Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 390232..390837 Replicon chromosome
Accession NZ_AP014628
Organism Pseudomonas sp. St29

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PST29_RS01760 Protein ID WP_060842213.1
Coordinates 390232..390522 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PST29_RS01765 Protein ID WP_060842214.1
Coordinates 390532..390837 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PST29_RS01730 386646..386966 + 321 WP_060837087.1 hypothetical protein -
PST29_RS01735 387048..387458 - 411 WP_060837088.1 hypothetical protein -
PST29_RS01740 387584..388552 - 969 WP_060842211.1 alpha/beta fold hydrolase -
PST29_RS01745 388601..388930 - 330 WP_060837090.1 hypothetical protein -
PST29_RS01750 389053..389373 + 321 WP_047301081.1 isochorismate lyase -
PST29_RS01755 389478..390059 + 582 WP_060842212.1 hypothetical protein -
PST29_RS01760 390232..390522 + 291 WP_060842213.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PST29_RS01765 390532..390837 + 306 WP_060842214.1 putative addiction module antidote protein Antitoxin
PST29_RS01770 391062..392102 + 1041 WP_060845059.1 DMT family transporter -
PST29_RS01775 392398..392676 + 279 WP_060842215.1 hypothetical protein -
PST29_RS01780 392750..393904 - 1155 WP_060842216.1 Fic family protein -
PST29_RS01790 394407..394679 - 273 WP_047301095.1 oxidative damage protection protein -
PST29_RS01795 394676..395743 - 1068 WP_047301098.1 A/G-specific adenine glycosylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-90)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10975.73 Da        Isoelectric Point: 10.3337

>T30789 WP_060842213.1 NZ_AP014628:390232-390522 [Pseudomonas sp. St29]
MHTLIQTERYSQWFARLRDARAQARIKARLRRLELGVLGDCKPVGEGVSELRIDYGPGYRLYFVQRGYEVIVLLAGGDKA
TQAADIRIAIRLSREL

Download         Length: 291 bp

>T30789 NZ_AP014628:390232-390522 [Pseudomonas sp. St29]
ATGCACACGCTTATTCAGACAGAGCGTTATAGCCAGTGGTTTGCCAGGCTGAGGGACGCTCGGGCACAGGCTCGGATCAA
AGCTCGACTTCGTCGACTGGAGTTGGGGGTTTTGGGTGACTGCAAGCCGGTGGGTGAGGGGGTATCTGAGTTGCGGATAG
ATTATGGGCCGGGTTATCGACTGTATTTCGTGCAGCGCGGCTATGAAGTGATTGTTCTGCTGGCCGGTGGTGACAAGGCG
ACTCAGGCCGCTGATATAAGGATTGCCATCAGGCTGTCCCGTGAGCTCTAG

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10795.52 Da        Isoelectric Point: 5.6772

>AT30789 WP_060842214.1 NZ_AP014628:390532-390837 [Pseudomonas sp. St29]
MTKIKLSKWDVVDHLKTEQDMALYLEACLEENDPVLLAAALGDIARARGMSQLARDTGLTREGLYKALSADGNPSLATIM
KVMGALGIKLHAEVGTVQQGG

Download         Length: 306 bp

>AT30789 NZ_AP014628:390532-390837 [Pseudomonas sp. St29]
ATGACCAAGATAAAACTGAGCAAGTGGGATGTAGTCGATCACTTGAAGACTGAACAGGACATGGCTCTTTACCTTGAAGC
CTGTCTGGAGGAGAACGATCCCGTGCTGCTGGCTGCGGCCTTGGGCGATATCGCGCGAGCGCGTGGGATGTCGCAGCTAG
CCCGAGATACTGGCCTGACTCGTGAGGGGCTTTACAAGGCCCTATCAGCTGATGGCAACCCCAGTTTGGCGACCATCATG
AAGGTCATGGGCGCCTTGGGTATAAAGCTGCATGCTGAGGTCGGTACGGTGCAGCAAGGCGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References