Detailed information of TA system TA030654

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-YefM
• Location: 502256..502764
• Replicon: chromosome
• Accession: NZ_AP014546
• Organism: Neptunomonas japonica JAMM 1380

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: NEJAP_RS02250
• Protein ID: WP_201349105.1
• Coordinates: 502256..502516 (-)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: NEJAP_RS02255
• Protein ID: WP_201349106.1
• Coordinates: 502513..502764 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NEJAP_RS02235	497909..499183	-	1275	WP_201349102.1	ABC transporter permease	-
NEJAP_RS02240	499308..500363	-	1056	WP_201349103.1	ABC transporter substrate-binding protein	-
NEJAP_RS02245	500424..501545	-	1122	WP_201349104.1	ABC transporter ATP-binding protein	-
NEJAP_RS02250	502256..502516	-	261	WP_201349105.1	Txe/YoeB family addiction module toxin	Toxin
NEJAP_RS02255	502513..502764	-	252	WP_201349106.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
NEJAP_RS02260	503302..503769	+	468	WP_201349107.1	hypothetical protein	-
NEJAP_RS02265	504108..504839	+	732	WP_201349108.1	hypothetical protein	-
NEJAP_RS02270	504843..505103	-	261	WP_201349109.1	hypothetical protein	-
NEJAP_RS02275	505784..506014	+	231	WP_201349110.1	hypothetical protein	-
NEJAP_RS02280	506276..506608	+	333	WP_201349111.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	441808..663328	221520

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (1-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 10387.90 Da
• Isoelectric Point: 10.1743

>T30654 WP_201349105.1 NZ_AP014546:c502516-502256 [Neptunomonas japonica JAMM 1380]
MKLTFSTQAWEQYLYWQTTNKKILKRINWLIKDIQKSPNEGIGKPEPLKHGLSGYWSRRVNDEHRIVYKHQDDTILIAQL
RYHYGT

Nucleotide

• Length: 261 bp

>T30654 NZ_AP014546:c502516-502256 [Neptunomonas japonica JAMM 1380]
ATGAAGTTAACGTTCTCGACTCAAGCCTGGGAACAATATCTCTATTGGCAAACTACCAATAAGAAAATACTAAAACGTAT
CAATTGGCTAATTAAAGATATTCAAAAAAGCCCAAATGAAGGCATAGGAAAGCCTGAGCCTTTAAAGCATGGCTTATCAG
GGTACTGGTCGCGACGTGTCAATGATGAGCATCGAATTGTGTACAAACATCAGGATGATACGATTCTGATCGCTCAACTA
CGCTACCACTATGGCACATAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9212.46 Da
• Isoelectric Point: 4.3915

>AT30654 WP_201349106.1 NZ_AP014546:c502764-502513 [Neptunomonas japonica JAMM 1380]
MNVISYTAARANLASTMANVCNDHAPIIITRKNEAPVIMISLEDYNAMEETTYLLRSPTNARNLLESIAELETGKGTERE
LLE

Nucleotide

• Length: 252 bp

>AT30654 NZ_AP014546:c502764-502513 [Neptunomonas japonica JAMM 1380]
ATGAATGTAATAAGCTACACAGCAGCTAGAGCAAATTTAGCGAGCACTATGGCAAATGTCTGTAATGATCATGCGCCTAT
AATTATCACTCGCAAAAATGAAGCGCCCGTCATAATGATATCTTTAGAAGACTATAACGCAATGGAAGAGACTACATATT
TACTCAGGTCTCCAACCAACGCTAGAAACCTATTAGAGTCTATAGCCGAACTGGAAACAGGCAAGGGAACAGAAAGAGAA
CTTCTTGAATGA