Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 2917045..2918299 | Replicon | chromosome |
| Accession | NZ_AP014627 | ||
| Organism | Pseudomonas sp. Os17 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | A0A0D6BGU4 |
| Locus tag | POS17_RS13260 | Protein ID | WP_060838973.1 |
| Coordinates | 2917727..2918299 (+) | Length | 191 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | POS17_RS13255 | Protein ID | WP_060838972.1 |
| Coordinates | 2917045..2917602 (+) | Length | 186 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| POS17_RS13225 | 2912073..2912354 | - | 282 | WP_060838966.1 | type II toxin-antitoxin system ParD family antitoxin | - |
| POS17_RS13230 | 2912462..2913082 | - | 621 | WP_060838967.1 | LysE family translocator | - |
| POS17_RS13235 | 2913254..2913826 | - | 573 | WP_060838968.1 | inclusion body family protein | - |
| POS17_RS13240 | 2914051..2914680 | - | 630 | WP_060838969.1 | alpha/beta hydrolase | - |
| POS17_RS13245 | 2914913..2916109 | + | 1197 | WP_060838970.1 | PrpF protein | - |
| POS17_RS13250 | 2916514..2916855 | - | 342 | WP_060838971.1 | low molecular weight protein tyrosine phosphatase family protein | - |
| POS17_RS13255 | 2917045..2917602 | + | 558 | WP_060838972.1 | helix-turn-helix domain-containing protein | Antitoxin |
| POS17_RS13260 | 2917727..2918299 | + | 573 | WP_060838973.1 | HD domain-containing protein | Toxin |
| POS17_RS13265 | 2918556..2920736 | + | 2181 | WP_060838974.1 | catalase/peroxidase HPI | - |
| POS17_RS13270 | 2920798..2921484 | - | 687 | WP_060838975.1 | hypothetical protein | - |
| POS17_RS13275 | 2921444..2922064 | - | 621 | WP_060838976.1 | hypothetical protein | - |
| POS17_RS13280 | 2922131..2922559 | - | 429 | WP_060838977.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 191 a.a. Molecular weight: 21555.11 Da Isoelectric Point: 4.7436
>T30784 WP_060838973.1 NZ_AP014627:2917727-2918299 [Pseudomonas sp. Os17]
MTPELLSGRLDFLREAEKLKDVLRSAHTSSGRQESTAEHSWRLCLMALLFEDQLGDLDLLRVLKLCIVHDLGEAIHGDIP
AVAQAAHPDKSQQERDDLQYLARALDAPARQRLLELWDEYEGAASTEARAVKALDKLETLLQHTQGQNPADFDYGFNLDY
GRRYTDASPLFQALRQQIDADTRRRLDAQD
MTPELLSGRLDFLREAEKLKDVLRSAHTSSGRQESTAEHSWRLCLMALLFEDQLGDLDLLRVLKLCIVHDLGEAIHGDIP
AVAQAAHPDKSQQERDDLQYLARALDAPARQRLLELWDEYEGAASTEARAVKALDKLETLLQHTQGQNPADFDYGFNLDY
GRRYTDASPLFQALRQQIDADTRRRLDAQD
Download Length: 573 bp
>T30784 NZ_AP014627:2917727-2918299 [Pseudomonas sp. Os17]
ATGACCCCCGAACTTCTCAGCGGCCGTCTCGACTTTCTCCGTGAAGCGGAAAAACTCAAGGACGTGCTGCGCAGCGCCCA
CACCTCCAGCGGCCGCCAGGAAAGCACCGCCGAGCACAGCTGGCGCCTGTGCCTGATGGCGCTGCTGTTCGAAGACCAAC
TGGGGGACCTGGACCTGCTGCGGGTGCTGAAACTGTGCATCGTCCACGACCTGGGGGAAGCCATCCATGGCGACATCCCG
GCGGTGGCCCAGGCCGCCCACCCGGACAAGAGCCAACAGGAACGCGACGACCTGCAATACCTCGCCCGGGCCCTGGACGC
