Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 1339040..1339568 Replicon chromosome
Accession NZ_AP014623
Organism Pseudomonas chlororaphis subsp. aurantiaca strain StFRB508

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PCAU_RS06095 Protein ID WP_096373266.1
Coordinates 1339040..1339345 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PCAU_RS06100 Protein ID WP_096373267.1
Coordinates 1339329..1339568 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PCAU_RS06070 1334156..1334698 + 543 WP_007922237.1 XRE family transcriptional regulator -
PCAU_RS06075 1335025..1336044 - 1020 WP_096373263.1 DUF4917 family protein -
PCAU_RS06080 1336202..1337350 + 1149 WP_096373264.1 L-threonine dehydrogenase -
PCAU_RS06085 1337548..1338120 + 573 WP_081362467.1 TetR/AcrR family transcriptional regulator -
PCAU_RS06090 1338340..1339011 + 672 WP_096373265.1 epimerase -
PCAU_RS06095 1339040..1339345 - 306 WP_096373266.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PCAU_RS06100 1339329..1339568 - 240 WP_096373267.1 CopG family ribbon-helix-helix protein Antitoxin
PCAU_RS06105 1339705..1340121 + 417 WP_096373268.1 fosfomycin resistance glutathione transferase -
PCAU_RS06110 1340249..1340887 + 639 WP_016702101.1 LysE family translocator -
PCAU_RS06115 1340999..1342339 + 1341 WP_096373269.1 sensor domain-containing diguanylate cyclase -
PCAU_RS06120 1342478..1343002 + 525 WP_096373270.1 DUF4142 domain-containing protein -
PCAU_RS06125 1343085..1343483 - 399 WP_038581536.1 low affinity iron permease family protein -
PCAU_RS06130 1343668..1344540 - 873 WP_038583918.1 phosphotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11753.43 Da        Isoelectric Point: 10.8916

>T30774 WP_096373266.1 NZ_AP014623:c1339345-1339040 [Pseudomonas chlororaphis subsp. aurantiaca]
MARHVEWLRTALKNLDDEATYIAQDSPQAAAEFVKAILSSIQHLSRFPASGREGRLPGTREWVVPNRPYLIPYRVRQGHL
QILRIFHTRRLPPAGWQDERQ

Download         Length: 306 bp

>T30774 NZ_AP014623:c1339345-1339040 [Pseudomonas chlororaphis subsp. aurantiaca]
CTGGCAAGGCACGTTGAGTGGCTGCGCACCGCCCTCAAGAACCTCGATGACGAAGCCACCTACATTGCACAGGACAGTCC
TCAGGCCGCCGCGGAATTCGTCAAAGCCATCCTGAGCAGCATTCAACACCTGAGCCGTTTTCCTGCCAGTGGTCGCGAAG
GTCGCCTGCCCGGTACCCGGGAGTGGGTGGTCCCCAATCGTCCTTACCTGATCCCCTACCGTGTACGTCAGGGACACCTG
CAGATACTGCGGATTTTCCATACCCGGCGCTTGCCGCCTGCCGGTTGGCAAGACGAACGCCAATAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8692.82 Da        Isoelectric Point: 4.7672

>AT30774 WP_096373267.1 NZ_AP014623:c1339568-1339329 [Pseudomonas chlororaphis subsp. aurantiaca]
MSVMSLRLPDDVANSLAHLAKATGRSKSFLAVDALREYLAREAWQIDEIQKALTEAEAGDFASAEELDNVLTKWTGKAR

Download         Length: 240 bp

>AT30774 NZ_AP014623:c1339568-1339329 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGTCCGTCATGTCCTTGCGCCTGCCCGATGATGTTGCCAATTCCCTGGCTCACTTGGCCAAGGCGACAGGCCGCAGCAA
GTCATTCCTCGCTGTGGATGCACTGAGAGAATATCTGGCCCGCGAAGCCTGGCAAATCGACGAGATCCAGAAAGCCCTGA
CTGAAGCAGAGGCAGGCGACTTCGCCAGCGCCGAAGAGCTGGATAACGTGCTCACTAAATGGACTGGCAAGGCACGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References