Detailed information of TA system TA030675

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 1711615..1712384
• Replicon: chromosome
• Accession: NZ_AP014568
• Organism: Serpentinomonas raichei strain A1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: SRAA_RS07970
• Protein ID: WP_082039980.1
• Coordinates: 1711615..1712130 (-)
• Length: 172 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A0A060NJ30
• Locus tag: SRAA_RS07975
• Protein ID: WP_045531957.1
• Coordinates: 1712127..1712384 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SRAA_RS07950	1707450..1707677	+	228	WP_045531951.1	addiction module protein	-
SRAA_RS12305	1707674..1707967	+	294	WP_082039979.1	type II toxin-antitoxin system RelE/ParE family toxin	-
SRAA_RS07955	1707988..1709682	-	1695	WP_045533550.1	NAD+ synthase	-
SRAA_RS07960	1709761..1710303	-	543	WP_045531953.1	inorganic diphosphatase	-
SRAA_RS07965	1710461..1711618	+	1158	WP_045531955.1	GTP 3',8-cyclase MoaA	-
SRAA_RS07970	1711615..1712130	-	516	WP_082039980.1	type II toxin-antitoxin system VapC family toxin	Toxin
SRAA_RS07975	1712127..1712384	-	258	WP_045531957.1	plasmid stability protein stbC	Antitoxin
SRAA_RS07980	1712563..1713714	+	1152	WP_045531959.1	iron-containing alcohol dehydrogenase	-
SRAA_RS07985	1713724..1714794	-	1071	WP_045533554.1	phospholipase	-
SRAA_RS07990	1714803..1715615	-	813	WP_045531961.1	HDOD domain-containing protein	-
SRAA_RS07995	1715623..1716450	-	828	WP_045531962.1	HDOD domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-124)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 172 a.a.
• Molecular weight: 17705.27 Da
• Isoelectric Point: 5.6844

>T30675 WP_082039980.1 NZ_AP014568:c1712130-1711615 [Serpentinomonas raichei]
MILIDTNVISELWKPAPDAQVQAWLDAQAIETLYLSAVTVAELRFGLMSMPAGKRRAVYLDRLQQEVLAAFAGRVLAFDL
HAALAYADLMARARAAGKAIGMTDGYIAGTAAAHGFMVATRDTSPFEAAGLSVVNPWQAAQNPSPTDAPQPGVPRGSGGP
VGGSVGGSVAV

Nucleotide

• Length: 516 bp

>T30675 NZ_AP014568:c1712130-1711615 [Serpentinomonas raichei]
ATGATCCTCATCGACACCAACGTGATTTCCGAATTGTGGAAGCCCGCACCCGATGCGCAGGTGCAGGCTTGGCTCGACGC
CCAAGCCATCGAAACCCTCTACCTGAGCGCCGTTACCGTGGCCGAACTGCGTTTTGGCCTGATGTCGATGCCGGCCGGCA
AACGGCGCGCGGTCTATCTGGATCGCTTGCAGCAAGAGGTGCTGGCGGCCTTTGCCGGGCGTGTGCTGGCTTTTGACTTG
CACGCCGCGCTGGCCTATGCCGACTTGATGGCGCGGGCGCGAGCCGCAGGCAAGGCCATAGGTATGACCGATGGATACAT
TGCTGGCACGGCCGCCGCTCACGGCTTCATGGTGGCCACACGCGACACCAGCCCGTTTGAGGCCGCCGGCCTGAGCGTCG
TCAACCCGTGGCAGGCGGCGCAGAACCCCAGCCCGACCGATGCACCGCAGCCCGGCGTGCCGCGCGGTAGTGGCGGGCCT
GTGGGTGGCTCTGTGGGAGGCTCTGTGGCGGTTTAG

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9309.65 Da
• Isoelectric Point: 11.0635

>AT30675 WP_045531957.1 NZ_AP014568:c1712384-1712127 [Serpentinomonas raichei]
MAVVTIRNLPNEVHRALRVRAAQHGRSTEAEIRAILEAVARPTERIKLGSLLASIAREAGPLSAAEAQHFSQLRDQTPAQ
PMSFE

Nucleotide

• Length: 258 bp

>AT30675 NZ_AP014568:c1712384-1712127 [Serpentinomonas raichei]
ATGGCCGTCGTCACCATTCGCAACCTGCCCAACGAGGTGCACCGTGCGCTGCGCGTACGCGCGGCCCAGCATGGCCGCAG
CACCGAGGCCGAAATTCGCGCGATTCTGGAGGCGGTTGCCCGACCGACAGAGCGCATCAAACTGGGTTCTTTGTTGGCCT
CCATCGCCCGCGAGGCGGGGCCCTTGAGCGCGGCCGAGGCGCAGCATTTCAGCCAACTGCGCGACCAGACCCCGGCCCAA
CCCATGAGCTTCGAATGA

Structures

Antitoxin

• AlphaFold DB: A0A060NJ30