Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 6715520..6717228 Replicon chromosome
Accession NZ_AP014628
Organism Pseudomonas sp. St29

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag PST29_RS30095 Protein ID WP_060845002.1
Coordinates 6715520..6716398 (+) Length 293 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag PST29_RS30100 Protein ID WP_060845003.1
Coordinates 6716395..6717228 (+) Length 278 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PST29_RS30070 6711504..6712355 + 852 WP_082729311.1 ABC transporter ATP-binding protein -
PST29_RS30075 6712395..6713396 + 1002 WP_060844999.1 ABC transporter substrate-binding protein -
PST29_RS30080 6713426..6714202 + 777 WP_060845000.1 ABC transporter permease -
PST29_RS30085 6714202..6714966 + 765 WP_060845192.1 SDR family oxidoreductase -
PST29_RS30090 6714979..6715515 + 537 WP_060845001.1 cupin domain-containing protein -
PST29_RS30095 6715520..6716398 + 879 WP_060845002.1 alpha/beta hydrolase Toxin
PST29_RS30100 6716395..6717228 + 834 WP_060845003.1 IclR family transcriptional regulator Antitoxin
PST29_RS30105 6717230..6718027 + 798 WP_060845004.1 SDR family oxidoreductase -
PST29_RS30110 6718020..6719702 + 1683 WP_060845193.1 thiamine pyrophosphate-binding protein -
PST29_RS30115 6719713..6720516 + 804 WP_060845005.1 aspartate dehydrogenase -
PST29_RS30120 6720619..6722115 + 1497 WP_060845006.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(45-276)

Antitoxin

Transcription regulator IclR, N-terminal

(19-68)


Sequences

Toxin        


Download         Length: 293 a.a.        Molecular weight: 30661.34 Da        Isoelectric Point: 7.7365

>T30797 WP_060845002.1 NZ_AP014628:6715520-6716398 [Pseudomonas sp. St29]
MFPGLSQPVATADLQAQLARDFPQRLVTASGGLQALREGGAGPALVLLHGIGSGAASWLEVAQHLAPKARVIAWDAPGYG
DSSPLESPAPKAEHYAARLLQMLDALEIEQCVLVGHSLGALPALALARSAQARRVSRLLLISPAQGYGAPALAEQGRQVR
QQRLDTLERLGIAGLADQRSAQMLSPTATPQALAWVRWNMARLNPTGYRQAIELLCGDDLLRHGPPGMPCEVHCGAADRI
TPAEGCLTLAKALGARFNLIANAGHASPVEQPLVVAGLLARAIEESLTGRPL

Download         Length: 879 bp

>T30797 NZ_AP014628:6715520-6716398 [Pseudomonas sp. St29]
ATGTTCCCAGGCCTCTCTCAACCGGTAGCGACGGCGGACCTGCAAGCCCAGCTGGCCCGGGACTTTCCCCAGCGCCTGGT
GACGGCCAGCGGCGGCCTCCAGGCCCTGCGTGAAGGCGGCGCGGGGCCGGCGCTGGTGCTGCTGCACGGCATCGGCTCCG
GGGCGGCCTCCTGGCTGGAAGTCGCACAGCACCTGGCGCCCAAGGCCCGGGTCATTGCCTGGGACGCGCCCGGCTACGGT
GATTCCAGCCCGCTGGAATCCCCCGCGCCGAAGGCCGAGCACTACGCCGCCCGGCTGCTGCAGATGCTCGACGCGCTGGA
GATCGAGCAATGCGTGCTGGTGGGGCACTCCCTGGGCGCGTTGCCGGCCCTGGCCTTGGCCCGCAGCGCCCAGGCCCGGC
GGGTCAGCCGCTTGCTGCTGATCAGCCCGGCCCAGGGCTACGGCGCGCCAGCGCTGGCCGAACAGGGCCGGCAGGTGCGC
CAACAACGCCTGGACACGCTAGAGCGCCTGGGCATCGCCGGCCTAGCCGATCAGCGCAGCGCCCAGATGCTTTCGCCCAC
CGCCACGCCCCAGGCCCTGGCCTGGGTGCGCTGGAACATGGCCCGCCTGAACCCCACCGGGTATCGCCAGGCCATCGAGC
TGTTGTGTGGTGACGACCTGCTGCGCCATGGCCCACCCGGCATGCCCTGCGAAGTGCATTGCGGCGCAGCCGACCGCATC
ACCCCGGCCGAGGGTTGCCTGACCCTGGCCAAGGCACTAGGCGCACGCTTCAACCTGATCGCCAACGCGGGCCACGCCAG
CCCCGTCGAACAACCGCTGGTGGTGGCGGGCCTGCTGGCCCGCGCCATCGAAGAATCCCTGACAGGTAGACCCCTATGA

Antitoxin


Download         Length: 278 a.a.        Molecular weight: 30478.93 Da        Isoelectric Point: 6.6467

>AT30797 WP_060845003.1 NZ_AP014628:6716395-6717228 [Pseudomonas sp. St29]
MNDADLLKDPQDKYIVPGLERGLLLLCEFSRSNRTLTAPELARRLALPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDRLNYPSNLVVRDGRSIVYVAKVSPPSVFSSAVSVGTRLPAHATVLGRVLLGDLSLA
ELRELYPEEHLEQHSPSTPNTVMALFDMVQADRQRGFVSGEGFFEPSISTVAAPVRDQSGSIVAALGVTIATAQVGHINY
NELLLQVRRSADELSRLLNYNSAAHDGQPRVTALMRD

Download         Length: 834 bp

>AT30797 NZ_AP014628:6716395-6717228 [Pseudomonas sp. St29]
ATGAACGACGCCGATCTGCTGAAGGACCCTCAGGACAAGTACATCGTCCCAGGCCTGGAACGGGGCCTGTTGCTGCTGTG
CGAATTCAGCCGCAGCAACCGCACCCTCACCGCCCCGGAGCTGGCCCGGCGCCTGGCCCTGCCGCGCTCGACCATCTTCC
GTCTGCTGACCACCCTGGAAACCATGGGTTTCGTGACCCGCAGCGGCAATGAATACCGCCTGGGCATGTCGGTGCTGCGC
CTGGGCTTCGAATACCTGGCGTCGCTGGAGCTCACCGAGCTGGGCCAGCCGCTGCTGGCGCGGCTGTGCGACCGCCTCAA
CTACCCGAGCAACCTGGTGGTGCGCGACGGTCGCTCGATCGTCTACGTGGCCAAGGTTTCGCCACCTTCGGTGTTCTCCA
GCGCGGTCAGCGTCGGCACCCGCCTGCCGGCCCACGCCACGGTGCTCGGCCGGGTGCTGCTGGGGGATTTGTCCCTGGCC
GAGCTGCGCGAGCTGTACCCGGAGGAACACCTGGAACAGCACTCCCCCAGCACGCCAAACACCGTGATGGCGCTGTTCGA
CATGGTCCAGGCCGACCGCCAGCGGGGCTTTGTCAGCGGCGAAGGCTTCTTCGAGCCGAGCATTTCCACGGTGGCGGCCC
CGGTGCGTGATCAGAGCGGCAGCATCGTCGCCGCCTTGGGAGTGACCATCGCCACCGCCCAGGTCGGCCACATCAACTAC
AACGAACTGCTGCTACAGGTACGCCGCAGCGCCGACGAGCTGTCGCGCCTGCTCAACTACAACAGCGCGGCCCATGACGG
GCAGCCGCGGGTCACCGCCTTGATGAGGGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References