Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Xre(antitoxin) |
| Location | 3378856..3379976 | Replicon | chromosome |
| Accession | NZ_AP014545 | ||
| Organism | Amphritea japonica ATCC BAA-1530 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | A0A7R6P581 |
| Locus tag | AMJAP_RS15545 | Protein ID | WP_019623034.1 |
| Coordinates | 3378856..3379605 (-) | Length | 250 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A7R6P5F1 |
| Locus tag | AMJAP_RS15550 | Protein ID | WP_019623035.1 |
| Coordinates | 3379605..3379976 (-) | Length | 124 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AMJAP_RS15525 | 3375032..3375910 | - | 879 | WP_019623031.1 | LysR family transcriptional regulator | - |
| AMJAP_RS15530 | 3376054..3376827 | + | 774 | WP_019623032.1 | ferredoxin--NADP reductase | - |
| AMJAP_RS15540 | 3377559..3378779 | + | 1221 | WP_019623033.1 | GGDEF domain-containing protein | - |
| AMJAP_RS15545 | 3378856..3379605 | - | 750 | WP_019623034.1 | RES family NAD+ phosphorylase | Toxin |
| AMJAP_RS15550 | 3379605..3379976 | - | 372 | WP_019623035.1 | MbcA/ParS/Xre antitoxin family protein | Antitoxin |
| AMJAP_RS15555 | 3380085..3381818 | - | 1734 | WP_019623036.1 | YdiU family protein | - |
| AMJAP_RS15560 | 3382099..3382641 | - | 543 | WP_201356468.1 | DoxX family protein | - |
| AMJAP_RS15565 | 3382657..3383526 | - | 870 | WP_019623038.1 | DNA-binding domain-containing protein | - |
| AMJAP_RS15570 | 3383526..3384470 | - | 945 | WP_019623039.1 | DUF692 domain-containing protein | - |
| AMJAP_RS15575 | 3384445..3384738 | - | 294 | WP_201356469.1 | DUF2282 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 250 a.a. Molecular weight: 27750.15 Da Isoelectric Point: 4.5560
>T30653 WP_019623034.1 NZ_AP014545:c3379605-3378856 [Amphritea japonica ATCC BAA-1530]
MIWQACDGVEQIKPIAGTLYRLVESQEQVATTGYVDTLEEQAILEKLLEASKPDYPEEITAGLHYLLSTPFRYPPLEWGS
RFGSKYEPSLFYGGELLESTLAESAYYRFVFLLAMEGEPPGKRLNTEHTLFTVTYSTQRGILLQHSPFNTYADQLTHPQD
YASSQALGTEMRKAGVEAFQYLSARSTESGVCAALYTATAFTHNQPDTTAQWLCELTTTGVTFKAVASPRTYHYPLSQFA
VDGELPLPA
MIWQACDGVEQIKPIAGTLYRLVESQEQVATTGYVDTLEEQAILEKLLEASKPDYPEEITAGLHYLLSTPFRYPPLEWGS
RFGSKYEPSLFYGGELLESTLAESAYYRFVFLLAMEGEPPGKRLNTEHTLFTVTYSTQRGILLQHSPFNTYADQLTHPQD
YASSQALGTEMRKAGVEAFQYLSARSTESGVCAALYTATAFTHNQPDTTAQWLCELTTTGVTFKAVASPRTYHYPLSQFA
VDGELPLPA
Download Length: 750 bp
>T30653 NZ_AP014545:c3379605-3378856 [Amphritea japonica ATCC BAA-1530]
ATGATCTGGCAGGCCTGTGACGGTGTAGAGCAGATCAAACCCATAGCGGGTACTTTATACCGACTGGTTGAGAGTCAGGA
GCAAGTGGCGACGACAGGTTATGTTGATACACTCGAAGAACAGGCGATACTGGAAAAGTTGCTGGAAGCCTCAAAACCCG
ACTATCCGGAAGAAATTACAGCAGGGCTTCATTATCTGCTGAGCACGCCTTTTCGCTACCCGCCACTGGAATGGGGGTCG
