Detailed information of TA system TA030656

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-YefM
• Location: 219219..219750
• Replicon: chromosome
• Accession: NZ_AP014568
• Organism: Serpentinomonas raichei strain A1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SRAA_RS01005
• Protein ID: WP_045530439.1
• Coordinates: 219484..219750 (+)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: A0A060NFA8
• Locus tag: SRAA_RS01000
• Protein ID: WP_045530435.1
• Coordinates: 219219..219473 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SRAA_RS00980	216576..216953	-	378	WP_045530431.1	50S ribosomal protein L7/L12	-
SRAA_RS00985	216976..217497	-	522	WP_045533010.1	50S ribosomal protein L10	-
SRAA_RS00990	217793..218488	-	696	WP_045530433.1	50S ribosomal protein L1	-
SRAA_RS00995	218490..218921	-	432	WP_029461860.1	50S ribosomal protein L11	-
SRAA_RS01000	219219..219473	+	255	WP_045530435.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
SRAA_RS01005	219484..219750	+	267	WP_045530439.1	Txe/YoeB family addiction module toxin	Toxin
SRAA_RS01010	219915..220748	+	834	WP_045530441.1	hypothetical protein	-
SRAA_RS12375	220762..221031	+	270	WP_144318674.1	hypothetical protein	-
SRAA_RS12380	221018..221512	+	495	WP_144318675.1	hypothetical protein	-
SRAA_RS11975	221496..222035	+	540	WP_052467431.1	hypothetical protein	-
SRAA_RS01025	222234..223601	+	1368	WP_045530335.1	IS1380 family transposase	-
SRAA_RS01030	223980..224486	+	507	WP_144318676.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	89753..294621	204868

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (7-86)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10643.11 Da
• Isoelectric Point: 9.7188

>T30656 WP_045530439.1 NZ_AP014568:219484-219750 [Serpentinomonas raichei]
MQPSLRFSSSAWAHYTYWMVQDKATLRRINTLIADAMRNPYEGIGKPEPLKHEFSGWWSRRIDQEHRMVYRLREQTLEIA
ALRYHYGE

Nucleotide

• Length: 267 bp

>T30656 NZ_AP014568:219484-219750 [Serpentinomonas raichei]
ATGCAGCCAAGCCTACGCTTTTCGTCCAGCGCTTGGGCGCATTACACATACTGGATGGTGCAGGACAAGGCCACCCTGCG
CCGCATTAACACCCTGATCGCCGATGCCATGCGCAACCCCTACGAGGGCATCGGCAAACCCGAGCCGCTCAAACACGAGT
TCAGCGGTTGGTGGTCGCGCCGCATCGATCAGGAGCACCGCATGGTTTATCGCTTGCGTGAGCAGACGCTGGAAATTGCG
GCGCTGCGTTACCACTACGGCGAGTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9357.53 Da
• Isoelectric Point: 4.6471

>AT30656 WP_045530435.1 NZ_AP014568:219219-219473 [Serpentinomonas raichei]
MQVLSYSEARANFAHLLDKVNNDHAPILITRQGGKPAVLVSLDDFNAWQETAYLMNSPANRRMLRQSMDELDVGGGTDQT
LLEP

Nucleotide

• Length: 255 bp

>AT30656 NZ_AP014568:219219-219473 [Serpentinomonas raichei]
ATGCAAGTTCTGAGCTACAGCGAAGCGCGGGCCAATTTTGCGCACCTGCTTGACAAGGTCAACAACGACCATGCGCCCAT
TCTCATCACCCGCCAAGGGGGCAAGCCCGCCGTGTTGGTCAGCCTAGACGACTTCAACGCATGGCAGGAAACGGCCTACC
TGATGAACTCGCCCGCCAACCGCCGCATGCTGCGCCAGTCCATGGACGAACTGGACGTGGGTGGTGGCACCGATCAAACC
TTGCTGGAGCCTTGA

Structures

Antitoxin

• AlphaFold DB: A0A060NFA8