Detailed information of TA system TA030676

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1791867..1792434
• Replicon: chromosome
• Accession: NZ_AP014568
• Organism: Serpentinomonas raichei strain A1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SRAA_RS08375
• Protein ID: WP_197538527.1
• Coordinates: 1791867..1792145 (-)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A060NPR6
• Locus tag: SRAA_RS08380
• Protein ID: WP_029462395.1
• Coordinates: 1792183..1792434 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SRAA_RS08345	1787843..1788424	-	582	WP_052467529.1	chemotaxis protein CheW	-
SRAA_RS08350	1788446..1788808	-	363	WP_045532061.1	response regulator	-
SRAA_RS08355	1788825..1789226	-	402	WP_045532063.1	response regulator	-
SRAA_RS08360	1789286..1789459	-	174	WP_029462391.1	rubredoxin	-
SRAA_RS08365	1789551..1790501	+	951	WP_045532065.1	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	-
SRAA_RS08370	1790520..1791827	+	1308	WP_045532067.1	glutamate-1-semialdehyde 2,1-aminomutase	-
SRAA_RS08375	1791867..1792145	-	279	WP_197538527.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SRAA_RS08380	1792183..1792434	-	252	WP_029462395.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
SRAA_RS08385	1792501..1793880	-	1380	WP_045532071.1	tRNA 5-hydroxyuridine modification protein YegQ	-
SRAA_RS08390	1793945..1794331	-	387	WP_029462397.1	DUF779 domain-containing protein	-
SRAA_RS08395	1794331..1795851	-	1521	WP_045532073.1	aldehyde dehydrogenase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-76)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (8-78)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10404.30 Da
• Isoelectric Point: 10.0309

>T30676 WP_197538527.1 NZ_AP014568:c1792145-1791867 [Serpentinomonas raichei]
MPAALEEWNALDGSVKTVLKKLLAKRLEQPHVPGAELHRDLRNCYKIKLLKQGYRLVYRVEDEVLVLLVLAVAKRADGSA
YRAAIERLIAQP

Nucleotide

• Length: 279 bp

>T30676 NZ_AP014568:c1792145-1791867 [Serpentinomonas raichei]
CTGCCGGCCGCTCTGGAAGAATGGAATGCGCTGGACGGCAGTGTCAAAACCGTCCTCAAAAAACTGCTGGCCAAGCGCCT
GGAGCAGCCCCATGTGCCGGGTGCCGAGCTGCATCGCGATTTGCGCAACTGCTACAAGATCAAACTCCTCAAGCAGGGCT
ACCGACTGGTCTATCGGGTTGAGGATGAGGTCTTGGTCTTGCTCGTGCTGGCCGTGGCCAAGCGCGCAGATGGGTCCGCT
TACCGCGCGGCCATCGAGCGCTTGATTGCGCAGCCATAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9412.81 Da
• Isoelectric Point: 4.7906

>AT30676 WP_029462395.1 NZ_AP014568:c1792434-1792183 [Serpentinomonas raichei]
MDSIYADHSISMSEFKRNPAQVLRTAGEKPVAVLNHNRPAFYMITPKLFEALVEELGERELVSLARQRLTLIDSAVEVDL
EQL

Nucleotide

• Length: 252 bp

>AT30676 NZ_AP014568:c1792434-1792183 [Serpentinomonas raichei]
ATGGATTCGATCTACGCCGACCATTCCATCAGCATGTCGGAGTTCAAACGCAACCCGGCACAGGTGCTGCGCACGGCTGG
TGAGAAGCCCGTGGCCGTGCTCAACCACAACCGCCCGGCTTTCTACATGATCACCCCCAAGCTCTTTGAGGCACTGGTCG
AAGAGCTGGGCGAGCGTGAGTTGGTGAGTCTGGCCCGCCAGCGCCTGACGCTGATCGACAGCGCGGTCGAGGTCGATCTT
GAGCAGCTCTGA

Structures

Antitoxin

• AlphaFold DB: A0A060NPR6