Detailed information of TA system TA030670

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 999017..999663
• Replicon: chromosome
• Accession: NZ_AP014568
• Organism: Serpentinomonas raichei strain A1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: A0A060NMR2
• Locus tag: SRAA_RS04740
• Protein ID: WP_045531237.1
• Coordinates: 999253..999663 (+)
• Length: 137 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: SRAA_RS04735
• Protein ID: WP_082040082.1
• Coordinates: 999017..999253 (+)
• Length: 79 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-123)

Antitoxin

• SpoVT-AbrB domain (7-56)

Sequences

Toxin

Protein

• Length: 137 a.a.
• Molecular weight: 14896.09 Da
• Isoelectric Point: 6.8716

>T30670 WP_045531237.1 NZ_AP014568:999253-999663 [Serpentinomonas raichei]
MLRYLLDTNIVIYVLKRRPVEVLSTFNANASRIAISSITLAELLHGAEKSSRVSENLSAIEDFCSRLAVLPYGAKAAQHY
GAIRDALEKLGQPIGVNDLHIAGHARSEGMVLVSNNVSEFARVPALEVENWVRAPE

Nucleotide

• Length: 411 bp

>T30670 NZ_AP014568:999253-999663 [Serpentinomonas raichei]
ATGCTGCGCTACCTGCTTGACACCAACATCGTCATCTACGTGTTGAAACGACGCCCGGTCGAGGTTCTGTCGACCTTCAA
CGCCAATGCCAGTCGAATAGCCATTTCTTCCATTACCCTGGCCGAACTCTTGCACGGCGCCGAAAAAAGCAGCCGCGTGA
GCGAGAACTTGTCTGCCATCGAGGACTTCTGCAGCCGCTTGGCCGTGTTGCCCTATGGCGCCAAGGCCGCACAGCACTAT
GGTGCCATTCGAGACGCCCTGGAAAAACTCGGTCAACCCATCGGGGTGAATGACCTGCACATTGCCGGCCACGCGCGCAG
TGAGGGGATGGTTTTGGTGAGCAATAACGTTTCGGAATTTGCGCGCGTTCCTGCGCTCGAGGTAGAGAATTGGGTCCGCG
CCCCAGAGTAA

Antitoxin

Protein

• Length: 79 a.a.
• Molecular weight: 8779.00 Da
• Isoelectric Point: 7.2040

>AT30670 WP_082040082.1 NZ_AP014568:999017-999253 [Serpentinomonas raichei]
MSIGTVFVNNRTQAVRLPLDVRLPEGVHKVEIRAKGNERIIAPLGQTWDSFFLGGPPQVSEDFLPQRATQHQSEREVL

Nucleotide

• Length: 237 bp

>AT30670 NZ_AP014568:999017-999253 [Serpentinomonas raichei]
ATGTCTATCGGCACTGTGTTTGTCAATAACCGCACCCAAGCCGTGCGCCTCCCATTGGACGTTCGCCTGCCCGAGGGTGT
ACACAAAGTAGAGATACGGGCCAAGGGTAACGAGCGCATCATCGCGCCCCTAGGTCAAACGTGGGACAGCTTCTTCCTGG
GTGGCCCGCCCCAAGTCAGTGAAGACTTCTTGCCTCAACGTGCCACGCAGCACCAGTCGGAGCGGGAAGTGCTCTGA

Structures

Toxin

• AlphaFold DB: A0A060NMR2