Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1577796..1579261 Replicon chromosome
Accession NZ_AP014568
Organism Serpentinomonas raichei strain A1

Toxin (Protein)


Gene name rlegT Uniprot ID A0A060NHF5
Locus tag SRAA_RS07270 Protein ID WP_045531780.1
Coordinates 1577796..1578659 (-) Length 288 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A060NIU7
Locus tag SRAA_RS07275 Protein ID WP_045531782.1
Coordinates 1578656..1579261 (-) Length 202 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SRAA_RS07245 1573873..1574382 + 510 WP_045531771.1 hypothetical protein -
SRAA_RS07250 1574469..1575803 + 1335 WP_052467517.1 hypothetical protein -
SRAA_RS07255 1576293..1576667 + 375 WP_144318725.1 hypothetical protein -
SRAA_RS07260 1576694..1577041 - 348 WP_045531778.1 DNA-binding transcriptional regulator -
SRAA_RS12285 1577004..1577370 - 367 Protein_1444 type II toxin-antitoxin system RelE/ParE family toxin -
SRAA_RS07265 1577457..1577657 - 201 WP_045531779.1 hypothetical protein -
SRAA_RS07270 1577796..1578659 - 864 WP_045531780.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
SRAA_RS07275 1578656..1579261 - 606 WP_045531782.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
SRAA_RS07280 1579490..1579891 - 402 Protein_1448 helix-turn-helix domain-containing protein -
SRAA_RS07285 1579962..1580333 - 372 WP_045531784.1 transcriptional regulator -
SRAA_RS07290 1580352..1580654 - 303 WP_045531786.1 type II toxin-antitoxin system HigB family toxin -
SRAA_RS07295 1581417..1581686 + 270 WP_045531788.1 CopG family transcriptional regulator -
SRAA_RS07300 1581673..1582041 + 369 WP_045531790.1 type II toxin-antitoxin system RelE/ParE family toxin -
SRAA_RS07305 1582149..1582484 + 336 WP_045533503.1 XRE family transcriptional regulator -
SRAA_RS07310 1582942..1583487 - 546 WP_144318726.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-265)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(13-55)


Sequences

Toxin        


Download         Length: 288 a.a.        Molecular weight: 31379.18 Da        Isoelectric Point: 7.3568

>T30674 WP_045531780.1 NZ_AP014568:c1578659-1577796 [Serpentinomonas raichei]
MNPANPNVAASVRARLLNVAKTQGVDFNQVLVRFALERILYRLTQSQHADRFLLKGALLFTLWYDMPHRATRDADLLGFG
ASDLASVAETFRDIAAVAVDDGIAFDPASVTVDEIRKEAGYGGVRVFIAGELAKARCKTQIDVGFGDAVTPAPVDSVYPV
LLDDLPAPRLRAYPTYTVIAEKLHAIALLGMSNSRLKDYFDLSVLLERETLDTDLLAQAIKATFERRGMSVPNAVPLGLT
DEFAHNSSRQALWLAFLKKNELPPKPLPAIVDRLRSALAPALNRAAL

Download         Length: 864 bp

>T30674 NZ_AP014568:c1578659-1577796 [Serpentinomonas raichei]
ATGAACCCCGCCAATCCCAACGTCGCTGCGTCCGTCCGTGCGCGCCTGCTCAACGTTGCCAAAACGCAGGGTGTCGATTT
CAATCAGGTGCTGGTGCGCTTTGCGCTGGAACGCATCCTCTACCGCCTGACCCAATCGCAGCACGCCGATCGTTTTCTGC
TCAAGGGCGCGCTGCTGTTCACGCTCTGGTACGACATGCCGCACCGGGCCACGCGCGATGCCGATCTGCTCGGCTTCGGC
GCGAGCGATTTGGCATCGGTTGCCGAAACTTTCCGTGACATCGCCGCCGTGGCTGTTGACGACGGCATTGCATTCGATCC
GGCCTCGGTCACGGTGGATGAGATCCGCAAGGAAGCCGGCTACGGCGGCGTGCGCGTGTTCATCGCAGGCGAACTGGCCA
AGGCGCGCTGCAAGACGCAGATCGACGTTGGCTTCGGCGATGCCGTCACACCCGCACCGGTGGATTCGGTCTATCCGGTC
CTGCTGGATGATCTGCCCGCACCCCGGCTGCGAGCCTACCCGACGTACACGGTCATCGCGGAAAAACTCCACGCCATCGC
CCTGCTGGGCATGAGCAACAGCCGCCTGAAGGACTACTTCGATCTGTCGGTGCTGCTGGAGCGAGAAACCCTGGACACCG
ATTTGCTGGCCCAAGCGATCAAAGCCACCTTCGAGCGGCGCGGCATGTCCGTGCCCAATGCGGTGCCGCTTGGGCTGACG
GACGAGTTCGCGCACAATTCCTCGCGGCAGGCGCTGTGGCTGGCGTTTCTCAAGAAGAACGAGCTTCCCCCCAAGCCCCT
GCCTGCCATCGTGGATCGGTTGCGATCTGCCTTGGCCCCTGCGTTGAACCGAGCCGCTCTTTGA

Antitoxin


Download         Length: 202 a.a.        Molecular weight: 22272.87 Da        Isoelectric Point: 9.9048

>AT30674 WP_045531782.1 NZ_AP014568:c1579261-1578656 [Serpentinomonas raichei]
MLPDTHTQRVLGLASQKGLLRASDLDAIDAPRVVLTRLTAAGLLEKIGRGLYRLPGSQWSEHESLVTVATKVPQAVFCLL
TALQFHELTTQLPRQVWIAMPRGSHAPRFDYPPIKMVQFTGAAYTAGIDEVERDGVTLRVYGVAKTLADCFKHRNKIGLD
VALEALKDVRARNKASVDDIWRNAKVCRVANVMRPYLESIG

Download         Length: 606 bp

>AT30674 NZ_AP014568:c1579261-1578656 [Serpentinomonas raichei]
ATGCTCCCTGACACCCATACCCAGCGCGTCCTCGGCCTGGCCAGCCAGAAGGGGCTGCTGCGTGCCAGCGATCTGGACGC
CATCGATGCGCCCCGGGTCGTCCTGACGCGTCTGACGGCCGCTGGTTTGCTGGAGAAAATTGGGCGTGGTCTGTACCGCC
TGCCGGGCTCTCAGTGGTCTGAACACGAAAGTCTGGTGACCGTCGCCACCAAGGTGCCGCAAGCCGTGTTCTGCCTGCTC
ACGGCGCTGCAGTTCCACGAGCTCACAACCCAATTGCCGCGCCAGGTCTGGATCGCCATGCCGCGCGGCAGCCATGCCCC
ACGGTTCGACTACCCGCCGATCAAGATGGTGCAGTTCACGGGTGCAGCCTACACGGCGGGCATCGATGAAGTTGAACGCG
ATGGCGTCACGCTGCGGGTGTACGGCGTGGCCAAGACCCTGGCGGACTGCTTCAAGCACCGCAACAAGATCGGCCTGGAC
GTGGCGCTGGAGGCACTGAAGGACGTCCGGGCCCGCAACAAGGCATCGGTCGATGACATCTGGCGCAACGCCAAGGTCTG
CCGCGTGGCCAACGTGATGCGGCCCTATCTGGAGAGCATCGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A060NHF5

Antitoxin

Source ID Structure
AlphaFold DB A0A060NIU7

References