Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 2153549..2154111 Replicon chromosome
Accession NZ_AP014635
Organism Vibrio tritonius strain AM2

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag JCM16456_RS09550 Protein ID WP_068713994.1
Coordinates 2153809..2154111 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag JCM16456_RS09545 Protein ID WP_068713993.1
Coordinates 2153549..2153791 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JCM16456_RS09510 2148922..2149443 - 522 WP_179946801.1 GNAT family N-acetyltransferase -
JCM16456_RS09515 2149569..2150300 - 732 WP_068713987.1 PhzF family phenazine biosynthesis protein -
JCM16456_RS09520 2150450..2151028 - 579 WP_082712329.1 HD domain-containing protein -
JCM16456_RS09525 2151140..2151445 - 306 WP_068713989.1 hypothetical protein -
JCM16456_RS09530 2151432..2151743 - 312 WP_068713990.1 hypothetical protein -
JCM16456_RS09535 2151882..2152508 - 627 WP_068713991.1 LysE family translocator -
JCM16456_RS09540 2152616..2153146 - 531 WP_068713992.1 histidine phosphatase family protein -
JCM16456_RS09545 2153549..2153791 + 243 WP_068713993.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JCM16456_RS09550 2153809..2154111 + 303 WP_068713994.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JCM16456_RS09555 2154495..2155757 + 1263 WP_068713995.1 IS110 family transposase -
JCM16456_RS09560 2155799..2156191 - 393 WP_068713996.1 hypothetical protein -
JCM16456_RS09565 2156321..2156932 - 612 WP_068713997.1 deoxynucleoside kinase -
JCM16456_RS09570 2157044..2157460 - 417 WP_068713998.1 GNAT family N-acetyltransferase -
JCM16456_RS09575 2157607..2157996 - 390 WP_068713999.1 MAPEG family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2150450..2163125 12675


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-52)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11485.15 Da        Isoelectric Point: 9.7094

>T30803 WP_068713994.1 NZ_AP014635:2153809-2154111 [Vibrio tritonius]
MPNKSYKLSRLAQGHLLKIKNYTVENFSDTQWTKYKAALLTAFQALADNPELGKNCYDIYRSGFYFHVGKHTAYYTKEDG
FILIVAVLGQSQLPQKHLHS

Download         Length: 303 bp

>T30803 NZ_AP014635:2153809-2154111 [Vibrio tritonius]
ATGCCGAATAAATCTTATAAATTGAGCCGTCTAGCTCAAGGACATTTGCTCAAAATTAAAAATTACACTGTCGAAAATTT
TTCAGATACGCAATGGACTAAATATAAAGCGGCTTTACTTACTGCTTTTCAAGCTTTAGCTGATAACCCTGAATTAGGGA
AAAATTGTTATGACATTTACCGCAGCGGCTTCTACTTTCATGTGGGTAAGCACACCGCTTACTATACCAAAGAAGATGGC
TTTATCCTCATAGTTGCAGTACTGGGGCAATCCCAACTTCCTCAGAAACATCTACATTCATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8944.16 Da        Isoelectric Point: 5.0914

>AT30803 WP_068713993.1 NZ_AP014635:2153549-2153791 [Vibrio tritonius]
MRTLTANDAKRNFGELLLSAQREPIKISKNSKDAVVVISIQDFEELEAMKADYLKHCFESAKKDLANGNVVDGENFLNSL

Download         Length: 243 bp

>AT30803 NZ_AP014635:2153549-2153791 [Vibrio tritonius]
ATGCGCACACTAACAGCCAATGACGCCAAACGAAACTTCGGTGAACTCCTTTTGAGTGCCCAACGTGAACCCATAAAAAT
TAGCAAAAACAGCAAAGACGCTGTTGTTGTTATTTCCATTCAAGATTTCGAAGAACTTGAAGCGATGAAAGCTGATTACC
TTAAACACTGTTTTGAATCAGCAAAAAAAGATTTAGCCAACGGAAACGTCGTTGATGGTGAAAACTTCCTAAATTCTCTT
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References