Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-YafN |
Location | 175734..176250 | Replicon | chromosome |
Accession | NZ_AP014627 | ||
Organism | Pseudomonas sp. Os17 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A0D6B9R6 |
Locus tag | POS17_RS00785 | Protein ID | WP_060836934.1 |
Coordinates | 175969..176250 (+) | Length | 94 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A0D6BA30 |
Locus tag | POS17_RS00780 | Protein ID | WP_060841856.1 |
Coordinates | 175734..175979 (+) | Length | 82 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
POS17_RS00765 | 173228..174838 | + | 1611 | WP_060836933.1 | glycosyltransferase family 39 protein | - |
POS17_RS00770 | 174948..175409 | + | 462 | WP_019093517.1 | YbaK/EbsC family protein | - |
POS17_RS00775 | 175424..175669 | + | 246 | WP_047300786.1 | DUF2789 domain-containing protein | - |
POS17_RS00780 | 175734..175979 | + | 246 | WP_060841856.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
POS17_RS00785 | 175969..176250 | + | 282 | WP_060836934.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
POS17_RS00790 | 176393..176821 | + | 429 | WP_060836935.1 | winged helix DNA-binding protein | - |
POS17_RS00795 | 176818..178905 | + | 2088 | WP_060836936.1 | FUSC family protein | - |
POS17_RS00800 | 178902..179111 | + | 210 | WP_011058538.1 | DUF1656 domain-containing protein | - |
POS17_RS00805 | 179108..179998 | + | 891 | WP_060836937.1 | HlyD family secretion protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10850.79 Da Isoelectric Point: 10.5009
>T30780 WP_060836934.1 NZ_AP014627:175969-176250 [Pseudomonas sp. Os17]
MTYRLEFLPSAHKEWNKLGHTLRAQFKKKLAERLEVPRIPADALHGLPDCYKIKLKASGYRLVYQVIEERVVVCVVAVGK
RERGTVYEQARKR
MTYRLEFLPSAHKEWNKLGHTLRAQFKKKLAERLEVPRIPADALHGLPDCYKIKLKASGYRLVYQVIEERVVVCVVAVGK
RERGTVYEQARKR
Download Length: 282 bp
>T30780 NZ_AP014627:175969-176250 [Pseudomonas sp. Os17]
ATGACTTATAGACTTGAGTTCCTGCCTTCGGCACACAAGGAATGGAACAAGTTGGGGCATACCCTTCGAGCACAATTCAA
GAAAAAGCTCGCCGAACGGCTTGAGGTGCCGCGAATCCCGGCTGATGCCCTGCACGGACTTCCCGATTGCTACAAGATCA
AACTCAAGGCTTCGGGTTACCGGCTGGTTTATCAAGTGATCGAAGAACGGGTAGTGGTTTGCGTGGTTGCGGTAGGCAAG
CGCGAGCGTGGAACTGTGTACGAGCAGGCCAGGAAGCGCTGA
ATGACTTATAGACTTGAGTTCCTGCCTTCGGCACACAAGGAATGGAACAAGTTGGGGCATACCCTTCGAGCACAATTCAA
GAAAAAGCTCGCCGAACGGCTTGAGGTGCCGCGAATCCCGGCTGATGCCCTGCACGGACTTCCCGATTGCTACAAGATCA
AACTCAAGGCTTCGGGTTACCGGCTGGTTTATCAAGTGATCGAAGAACGGGTAGTGGTTTGCGTGGTTGCGGTAGGCAAG
CGCGAGCGTGGAACTGTGTACGAGCAGGCCAGGAAGCGCTGA
Antitoxin
Download Length: 82 a.a. Molecular weight: 8727.04 Da Isoelectric Point: 4.5164
>AT30780 WP_060841856.1 NZ_AP014627:175734-175979 [Pseudomonas sp. Os17]
MQSILADKAVSVSELKKNPSAVLSGAQGGPVAVLNHNRVMGYMVPAEVFEALMERLDDLELAEIVRARSHETPVPVSLDD
L
MQSILADKAVSVSELKKNPSAVLSGAQGGPVAVLNHNRVMGYMVPAEVFEALMERLDDLELAEIVRARSHETPVPVSLDD
L
Download Length: 246 bp
>AT30780 NZ_AP014627:175734-175979 [Pseudomonas sp. Os17]
ATGCAGAGCATTCTGGCTGACAAAGCCGTCAGCGTATCCGAGTTGAAGAAAAACCCGTCTGCCGTCTTGAGTGGTGCCCA
GGGGGGACCCGTGGCGGTGTTGAATCACAATCGTGTCATGGGCTACATGGTTCCGGCCGAGGTTTTCGAGGCGTTGATGG
AACGCCTGGATGATCTTGAGCTGGCCGAGATCGTTCGCGCGCGCAGCCATGAGACGCCCGTCCCGGTCAGTCTGGATGAC
TTATAG
ATGCAGAGCATTCTGGCTGACAAAGCCGTCAGCGTATCCGAGTTGAAGAAAAACCCGTCTGCCGTCTTGAGTGGTGCCCA
GGGGGGACCCGTGGCGGTGTTGAATCACAATCGTGTCATGGGCTACATGGTTCCGGCCGAGGTTTTCGAGGCGTTGATGG
AACGCCTGGATGATCTTGAGCTGGCCGAGATCGTTCGCGCGCGCAGCCATGAGACGCCCGTCCCGGTCAGTCTGGATGAC
TTATAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0D6B9R6 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0D6BA30 |