Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumA-relB/upstrm_HI1419-dnstrm_HI1420 |
Location | 390232..390837 | Replicon | chromosome |
Accession | NZ_AP014628 | ||
Organism | Pseudomonas sp. St29 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | - |
Locus tag | PST29_RS01760 | Protein ID | WP_060842213.1 |
Coordinates | 390232..390522 (+) | Length | 97 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | PST29_RS01765 | Protein ID | WP_060842214.1 |
Coordinates | 390532..390837 (+) | Length | 102 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PST29_RS01730 | 386646..386966 | + | 321 | WP_060837087.1 | hypothetical protein | - |
PST29_RS01735 | 387048..387458 | - | 411 | WP_060837088.1 | hypothetical protein | - |
PST29_RS01740 | 387584..388552 | - | 969 | WP_060842211.1 | alpha/beta fold hydrolase | - |
PST29_RS01745 | 388601..388930 | - | 330 | WP_060837090.1 | hypothetical protein | - |
PST29_RS01750 | 389053..389373 | + | 321 | WP_047301081.1 | isochorismate lyase | - |
PST29_RS01755 | 389478..390059 | + | 582 | WP_060842212.1 | hypothetical protein | - |
PST29_RS01760 | 390232..390522 | + | 291 | WP_060842213.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
PST29_RS01765 | 390532..390837 | + | 306 | WP_060842214.1 | putative addiction module antidote protein | Antitoxin |
PST29_RS01770 | 391062..392102 | + | 1041 | WP_060845059.1 | DMT family transporter | - |
PST29_RS01775 | 392398..392676 | + | 279 | WP_060842215.1 | hypothetical protein | - |
PST29_RS01780 | 392750..393904 | - | 1155 | WP_060842216.1 | Fic family protein | - |
PST29_RS01790 | 394407..394679 | - | 273 | WP_047301095.1 | oxidative damage protection protein | - |
PST29_RS01795 | 394676..395743 | - | 1068 | WP_047301098.1 | A/G-specific adenine glycosylase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 10975.73 Da Isoelectric Point: 10.3337
>T30789 WP_060842213.1 NZ_AP014628:390232-390522 [Pseudomonas sp. St29]
MHTLIQTERYSQWFARLRDARAQARIKARLRRLELGVLGDCKPVGEGVSELRIDYGPGYRLYFVQRGYEVIVLLAGGDKA
TQAADIRIAIRLSREL
MHTLIQTERYSQWFARLRDARAQARIKARLRRLELGVLGDCKPVGEGVSELRIDYGPGYRLYFVQRGYEVIVLLAGGDKA
TQAADIRIAIRLSREL
Download Length: 291 bp
>T30789 NZ_AP014628:390232-390522 [Pseudomonas sp. St29]
ATGCACACGCTTATTCAGACAGAGCGTTATAGCCAGTGGTTTGCCAGGCTGAGGGACGCTCGGGCACAGGCTCGGATCAA
AGCTCGACTTCGTCGACTGGAGTTGGGGGTTTTGGGTGACTGCAAGCCGGTGGGTGAGGGGGTATCTGAGTTGCGGATAG
ATTATGGGCCGGGTTATCGACTGTATTTCGTGCAGCGCGGCTATGAAGTGATTGTTCTGCTGGCCGGTGGTGACAAGGCG
ACTCAGGCCGCTGATATAAGGATTGCCATCAGGCTGTCCCGTGAGCTCTAG
ATGCACACGCTTATTCAGACAGAGCGTTATAGCCAGTGGTTTGCCAGGCTGAGGGACGCTCGGGCACAGGCTCGGATCAA
AGCTCGACTTCGTCGACTGGAGTTGGGGGTTTTGGGTGACTGCAAGCCGGTGGGTGAGGGGGTATCTGAGTTGCGGATAG
ATTATGGGCCGGGTTATCGACTGTATTTCGTGCAGCGCGGCTATGAAGTGATTGTTCTGCTGGCCGGTGGTGACAAGGCG
ACTCAGGCCGCTGATATAAGGATTGCCATCAGGCTGTCCCGTGAGCTCTAG
Antitoxin
Download Length: 102 a.a. Molecular weight: 10795.52 Da Isoelectric Point: 5.6772
>AT30789 WP_060842214.1 NZ_AP014628:390532-390837 [Pseudomonas sp. St29]
MTKIKLSKWDVVDHLKTEQDMALYLEACLEENDPVLLAAALGDIARARGMSQLARDTGLTREGLYKALSADGNPSLATIM
KVMGALGIKLHAEVGTVQQGG
MTKIKLSKWDVVDHLKTEQDMALYLEACLEENDPVLLAAALGDIARARGMSQLARDTGLTREGLYKALSADGNPSLATIM
KVMGALGIKLHAEVGTVQQGG
Download Length: 306 bp
>AT30789 NZ_AP014628:390532-390837 [Pseudomonas sp. St29]
ATGACCAAGATAAAACTGAGCAAGTGGGATGTAGTCGATCACTTGAAGACTGAACAGGACATGGCTCTTTACCTTGAAGC
CTGTCTGGAGGAGAACGATCCCGTGCTGCTGGCTGCGGCCTTGGGCGATATCGCGCGAGCGCGTGGGATGTCGCAGCTAG
CCCGAGATACTGGCCTGACTCGTGAGGGGCTTTACAAGGCCCTATCAGCTGATGGCAACCCCAGTTTGGCGACCATCATG
AAGGTCATGGGCGCCTTGGGTATAAAGCTGCATGCTGAGGTCGGTACGGTGCAGCAAGGCGGCTGA
ATGACCAAGATAAAACTGAGCAAGTGGGATGTAGTCGATCACTTGAAGACTGAACAGGACATGGCTCTTTACCTTGAAGC
CTGTCTGGAGGAGAACGATCCCGTGCTGCTGGCTGCGGCCTTGGGCGATATCGCGCGAGCGCGTGGGATGTCGCAGCTAG
CCCGAGATACTGGCCTGACTCGTGAGGGGCTTTACAAGGCCCTATCAGCTGATGGCAACCCCAGTTTGGCGACCATCATG
AAGGTCATGGGCGCCTTGGGTATAAAGCTGCATGCTGAGGTCGGTACGGTGCAGCAAGGCGGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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