent methyltransferase | - |
| JCM16456_RS23860 | 781003..781128 | + | 126 | WP_156430644.1 | aspartate/glutamate racemase family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integron | - | - | 772186..779145 | 6959 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11281.24 Da Isoelectric Point: 10.5021
>T30805 WP_068717358.1 NZ_AP014636:c776415-776125 [Vibrio tritonius]
MIYKLNFKKSALKEWKKLSSTLQEHFKKKLAERLTNPHVPDSKLSGADNMYKIKLRQSGYRLVYKVEDDIIVVTVLAVGK
RERSDVYHKAMKRLDD
MIYKLNFKKSALKEWKKLSSTLQEHFKKKLAERLTNPHVPDSKLSGADNMYKIKLRQSGYRLVYKVEDDIIVVTVLAVGK
RERSDVYHKAMKRLDD
Download Length: 291 bp
>T30805 NZ_AP014636:c776415-776125 [Vibrio tritonius]
ATGATTTATAAGCTAAATTTTAAAAAATCTGCCCTTAAAGAATGGAAGAAACTCAGTTCTACCTTACAGGAGCATTTTAA
GAAAAAGCTGGCGGAAAGGTTAACTAACCCTCATGTACCAGATTCAAAACTATCTGGAGCTGACAATATGTATAAAATTA
AACTCCGCCAATCAGGTTACCGTTTAGTTTACAAAGTCGAAGATGACATCATCGTAGTCACCGTTTTAGCAGTTGGAAAA
CGTGAACGAAGCGATGTTTATCATAAAGCAATGAAACGCTTGGATGATTGA
ATGATTTATAAGCTAAATTTTAAAAAATCTGCCCTTAAAGAATGGAAGAAACTCAGTTCTACCTTACAGGAGCATTTTAA
GAAAAAGCTGGCGGAAAGGTTAACTAACCCTCATGTACCAGATTCAAAACTATCTGGAGCTGACAATATGTATAAAATTA
AACTCCGCCAATCAGGTTACCGTTTAGTTTACAAAGTCGAAGATGACATCATCGTAGTCACCGTTTTAGCAGTTGGAAAA
CGTGAACGAAGCGATGTTTATCATAAAGCAATGAAACGCTTGGATGATTGA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9156.49 Da Isoelectric Point: 4.0078
>AT30805 WP_068717359.1 NZ_AP014636:c776653-776405 [Vibrio tritonius]
MTTRILADVAASITELKANPMKVATSAYGQPVAILNRNEPAFYCVPAEAYEMMMDKLEDLELLSIAKEREYEESISVNLD
DL
MTTRILADVAASITELKANPMKVATSAYGQPVAILNRNEPAFYCVPAEAYEMMMDKLEDLELLSIAKEREYEESISVNLD
DL
Download Length: 249 bp
>AT30805 NZ_AP014636:c776653-776405 [Vibrio tritonius]
ATGACCACTAGAATCTTAGCTGATGTTGCTGCAAGCATTACAGAATTAAAAGCTAATCCAATGAAAGTTGCTACCAGTGC
TTATGGTCAACCTGTCGCTATTCTTAACCGCAATGAACCTGCTTTTTATTGCGTTCCTGCTGAAGCTTACGAAATGATGA
TGGATAAACTAGAAGATCTAGAACTACTATCCATTGCAAAAGAACGCGAATATGAAGAAAGCATCTCGGTAAACCTTGAT
GATTTATAA
ATGACCACTAGAATCTTAGCTGATGTTGCTGCAAGCATTACAGAATTAAAAGCTAATCCAATGAAAGTTGCTACCAGTGC
TTATGGTCAACCTGTCGCTATTCTTAACCGCAATGAACCTGCTTTTTATTGCGTTCCTGCTGAAGCTTACGAAATGATGA
TGGATAAACTAGAAGATCTAGAACTACTATCCATTGCAAAAGAACGCGAATATGAAGAAAGCATCTCGGTAAACCTTGAT
GATTTATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|