Detailed information of TA system TA030764

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-DinJ
• Location: 1257570..1258107
• Replicon: chromosome
• Accession: NZ_AP014612
• Organism: Streptococcus troglodytae strain TKU 31

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SRT_RS06105
• Protein ID: WP_128833422.1
• Coordinates: 1257570..1257848 (-)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: SRT_RS06110
• Protein ID: WP_128833423.1
• Coordinates: 1257835..1258107 (-)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SRT_RS06090	1253083..1253928	-	846	WP_128833420.1	DegV family protein	-
SRT_RS06095	1253934..1254308	-	375	WP_003088020.1	DUF1149 family protein	-
SRT_RS06100	1254520..1257567	-	3048	WP_128833421.1	type I restriction endonuclease subunit R	-
SRT_RS06105	1257570..1257848	-	279	WP_128833422.1	type II toxin-antitoxin system YafQ family toxin	Toxin
SRT_RS06110	1257835..1258107	-	273	WP_128833423.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
SRT_RS06115	1258181..1259277	-	1097	Protein_1144	anticodon nuclease	-
SRT_RS06120	1259289..1261116	-	1828	Protein_1145	restriction endonuclease subunit S	-
SRT_RS06125	1261109..1262713	-	1605	WP_128833424.1	type I restriction-modification system subunit M	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (3-89)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (8-61)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10638.75 Da
• Isoelectric Point: 10.1364

>T30764 WP_128833422.1 NZ_AP014612:c1257848-1257570 [Streptococcus troglodytae]
MLKIKQTKQFKKSLKKVVKQGKDINKLFAIVELLCQKSELPLALRDHELKGKWKGIRELHIESDWLLAYQVLDNELVLLL
IDTGSHAQMLGM

Nucleotide

• Length: 279 bp

>T30764 NZ_AP014612:c1257848-1257570 [Streptococcus troglodytae]
ATGCTAAAGATTAAGCAAACCAAACAATTTAAGAAATCCTTAAAAAAGGTAGTAAAGCAAGGAAAAGATATTAACAAGCT
TTTTGCTATCGTAGAATTATTATGTCAAAAATCAGAACTTCCCTTAGCATTGAGAGATCATGAGTTAAAAGGAAAATGGA
AAGGCATTAGAGAACTTCATATTGAATCAGACTGGCTGTTGGCTTATCAAGTTTTAGATAACGAACTTGTCTTACTCTTG
ATTGATACAGGAAGTCATGCACAGATGTTAGGAATGTAA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 10081.43 Da
• Isoelectric Point: 4.4482

>AT30764 WP_128833423.1 NZ_AP014612:c1258107-1257835 [Streptococcus troglodytae]
MVVKNKANINIKIDLEDKATADAIFAHMGLTTSAAVNMFIKRVIDDQALPFTPRVKNTLDIALEQAKNDDVETFDSFDDW
KSEMSAYAKD

Nucleotide

• Length: 273 bp

>AT30764 NZ_AP014612:c1258107-1257835 [Streptococcus troglodytae]
ATGGTTGTAAAAAATAAGGCGAATATCAATATCAAAATTGATTTAGAGGATAAAGCAACAGCAGATGCTATTTTTGCCCA
CATGGGTCTAACAACAAGTGCTGCTGTCAATATGTTTATTAAACGTGTCATTGATGATCAAGCTCTGCCATTTACTCCAA
GAGTAAAAAATACTTTGGACATTGCTTTAGAGCAGGCTAAAAATGATGATGTTGAAACTTTTGATAGTTTTGATGATTGG
AAATCAGAGATGAGTGCCTATGCTAAAGATTAA