30790

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 734175..734771 Replicon chromosome
Accession NZ_AP014628
Organism Pseudomonas sp. St29

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PST29_RS03250 Protein ID WP_060842361.1
Coordinates 734469..734771 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2T6GFH6
Locus tag PST29_RS03245 Protein ID WP_060842360.1
Coordinates 734175..734465 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PST29_RS03225 730444..732576 - 2133 WP_060842359.1 TonB-dependent copper receptor -
PST29_RS03230 732665..733075 - 411 WP_060837324.1 DUF2946 domain-containing protein -
PST29_RS03235 733133..733612 - 480 WP_173655926.1 copper chaperone PCu(A)C -
PST29_RS03240 733677..734075 - 399 WP_060837325.1 DUF2946 domain-containing protein -
PST29_RS03245 734175..734465 - 291 WP_060842360.1 putative addiction module antidote protein Antitoxin
PST29_RS03250 734469..734771 - 303 WP_060842361.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PST29_RS03255 734945..735673 - 729 WP_060842362.1 cobalt-precorrin-6A reductase -
PST29_RS03260 735670..736767 - 1098 WP_060837329.1 cobalt-precorrin-5B (C(1))-methyltransferase -
PST29_RS03265 736861..738075 - 1215 WP_060842363.1 bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cobalt-precorrin-6B (C(15))-methyltransferase -
PST29_RS03270 738207..739520 + 1314 WP_060842364.1 precorrin-3B synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Uncharacterized protein HI1420

(5-94)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11510.24 Da        Isoelectric Point: 10.4937

>T30790 WP_060842361.1 NZ_AP014628:c734771-734469 [Pseudomonas sp. St29]
MYVFEQTLEFSRWLLHLKDPQGKTRVLARIRAAQLGRFGDCEALGGGVYEMRIHSGPGYRVYFSRRGTVIYLLLIGGDKN
TQRRDIQRARQLAHDLKSEG

Download         Length: 303 bp

>T30790 NZ_AP014628:c734771-734469 [Pseudomonas sp. St29]
ATGTACGTCTTCGAGCAGACCCTGGAGTTCAGCCGCTGGCTCCTGCACCTGAAGGATCCGCAAGGCAAAACCCGTGTACT
GGCCAGGATCCGCGCCGCCCAACTGGGCCGATTCGGCGACTGCGAAGCACTGGGTGGAGGCGTCTACGAGATGCGCATCC
ATAGTGGTCCCGGCTACCGGGTGTACTTCTCGCGCCGGGGCACGGTGATCTACCTGTTGTTGATCGGCGGTGACAAGAAC
ACCCAGAGACGCGATATCCAACGCGCCAGGCAACTGGCCCACGACCTCAAGAGCGAGGGTTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10454.01 Da        Isoelectric Point: 6.4594

>AT30790 WP_060842360.1 NZ_AP014628:c734465-734175 [Pseudomonas sp. St29]
MHTPVTRFDAAEYLKTPEDMVAYLDACFEEDTGDGKLIRAALNDIARARGMTQIARDTGLGRESLYKALGSQGNPEFATI
IKVMKALGLKLHVSPA

Download         Length: 291 bp

>AT30790 NZ_AP014628:c734465-734175 [Pseudomonas sp. St29]
ATGCACACCCCAGTCACCCGCTTCGACGCGGCGGAGTACCTCAAGACCCCTGAAGACATGGTCGCCTACCTCGACGCCTG
CTTCGAGGAAGACACCGGCGACGGCAAGCTGATCCGCGCCGCCCTCAACGATATCGCCCGCGCCCGCGGCATGACCCAGA
TCGCCCGCGATACCGGCCTGGGCCGCGAGAGCCTGTACAAGGCCCTGGGCAGCCAGGGCAATCCCGAGTTCGCAACTATC
ATCAAGGTCATGAAAGCGCTCGGACTCAAGCTCCACGTCAGCCCGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2T6GFH6

References