Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 175734..176250 Replicon chromosome
Accession NZ_AP014627
Organism Pseudomonas sp. Os17

Toxin (Protein)


Gene name relE Uniprot ID A0A0D6B9R6
Locus tag POS17_RS00785 Protein ID WP_060836934.1
Coordinates 175969..176250 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0D6BA30
Locus tag POS17_RS00780 Protein ID WP_060841856.1
Coordinates 175734..175979 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
POS17_RS00765 173228..174838 + 1611 WP_060836933.1 glycosyltransferase family 39 protein -
POS17_RS00770 174948..175409 + 462 WP_019093517.1 YbaK/EbsC family protein -
POS17_RS00775 175424..175669 + 246 WP_047300786.1 DUF2789 domain-containing protein -
POS17_RS00780 175734..175979 + 246 WP_060841856.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
POS17_RS00785 175969..176250 + 282 WP_060836934.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
POS17_RS00790 176393..176821 + 429 WP_060836935.1 winged helix DNA-binding protein -
POS17_RS00795 176818..178905 + 2088 WP_060836936.1 FUSC family protein -
POS17_RS00800 178902..179111 + 210 WP_011058538.1 DUF1656 domain-containing protein -
POS17_RS00805 179108..179998 + 891 WP_060836937.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10850.79 Da        Isoelectric Point: 10.5009

>T30780 WP_060836934.1 NZ_AP014627:175969-176250 [Pseudomonas sp. Os17]
MTYRLEFLPSAHKEWNKLGHTLRAQFKKKLAERLEVPRIPADALHGLPDCYKIKLKASGYRLVYQVIEERVVVCVVAVGK
RERGTVYEQARKR

Download         Length: 282 bp

>T30780 NZ_AP014627:175969-176250 [Pseudomonas sp. Os17]
ATGACTTATAGACTTGAGTTCCTGCCTTCGGCACACAAGGAATGGAACAAGTTGGGGCATACCCTTCGAGCACAATTCAA
GAAAAAGCTCGCCGAACGGCTTGAGGTGCCGCGAATCCCGGCTGATGCCCTGCACGGACTTCCCGATTGCTACAAGATCA
AACTCAAGGCTTCGGGTTACCGGCTGGTTTATCAAGTGATCGAAGAACGGGTAGTGGTTTGCGTGGTTGCGGTAGGCAAG
CGCGAGCGTGGAACTGTGTACGAGCAGGCCAGGAAGCGCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8727.04 Da        Isoelectric Point: 4.5164

>AT30780 WP_060841856.1 NZ_AP014627:175734-175979 [Pseudomonas sp. Os17]
MQSILADKAVSVSELKKNPSAVLSGAQGGPVAVLNHNRVMGYMVPAEVFEALMERLDDLELAEIVRARSHETPVPVSLDD
L

Download         Length: 246 bp

>AT30780 NZ_AP014627:175734-175979 [Pseudomonas sp. Os17]
ATGCAGAGCATTCTGGCTGACAAAGCCGTCAGCGTATCCGAGTTGAAGAAAAACCCGTCTGCCGTCTTGAGTGGTGCCCA
GGGGGGACCCGTGGCGGTGTTGAATCACAATCGTGTCATGGGCTACATGGTTCCGGCCGAGGTTTTCGAGGCGTTGATGG
AACGCCTGGATGATCTTGAGCTGGCCGAGATCGTTCGCGCGCGCAGCCATGAGACGCCCGTCCCGGTCAGTCTGGATGAC
TTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D6B9R6

Antitoxin

Source ID Structure
AlphaFold DB A0A0D6BA30

References