Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 5995333..5995922 Replicon chromosome
Accession NZ_AP014623
Organism Pseudomonas chlororaphis subsp. aurantiaca strain StFRB508

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PCAU_RS27160 Protein ID WP_096375557.1
Coordinates 5995623..5995922 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PCAU_RS27155 Protein ID WP_028683469.1
Coordinates 5995333..5995626 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PCAU_RS27135 5990974..5992137 - 1164 WP_096375553.1 acyltransferase -
PCAU_RS27140 5992331..5993521 - 1191 WP_096375554.1 serine hydrolase -
PCAU_RS27145 5993648..5994535 + 888 WP_096375555.1 LysR family transcriptional regulator -
PCAU_RS27150 5994808..5995200 + 393 WP_096375556.1 hypothetical protein -
PCAU_RS27155 5995333..5995626 - 294 WP_028683469.1 putative addiction module antidote protein Antitoxin
PCAU_RS27160 5995623..5995922 - 300 WP_096375557.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PCAU_RS27165 5996093..5996542 + 450 WP_063433162.1 DUF3828 domain-containing protein -
PCAU_RS27170 5996567..5997577 - 1011 WP_172900921.1 NAD(P)-dependent alcohol dehydrogenase -
PCAU_RS27175 5997635..5997934 - 300 WP_009051080.1 ArsR family transcriptional regulator -
PCAU_RS27180 5997998..5999089 - 1092 WP_096375559.1 nitrite reductase, copper-containing -
PCAU_RS27185 5999315..5999557 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
PCAU_RS27190 5999554..6000441 + 888 WP_038575447.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Uncharacterized protein HI1420

(11-92)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11179.95 Da        Isoelectric Point: 9.5786

>T30779 WP_096375557.1 NZ_AP014623:c5995922-5995623 [Pseudomonas chlororaphis subsp. aurantiaca]
MIEIKQVATFMEWENRLKDPTARALIAARIFRLANGLAGDVSPVGEGVSELHIHYGPGYRVYFQPCGLQFVILLCGGDKS
RQGRDIELAKYLARRWSRS

Download         Length: 300 bp

>T30779 NZ_AP014623:c5995922-5995623 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGATCGAGATCAAACAGGTCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATCCCACAGCCAGGGCGTTGATCGC
TGCGCGGATTTTTCGCCTGGCCAACGGCCTTGCCGGTGACGTGTCCCCGGTGGGCGAAGGCGTCAGTGAGTTGCACATCC
ATTACGGGCCGGGCTACCGGGTTTACTTCCAGCCGTGCGGCCTGCAATTCGTCATCCTGTTATGCGGCGGCGACAAGAGT
CGCCAGGGCCGCGATATCGAACTGGCCAAATACCTGGCCCGTCGTTGGAGTCGATCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10444.96 Da        Isoelectric Point: 5.6642

>AT30779 WP_028683469.1 NZ_AP014623:c5995626-5995333 [Pseudomonas chlororaphis subsp. aurantiaca]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLEMTARVHGAS

Download         Length: 294 bp

>AT30779 NZ_AP014623:c5995626-5995333 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGAACGAACCGCTATTCGACTATGACCCCGCCACGGCCTTGCGCGACCCGCAGGCCATTGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCGTTCAGTGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGCGCCCTGGGGCTGGAGATGACGGCGCGGGTGCATGGGGCGTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References