Detailed information of TA system TA030772

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 132037..132707
• Replicon: chromosome
• Accession: NZ_AP014623
• Organism: Pseudomonas chlororaphis subsp. aurantiaca strain StFRB508

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: PCAU_RS00575
• Protein ID: WP_081362979.1
• Coordinates: 132037..132465 (-)
• Length: 143 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A0A3G7DZE9
• Locus tag: PCAU_RS00580
• Protein ID: WP_009046453.1
• Coordinates: 132462..132707 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PCAU_RS00560	127156..129414	+	2259	WP_096372785.1	TonB-dependent receptor	-
PCAU_RS00565	129461..130786	+	1326	WP_096372786.1	LLM class flavin-dependent oxidoreductase	-
PCAU_RS00570	130871..131908	+	1038	WP_096372787.1	L-glyceraldehyde 3-phosphate reductase	-
PCAU_RS00575	132037..132465	-	429	WP_081362979.1	type II toxin-antitoxin system VapC family toxin	Toxin
PCAU_RS00580	132462..132707	-	246	WP_009046453.1	plasmid stabilization protein	Antitoxin
PCAU_RS00585	132847..133686	-	840	WP_096372788.1	taurine dioxygenase	-
PCAU_RS00590	133923..134762	-	840	WP_009046455.1	taurine ABC transporter permease TauC	-
PCAU_RS00595	134759..135553	-	795	WP_096372789.1	taurine ABC transporter ATP-binding subunit	-
PCAU_RS00600	135649..136626	-	978	WP_096372790.1	taurine ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-124)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 143 a.a.
• Molecular weight: 15853.36 Da
• Isoelectric Point: 5.4927

>T30772 WP_081362979.1 NZ_AP014623:c132465-132037 [Pseudomonas chlororaphis subsp. aurantiaca]
MIVLDTNVLSELMRPQPDTAVLLWIEAQPVEDLYISAMTMAEILHGIARLPHGKRKQTLHASAVAMFEEDFIDRIVPFGT
QAALYYAHLVSHRERSGQPINLVDAQIAAICRVHDAAIATRNTKDFTDTGLIVINPWLPLEV

Nucleotide

• Length: 429 bp

>T30772 NZ_AP014623:c132465-132037 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGATAGTACTCGACACAAATGTGTTGTCAGAACTGATGCGCCCTCAACCGGATACGGCGGTATTGCTGTGGATCGAAGC
GCAACCCGTCGAGGACCTCTACATCAGCGCTATGACCATGGCCGAGATTCTCCACGGTATCGCGCGCCTGCCCCACGGCA
AGCGCAAACAGACGCTGCATGCATCGGCGGTGGCCATGTTCGAGGAAGACTTCATCGACCGGATCGTACCCTTCGGAACC
CAAGCGGCTCTTTACTACGCGCATCTGGTTTCGCATCGCGAAAGATCAGGCCAGCCGATCAATCTGGTGGATGCGCAAAT
TGCAGCGATATGCCGGGTCCACGACGCCGCGATCGCCACTCGTAACACCAAGGATTTCACCGACACCGGGCTGATCGTTA
TCAACCCCTGGCTGCCGCTCGAGGTCTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9103.27 Da
• Isoelectric Point: 6.2314

>AT30772 WP_009046453.1 NZ_AP014623:c132707-132462 [Pseudomonas chlororaphis subsp. aurantiaca]
MASLTIRNLDDHIKERLRIEAAHNGHSMEEEARLILRRALSRTADSQGLGSRIRARFAETGGVELELPERTEPARLVDLG
E

Nucleotide

• Length: 246 bp

>AT30772 NZ_AP014623:c132707-132462 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGGCCAGCCTTACGATCCGTAATCTGGACGACCACATCAAAGAACGCCTGCGCATCGAGGCCGCTCACAATGGTCATTC
CATGGAAGAAGAAGCCCGATTGATTTTGCGCCGCGCATTGAGCAGGACAGCTGACAGCCAAGGCCTGGGCAGCCGTATCA
GGGCACGCTTTGCCGAGACCGGCGGAGTAGAGCTGGAGCTGCCTGAACGTACCGAACCGGCACGCTTGGTGGACCTGGGC
GAATGA

Structures

Antitoxin

• AlphaFold DB: A0A3G7DZE9