CGCTTTGGGAGCAAATACGAGCCCAGTCTGTTCTACGGAGGGGAATTACTGGAAAGTACACTGGCAGAGTCTGCTTATTA
TCGGTTTGTCTTCTTGCTGGCAATGGAGGGTGAACCACCCGGTAAACGGCTCAACACAGAGCACACCTTGTTTACGGTTA
CCTACAGTACACAACGGGGCATACTGCTTCAGCACTCCCCATTTAATACCTATGCAGATCAGCTAACTCATCCGCAGGAT
TATGCTTCGTCACAAGCGCTTGGAACAGAAATGCGTAAAGCGGGTGTGGAAGCGTTCCAGTATCTTTCTGCCCGGTCAAC
TGAATCGGGGGTATGCGCAGCACTCTATACGGCAACCGCGTTTACACATAATCAGCCTGATACAACCGCACAGTGGCTCT
GTGAACTGACAACAACCGGAGTGACCTTCAAAGCCGTTGCTTCCCCCCGAACCTATCATTACCCGCTGTCACAATTCGCA
GTGGATGGAGAGCTGCCGCTGCCGGCCTGA
ATGATCTGGCAGGCCTGTGACGGTGTAGAGCAGATCAAACCCATAGCGGGTACTTTATACCGACTGGTTGAGAGTCAGGA
GCAAGTGGCGACGACAGGTTATGTTGATACACTCGAAGAACAGGCGATACTGGAAAAGTTGCTGGAAGCCTCAAAACCCG
ACTATCCGGAAGAAATTACAGCAGGGCTTCATTATCTGCTGAGCACGCCTTTTCGCTACCCGCCACTGGAATGGGGGTCG
CGCTTTGGGAGCAAATACGAGCCCAGTCTGTTCTACGGAGGGGAATTACTGGAAAGTACACTGGCAGAGTCTGCTTATTA
TCGGTTTGTCTTCTTGCTGGCAATGGAGGGTGAACCACCCGGTAAACGGCTCAACACAGAGCACACCTTGTTTACGGTTA
CCTACAGTACACAACGGGGCATACTGCTTCAGCACTCCCCATTTAATACCTATGCAGATCAGCTAACTCATCCGCAGGAT
TATGCTTCGTCACAAGCGCTTGGAACAGAAATGCGTAAAGCGGGTGTGGAAGCGTTCCAGTATCTTTCTGCCCGGTCAAC
TGAATCGGGGGTATGCGCAGCACTCTATACGGCAACCGCGTTTACACATAATCAGCCTGATACAACCGCACAGTGGCTCT
GTGAACTGACAACAACCGGAGTGACCTTCAAAGCCGTTGCTTCCCCCCGAACCTATCATTACCCGCTGTCACAATTCGCA
GTGGATGGAGAGCTGCCGCTGCCGGCCTGA
Antitoxin
Download Length: 124 a.a. Molecular weight: 13413.67 Da Isoelectric Point: 11.3344
>AT30653 WP_019623035.1 NZ_AP014545:c3379976-3379605 [Amphritea japonica ATCC BAA-1530]
MSAQLKQRPDAAAVLCKAMFNASEQLTLNQQELGRVVGINRTGVSRLKQSGLLDPASKRGELALLLIRAARALFALSGGN
HDWIKHFMRSNNKLTGGIPAEQMQSVQGLMRVVTYLDAIRGKV
MSAQLKQRPDAAAVLCKAMFNASEQLTLNQQELGRVVGINRTGVSRLKQSGLLDPASKRGELALLLIRAARALFALSGGN
HDWIKHFMRSNNKLTGGIPAEQMQSVQGLMRVVTYLDAIRGKV
Download Length: 372 bp
>AT30653 NZ_AP014545:c3379976-3379605 [Amphritea japonica ATCC BAA-1530]
ATGTCTGCACAACTGAAGCAACGACCTGATGCGGCTGCCGTGCTTTGTAAGGCGATGTTCAACGCGTCTGAGCAACTGAC
ACTGAACCAGCAAGAGCTAGGCAGAGTCGTTGGTATTAATCGCACCGGGGTATCACGTCTTAAACAGAGCGGTTTACTGG
ATCCTGCATCCAAGCGGGGTGAACTGGCATTGCTATTGATTCGCGCTGCACGGGCTCTCTTTGCATTGTCCGGTGGTAAT
CATGACTGGATCAAGCACTTTATGCGTTCAAACAATAAACTGACTGGCGGCATTCCTGCGGAACAGATGCAGAGTGTTCA
GGGTTTGATGCGTGTTGTCACTTATCTGGATGCTATCCGGGGCAAGGTGTAA
ATGTCTGCACAACTGAAGCAACGACCTGATGCGGCTGCCGTGCTTTGTAAGGCGATGTTCAACGCGTCTGAGCAACTGAC
ACTGAACCAGCAAGAGCTAGGCAGAGTCGTTGGTATTAATCGCACCGGGGTATCACGTCTTAAACAGAGCGGTTTACTGG
ATCCTGCATCCAAGCGGGGTGAACTGGCATTGCTATTGATTCGCGCTGCACGGGCTCTCTTTGCATTGTCCGGTGGTAAT
CATGACTGGATCAAGCACTTTATGCGTTCAAACAATAAACTGACTGGCGGCATTCCTGCGGAACAGATGCAGAGTGTTCA
GGGTTTGATGCGTGTTGTCACTTATCTGGATGCTATCCGGGGCAAGGTGTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A7R6P581 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A7R6P5F1 |