Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2221700..2222285 Replicon chromosome
Accession NZ_AP014623
Organism Pseudomonas chlororaphis subsp. aurantiaca strain StFRB508

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PCAU_RS10410 Protein ID WP_096373678.1
Coordinates 2221992..2222285 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PCAU_RS10405 Protein ID WP_096373677.1
Coordinates 2221700..2221990 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PCAU_RS10390 2217039..2219520 + 2482 Protein_2038 FtsX-like permease family protein -
PCAU_RS10395 2219510..2220586 + 1077 WP_096373675.1 iron ABC transporter permease -
PCAU_RS10400 2220700..2221287 + 588 WP_096373676.1 hypothetical protein -
PCAU_RS10405 2221700..2221990 - 291 WP_096373677.1 putative addiction module antidote protein Antitoxin
PCAU_RS10410 2221992..2222285 - 294 WP_096373678.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PCAU_RS10415 2222520..2223914 - 1395 WP_096373679.1 VOC family protein -
PCAU_RS10420 2224172..2225296 + 1125 WP_096373680.1 diguanylate cyclase -
PCAU_RS10425 2225390..2226634 + 1245 WP_096373681.1 M20/M25/M40 family metallo-hydrolase -
PCAU_RS10430 2226880..2227278 + 399 WP_023968692.1 carboxymuconolactone decarboxylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-97)

Antitoxin

Uncharacterized protein HI1420

(5-90)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10713.30 Da        Isoelectric Point: 10.0959

>T30777 WP_096373678.1 NZ_AP014623:c2222285-2221992 [Pseudomonas chlororaphis subsp. aurantiaca]
MDYEILQTTVFAQWHTTLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNTGAGYRLYFTVRGNTLIVLLLGGDK
STQPADICQARSLAKEF

Download         Length: 294 bp

>T30777 NZ_AP014623:c2222285-2221992 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGGATTACGAGATCCTGCAGACGACCGTCTTTGCCCAATGGCACACCACACTACGGGACCTGCGCGCCAGGATAGCCAT
CGCTCGGCGTATCGAGCGGGCTTCGGCGGGCAACCTGGGCGATGTGAAAAACCTCGGCGGCGGTCTCTCGGAAATGCGCG
TGAACACAGGCGCCGGCTACCGCCTCTATTTCACGGTTCGCGGCAATACCCTCATCGTCCTGCTGCTGGGCGGCGACAAG
TCCACCCAACCTGCCGACATCTGCCAGGCCCGTTCCCTGGCCAAGGAGTTCTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10265.81 Da        Isoelectric Point: 8.0096

>AT30777 WP_096373677.1 NZ_AP014623:c2221990-2221700 [Pseudomonas chlororaphis subsp. aurantiaca]
MSDTLVPFDIAALLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKTTGQGRASLYKAFSPGAKPRFDTVVK
VMRALGLQLCTTVPRG

Download         Length: 291 bp

>AT30777 NZ_AP014623:c2221990-2221700 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGTCCGACACACTGGTTCCCTTCGACATCGCCGCCCTGCTCGACAGCGACCAGGCGATCAGCGAATACCTGTCCCAGGT
CCTGGCCGATGGCGATACCGATGAACTGATCCGCGCCCTGGGCCATGTCGCCAGGGCCCGGGGCATGACGCAGATTGCCA
AGACCACCGGCCAGGGCCGGGCCAGCCTCTACAAGGCCTTTTCCCCGGGCGCCAAGCCGCGCTTCGATACCGTGGTCAAG
GTCATGCGCGCGCTGGGCCTGCAGCTGTGCACCACAGTGCCCCGAGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References