30800

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1161777..1162317 Replicon chromosome
Accession NZ_AP014635
Organism Vibrio tritonius strain AM2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JCM16456_RS05295 Protein ID WP_068713044.1
Coordinates 1161777..1162046 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JCM16456_RS05300 Protein ID WP_068713046.1
Coordinates 1162039..1162317 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JCM16456_RS05270 1156948..1157463 - 516 WP_068713035.1 RNA methyltransferase -
JCM16456_RS05275 1157510..1158043 - 534 WP_068713038.1 GNAT family N-acetyltransferase -
JCM16456_RS23575 1158083..1158250 + 168 WP_156430451.1 hypothetical protein -
JCM16456_RS05280 1158438..1159751 + 1314 WP_068713040.1 amidohydrolase -
JCM16456_RS05285 1160098..1160886 + 789 WP_068713042.1 outer membrane beta-barrel protein -
JCM16456_RS05290 1160981..1161670 - 690 WP_082712318.1 monofunctional biosynthetic peptidoglycan transglycosylase -
JCM16456_RS05295 1161777..1162046 - 270 WP_068713044.1 type II toxin-antitoxin system YafQ family toxin Toxin
JCM16456_RS05300 1162039..1162317 - 279 WP_068713046.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
JCM16456_RS05305 1162374..1162898 + 525 WP_082712221.1 LysE family translocator -
JCM16456_RS05310 1163245..1165170 + 1926 WP_068713050.1 FTR1 family iron permease -
JCM16456_RS05315 1165235..1165756 + 522 WP_162266545.1 iron transporter -
JCM16456_RS05320 1165859..1167262 + 1404 WP_068713054.1 DUF2318 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-84)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10332.98 Da        Isoelectric Point: 8.9074

>T30800 WP_068713044.1 NZ_AP014635:c1162046-1161777 [Vibrio tritonius]
MYSLEYSTQFKKDFKKITKMPIPDIIEVGNIISKLQRGETLAPQNVDHPLTGNWVGFRDCHVKPDLVLIYRIYNQQLQLA
RIGSHSDLF

Download         Length: 270 bp

>T30800 NZ_AP014635:c1162046-1161777 [Vibrio tritonius]
ATGTATAGTCTCGAGTATTCAACTCAATTTAAGAAAGACTTTAAGAAGATAACTAAAATGCCGATTCCCGATATTATTGA
GGTCGGCAATATCATATCCAAACTTCAGCGAGGGGAAACTCTTGCCCCACAAAATGTAGACCATCCACTCACAGGCAATT
GGGTGGGTTTTAGAGATTGTCACGTCAAACCCGATTTAGTGCTTATTTACCGTATTTATAATCAACAACTACAACTTGCT
CGTATCGGCTCACACAGCGATTTGTTTTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 9973.44 Da        Isoelectric Point: 5.6024

>AT30800 WP_068713046.1 NZ_AP014635:c1162317-1162039 [Vibrio tritonius]
MRTEMLSTRIDHETKVAFTSICDGMGLSTSQAIKLFAKAVINHGGIPFELRVAQPNEITAAAIKELVEGKGHQAESLDAM
FDELTDGKVKNV

Download         Length: 279 bp

>AT30800 NZ_AP014635:c1162317-1162039 [Vibrio tritonius]
ATGAGAACAGAAATGTTGAGCACTCGTATTGATCATGAAACGAAAGTGGCTTTCACTAGCATATGTGATGGGATGGGTTT
AAGTACTTCACAAGCCATTAAATTGTTTGCCAAAGCAGTCATCAATCACGGCGGTATTCCATTCGAACTGCGCGTCGCGC
AACCGAATGAAATCACAGCTGCCGCAATAAAAGAGCTAGTTGAGGGCAAGGGTCACCAAGCAGAATCGCTTGATGCCATG
TTCGATGAGTTGACTGATGGTAAGGTCAAAAATGTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References