30696

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) SmuAT/-
Location 164721..165682 Replicon chromosome
Accession NZ_AP014571
Organism Streptococcus mutans LP13

Toxin (Protein)


Gene name smuT Uniprot ID -
Locus tag SMUNUM_RS00800 Protein ID WP_002265708.1
Coordinates 164721..165236 (+) Length 172 a.a.

Antitoxin (Protein)


Gene name smuA Uniprot ID -
Locus tag SMUNUM_RS00805 Protein ID WP_002277323.1
Coordinates 165236..165682 (+) Length 149 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SMUNUM_RS00775 (SMNUM_0131) 160168..160875 + 708 WP_002282856.1 MerR family transcriptional regulator -
SMUNUM_RS00780 (SMNUM_0132) 160911..161903 - 993 WP_002267808.1 BtrH N-terminal domain-containing protein -
SMUNUM_RS00785 (SMNUM_0133) 162092..162646 - 555 WP_002264861.1 PadR family transcriptional regulator -
SMUNUM_RS00790 (SMNUM_0134) 162959..163705 + 747 WP_002264862.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
SMUNUM_RS00795 (SMNUM_0135) 163729..164589 + 861 WP_019322456.1 DegV family protein -
SMUNUM_RS00800 (SMNUM_0136) 164721..165236 + 516 WP_002265708.1 hypothetical protein Toxin
SMUNUM_RS00805 (SMNUM_0137) 165236..165682 + 447 WP_002277323.1 hypothetical protein Antitoxin
SMUNUM_RS00810 (SMNUM_0138) 165679..165873 + 195 WP_002273989.1 helix-turn-helix transcriptional regulator -
SMUNUM_RS00815 (SMNUM_0139) 166266..166712 + 447 WP_002262993.1 50S ribosomal protein L13 -
SMUNUM_RS00820 (SMNUM_0140) 166737..167129 + 393 WP_002297278.1 30S ribosomal protein S9 -
SMUNUM_RS00825 (SMNUM_0141) 167239..167889 - 651 Protein_141 tyrosine-type recombinase/integrase -
SMUNUM_RS00830 168055..168838 + 784 Protein_142 ABC-2 family transporter protein -
SMUNUM_RS00835 (SMNUM_0144) 169349..169753 + 405 WP_286216849.1 hypothetical protein -
SMUNUM_RS00840 169772..170326 + 555 WP_286216850.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(10-63)


Sequences

Toxin        


Download         Length: 172 a.a.        Molecular weight: 19562.22 Da        Isoelectric Point: 9.8654

>T30696 WP_002265708.1 NZ_AP014571:164721-165236 [Streptococcus mutans LP13]
MFDLVVNLILLVIVIGGFVFLRFYADKKGKREYDERQLLMQKKAYTNAAWVVMGFNLVLVIWGEVLAKYISLSFAGTANL
FLIVGVFVCHSILNDAYFTARKNKKFLYVYAVIIAIQIFTVYQNWSQGSFGHDGHIYLTGEKAMSLLFILTFAVIFLVTA
YKTIQDKREGK

Download         Length: 516 bp

>T30696 NZ_AP014571:164721-165236 [Streptococcus mutans LP13]
ATGTTTGACCTTGTTGTTAATTTGATTTTATTGGTTATTGTGATAGGTGGATTTGTCTTCTTAAGATTCTATGCGGATAA
GAAAGGCAAGCGAGAATACGATGAACGCCAGTTACTTATGCAAAAGAAAGCTTATACCAATGCGGCTTGGGTTGTTATGG
GTTTCAATCTTGTTCTTGTGATATGGGGTGAAGTGTTAGCAAAATATATCTCGCTATCCTTTGCAGGTACTGCCAATCTC
TTTCTTATCGTAGGCGTCTTTGTCTGCCACAGTATCTTAAACGATGCTTATTTCACAGCAAGAAAAAACAAAAAATTCCT
CTATGTGTATGCCGTTATTATTGCTATTCAAATTTTCACTGTTTATCAAAATTGGAGTCAAGGCAGCTTTGGTCATGACG
GACATATTTATCTAACAGGAGAAAAAGCAATGAGTTTATTGTTTATCTTGACTTTTGCTGTCATTTTTCTAGTAACTGCT
TATAAAACGATTCAGGATAAGAGAGAGGGAAAGTGA

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 17010.31 Da        Isoelectric Point: 9.5767

>AT30696 WP_002277323.1 NZ_AP014571:165236-165682 [Streptococcus mutans LP13]
MKMEKSNKQVIYDERQQQIQLKSYSLSFWFVMFILYFATFGKTDLLLNIAFWGGLVLNFCYSTLRGVGPFVDPRFGKIAK
IGRLAAVPLIFLGMLVFLVAIIMSILEHDSLRESIIKCSYLGLSGFWLICMGASIVYRHYLDKKEADK

Download         Length: 447 bp

>AT30696 NZ_AP014571:165236-165682 [Streptococcus mutans LP13]
ATGAAAATGGAAAAGTCAAATAAACAAGTCATTTACGATGAACGTCAGCAGCAAATTCAACTTAAAAGTTATAGTCTTTC
ATTTTGGTTTGTTATGTTTATACTCTATTTTGCAACTTTTGGAAAGACTGATTTGTTGCTTAATATCGCTTTTTGGGGAG
GACTTGTTCTTAATTTTTGCTACAGTACTCTAAGAGGTGTTGGTCCTTTTGTTGATCCACGTTTTGGAAAAATTGCAAAA
ATCGGTCGTTTGGCCGCTGTTCCCCTTATTTTTTTGGGAATGCTAGTCTTTCTTGTTGCTATCATAATGTCTATTCTAGA
ACATGATAGTTTAAGAGAATCTATCATAAAATGCTCCTACTTAGGCTTATCTGGTTTTTGGCTAATTTGTATGGGAGCAA
GTATCGTCTACCGTCATTATCTTGATAAGAAAGAAGCAGACAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References