Detailed information of TA system TA030804

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YefM(antitoxin)
• Location: 529421..529986
• Replicon: chromosome
• Accession: NZ_AP014636
• Organism: Vibrio tritonius strain AM2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: JCM16456_RS17540
• Protein ID: WP_068716928.1
• Coordinates: 529421..529708 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: JCM16456_RS17545
• Protein ID: WP_068716929.1
• Coordinates: 529705..529986 (-)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JCM16456_RS17520	526414..527340	+	927	WP_068716922.1	DMT family transporter	-
JCM16456_RS17525	527312..527890	-	579	WP_068716924.1	TetR/AcrR family transcriptional regulator	-
JCM16456_RS17530	528005..528550	-	546	WP_068716926.1	XRE family transcriptional regulator	-
JCM16456_RS17535	529108..529383	+	276	Protein_453	IS110 family transposase	-
JCM16456_RS17540	529421..529708	-	288	WP_068716928.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
JCM16456_RS17545	529705..529986	-	282	WP_068716929.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
JCM16456_RS17550	530400..531410	+	1011	WP_068716930.1	LD-carboxypeptidase	-
JCM16456_RS17555	531474..532631	+	1158	WP_068716932.1	iron-containing alcohol dehydrogenase	-
JCM16456_RS17560	532755..533729	-	975	WP_068716934.1	MBL fold metallo-hydrolase	-
JCM16456_RS17565	533879..534904	-	1026	WP_068716937.1	Gfo/Idh/MocA family oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	529081..529383	302

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-74)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10866.48 Da
• Isoelectric Point: 4.2086

>T30804 WP_068716928.1 NZ_AP014636:c529708-529421 [Vibrio tritonius]
MNVVWSPLALEKLGDAAEFISLDDPVAAENWVNDVFDKTELLGTMPEMGRLVPELHNSNYREIIFGNYRIIYSIGLEIQI
LTIRNCRQILTKDDV

Nucleotide

• Length: 288 bp

>T30804 NZ_AP014636:c529708-529421 [Vibrio tritonius]
ATGAATGTTGTTTGGTCTCCATTAGCACTTGAAAAATTAGGGGATGCAGCTGAATTTATTTCACTTGACGATCCTGTCGC
AGCAGAAAATTGGGTTAATGACGTTTTTGATAAAACAGAATTATTAGGAACAATGCCTGAAATGGGGCGGTTAGTTCCAG
AATTGCATAATTCCAATTATCGGGAAATTATTTTTGGTAACTATCGTATAATTTATAGTATTGGTCTTGAAATACAAATA
CTTACAATAAGAAATTGTCGGCAGATTTTAACAAAAGATGACGTCTGA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10518.07 Da
• Isoelectric Point: 6.3843

>AT30804 WP_068716929.1 NZ_AP014636:c529986-529705 [Vibrio tritonius]
MNRIRFDQDIRPLSEFRSGVASFIKQINETRRPLVITQRGKGVAVVLDVEEYEAMQEKIELLEEMRTAEAQLASGLGISN
EDARASVLGRIKK

Nucleotide

• Length: 282 bp

>AT30804 NZ_AP014636:c529986-529705 [Vibrio tritonius]
ATGAACCGTATCCGTTTTGATCAAGATATCAGACCGTTATCTGAATTTCGTTCAGGTGTGGCTTCATTTATCAAACAAAT
CAATGAGACTAGACGTCCATTAGTCATTACCCAACGGGGAAAAGGTGTTGCTGTTGTTCTAGATGTAGAAGAATACGAAG
CAATGCAAGAGAAGATTGAATTACTTGAAGAAATGCGAACAGCAGAAGCCCAACTAGCTTCAGGTCTGGGGATTTCAAAT
GAAGACGCTCGAGCTAGTGTACTGGGGCGCATTAAGAAATGA