CCCGGCCCGCCAGCGTCTGCTGGAGCTGTGGGATGAATACGAAGGCGCCGCCAGCACCGAGGCGCGCGCGGTCAAGGCCC
TGGACAAGCTGGAAACCCTGCTGCAACACACCCAGGGCCAGAACCCGGCGGATTTCGACTACGGCTTCAACCTCGATTAC
GGCCGCCGCTACACCGACGCCAGCCCGTTGTTCCAGGCCCTGCGCCAGCAGATCGATGCCGACACCCGGCGCCGCCTCGA
CGCCCAGGACTGA
ATGACCCCCGAACTTCTCAGCGGCCGTCTCGACTTTCTCCGTGAAGCGGAAAAACTCAAGGACGTGCTGCGCAGCGCCCA
CACCTCCAGCGGCCGCCAGGAAAGCACCGCCGAGCACAGCTGGCGCCTGTGCCTGATGGCGCTGCTGTTCGAAGACCAAC
TGGGGGACCTGGACCTGCTGCGGGTGCTGAAACTGTGCATCGTCCACGACCTGGGGGAAGCCATCCATGGCGACATCCCG
GCGGTGGCCCAGGCCGCCCACCCGGACAAGAGCCAACAGGAACGCGACGACCTGCAATACCTCGCCCGGGCCCTGGACGC
CCCGGCCCGCCAGCGTCTGCTGGAGCTGTGGGATGAATACGAAGGCGCCGCCAGCACCGAGGCGCGCGCGGTCAAGGCCC
TGGACAAGCTGGAAACCCTGCTGCAACACACCCAGGGCCAGAACCCGGCGGATTTCGACTACGGCTTCAACCTCGATTAC
GGCCGCCGCTACACCGACGCCAGCCCGTTGTTCCAGGCCCTGCGCCAGCAGATCGATGCCGACACCCGGCGCCGCCTCGA
CGCCCAGGACTGA
Antitoxin
Download Length: 186 a.a. Molecular weight: 20344.30 Da Isoelectric Point: 7.8012
>AT30784 WP_060838972.1 NZ_AP014627:2917045-2917602 [Pseudomonas sp. Os17]
MSAALFTSPHLGLALRRWRLLHRVKQQHAADLFGVAQSSISRWENGRQAMEPAERARLEHLLAANLSAAADQALARLVND
SPRAVHLVCDLTHRLLACSPTRAAQFGVPLSELLGQSLWGFCTEEIVRKEAALDDLGWRAVLAPPSLEFFSGHNDSAIVP
IAPSQCRWTRLNLSDGNAVRLVETL
MSAALFTSPHLGLALRRWRLLHRVKQQHAADLFGVAQSSISRWENGRQAMEPAERARLEHLLAANLSAAADQALARLVND
SPRAVHLVCDLTHRLLACSPTRAAQFGVPLSELLGQSLWGFCTEEIVRKEAALDDLGWRAVLAPPSLEFFSGHNDSAIVP
IAPSQCRWTRLNLSDGNAVRLVETL
Download Length: 558 bp
>AT30784 NZ_AP014627:2917045-2917602 [Pseudomonas sp. Os17]
ATGTCCGCAGCCCTGTTCACCTCACCCCATCTGGGCCTGGCCCTCAGGCGCTGGCGCCTGTTGCACCGGGTCAAGCAGCA
GCACGCCGCCGATCTGTTCGGTGTGGCGCAGTCGAGCATTTCCCGCTGGGAAAACGGCCGGCAAGCCATGGAGCCGGCGG
AGCGTGCGCGCCTGGAGCACCTGCTGGCGGCCAACCTCAGCGCCGCTGCCGATCAGGCCCTGGCGCGGCTGGTGAATGAC
AGCCCGCGCGCCGTGCACCTGGTGTGCGACCTGACCCACCGCCTGCTGGCCTGTTCGCCGACCCGCGCCGCACAGTTCGG
CGTGCCCTTGAGCGAGCTGCTGGGCCAATCGCTGTGGGGCTTTTGCACCGAGGAAATCGTGCGCAAGGAAGCCGCCCTGG
ATGACCTGGGCTGGCGCGCAGTGCTGGCGCCGCCGTCCCTGGAGTTCTTCAGCGGCCACAACGATTCGGCCATCGTGCCC
ATCGCCCCCAGCCAGTGCCGCTGGACCCGCCTCAACCTGTCCGACGGCAACGCCGTGCGGCTGGTGGAAACCCTCTGA
ATGTCCGCAGCCCTGTTCACCTCACCCCATCTGGGCCTGGCCCTCAGGCGCTGGCGCCTGTTGCACCGGGTCAAGCAGCA
GCACGCCGCCGATCTGTTCGGTGTGGCGCAGTCGAGCATTTCCCGCTGGGAAAACGGCCGGCAAGCCATGGAGCCGGCGG
AGCGTGCGCGCCTGGAGCACCTGCTGGCGGCCAACCTCAGCGCCGCTGCCGATCAGGCCCTGGCGCGGCTGGTGAATGAC
AGCCCGCGCGCCGTGCACCTGGTGTGCGACCTGACCCACCGCCTGCTGGCCTGTTCGCCGACCCGCGCCGCACAGTTCGG
CGTGCCCTTGAGCGAGCTGCTGGGCCAATCGCTGTGGGGCTTTTGCACCGAGGAAATCGTGCGCAAGGAAGCCGCCCTGG
ATGACCTGGGCTGGCGCGCAGTGCTGGCGCCGCCGTCCCTGGAGTTCTTCAGCGGCCACAACGATTCGGCCATCGTGCCC
ATCGCCCCCAGCCAGTGCCGCTGGACCCGCCTCAACCTGTCCGACGGCAACGCCGTGCGGCTGGTGGAAACCCTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|