Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/HicA-HicB |
Location | 2400416..2401038 | Replicon | chromosome |
Accession | NZ_AP014628 | ||
Organism | Pseudomonas sp. St29 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | - |
Locus tag | PST29_RS10990 | Protein ID | WP_060845091.1 |
Coordinates | 2400856..2401038 (-) | Length | 61 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | - |
Locus tag | PST29_RS10985 | Protein ID | WP_016968754.1 |
Coordinates | 2400416..2400817 (-) | Length | 134 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PST29_RS10965 | 2396043..2396912 | + | 870 | WP_060843048.1 | AraC family transcriptional regulator | - |
PST29_RS10970 | 2396981..2397235 | + | 255 | WP_060843049.1 | hypothetical protein | - |
PST29_RS10975 | 2397284..2397640 | - | 357 | WP_060843050.1 | hypothetical protein | - |
PST29_RS10980 | 2398108..2399733 | + | 1626 | WP_060838487.1 | methyl-accepting chemotaxis protein | - |
PST29_RS10985 | 2400416..2400817 | - | 402 | WP_016968754.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
PST29_RS10990 | 2400856..2401038 | - | 183 | WP_060845091.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
PST29_RS10995 | 2401309..2401854 | + | 546 | WP_060843051.1 | hypothetical protein | - |
PST29_RS11000 | 2402462..2402893 | - | 432 | WP_016968757.1 | carboxymuconolactone decarboxylase family protein | - |
PST29_RS11005 | 2402922..2403542 | - | 621 | WP_060843052.1 | NAD(P)H-dependent oxidoreductase | - |
PST29_RS11010 | 2403539..2403985 | - | 447 | WP_060843053.1 | GNAT family N-acetyltransferase | - |
PST29_RS11015 | 2404073..2405476 | + | 1404 | WP_060843054.1 | PLP-dependent aminotransferase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 61 a.a. Molecular weight: 6846.03 Da Isoelectric Point: 11.1724
>T30792 WP_060845091.1 NZ_AP014628:c2401038-2400856 [Pseudomonas sp. St29]
VQSRQLIKELEAAGWMLERVTGSHHLFQHPYRPDTVPVPHPKKDLPRGTVRAIRKLAGLL
VQSRQLIKELEAAGWMLERVTGSHHLFQHPYRPDTVPVPHPKKDLPRGTVRAIRKLAGLL
Download Length: 183 bp
>T30792 NZ_AP014628:c2401038-2400856 [Pseudomonas sp. St29]
GTGCAAAGCAGACAGTTGATCAAGGAGCTTGAAGCCGCGGGATGGATGCTGGAGCGAGTCACTGGCAGCCATCATCTGTT
CCAGCATCCCTACAGGCCCGACACCGTTCCAGTGCCTCACCCGAAGAAGGATCTGCCCCGGGGAACGGTCAGGGCCATCA
GGAAACTGGCCGGGCTGCTTTAG
GTGCAAAGCAGACAGTTGATCAAGGAGCTTGAAGCCGCGGGATGGATGCTGGAGCGAGTCACTGGCAGCCATCATCTGTT
CCAGCATCCCTACAGGCCCGACACCGTTCCAGTGCCTCACCCGAAGAAGGATCTGCCCCGGGGAACGGTCAGGGCCATCA
GGAAACTGGCCGGGCTGCTTTAG
Antitoxin
Download Length: 134 a.a. Molecular weight: 14572.59 Da Isoelectric Point: 5.5455
>AT30792 WP_016968754.1 NZ_AP014628:c2400817-2400416 [Pseudomonas sp. St29]
VQYPICIEWGDEHTATGIQIPDIPGAVTAGDTFEAAYSAAIEIAHVMLEERARAGQAIPLPSPTGKHRTHPDFAGMGWGM
LEIDITPYLGKTEKVNVTLPGYVIQQIDRFVREHNIKSRSSFLADAAMEKLGR
VQYPICIEWGDEHTATGIQIPDIPGAVTAGDTFEAAYSAAIEIAHVMLEERARAGQAIPLPSPTGKHRTHPDFAGMGWGM
LEIDITPYLGKTEKVNVTLPGYVIQQIDRFVREHNIKSRSSFLADAAMEKLGR
Download Length: 402 bp
>AT30792 NZ_AP014628:c2400817-2400416 [Pseudomonas sp. St29]
GTGCAATATCCCATCTGCATCGAGTGGGGCGACGAACACACCGCCACCGGCATCCAGATTCCCGACATCCCCGGCGCCGT
CACCGCCGGCGACACCTTCGAGGCCGCCTACAGCGCCGCCATCGAGATTGCCCACGTCATGCTCGAAGAACGGGCCCGAG
CCGGGCAGGCCATTCCCCTGCCCTCGCCCACCGGCAAACACCGCACCCACCCCGATTTCGCGGGCATGGGCTGGGGCATG
CTGGAGATCGACATCACGCCTTACCTGGGCAAGACCGAGAAGGTCAACGTGACCTTGCCGGGGTATGTGATTCAGCAGAT
CGACCGCTTCGTCCGCGAGCACAACATCAAGAGCCGCTCGTCCTTCCTGGCCGATGCGGCAATGGAAAAGCTCGGGCGCT
AA
GTGCAATATCCCATCTGCATCGAGTGGGGCGACGAACACACCGCCACCGGCATCCAGATTCCCGACATCCCCGGCGCCGT
CACCGCCGGCGACACCTTCGAGGCCGCCTACAGCGCCGCCATCGAGATTGCCCACGTCATGCTCGAAGAACGGGCCCGAG
CCGGGCAGGCCATTCCCCTGCCCTCGCCCACCGGCAAACACCGCACCCACCCCGATTTCGCGGGCATGGGCTGGGGCATG
CTGGAGATCGACATCACGCCTTACCTGGGCAAGACCGAGAAGGTCAACGTGACCTTGCCGGGGTATGTGATTCAGCAGAT
CGACCGCTTCGTCCGCGAGCACAACATCAAGAGCCGCTCGTCCTTCCTGGCCGATGCGGCAATGGAAAAGCTCGGGCGCT
AA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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